Discovery of the inhibitory effect of a phosphatidylinositol derivative on P-glycoprotein by virtual screening followed by in vitro cellular studies (Q28486121)

From Wikidata

Jump to navigation Jump to search

scientific article

Language	Label	Description	Also known as
English	Discovery of the inhibitory effect of a phosphatidylinositol derivative on P-glycoprotein by virtual screening followed by in vitro cellular studies	scientific article

Statements

scholarly article

0 references

Discovery of the inhibitory effect of a phosphatidylinositol derivative on P-glycoprotein by virtual screening followed by in vitro cellular studies (English)

0 references

virtual screening

1 reference

based on heuristic

inferred from title

object named as

Xavier Lucas

1

0 references

author name string

Silke Simon

2

0 references

Rolf Schubert

3

0 references

Stefan Günther

4

0 references

language of work or name

0 references

publication date

2013

0 references

0 references

8

0 references

4

0 references

e60679

0 references

copyright license

Creative Commons Attribution 4.0 International

9 April 2013

1 reference

April 2022 Public Data File from Crossref

copyright status

0 references

ChEMBL: a large-scale bioactivity database for drug discovery

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3621910

19 March 2017

Structure of P-glycoprotein reveals a molecular basis for poly-specific drug binding

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3621910

19 March 2017

Membrane lipids: where they are and how they behave

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3621910

19 March 2017

Multiple molecular mechanisms for multidrug resistance transporters

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3621910

19 March 2017

The SWISS-MODEL workspace: a web-based environment for protein structure homology modelling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3621910

19 March 2017

ZINC--a free database of commercially available compounds for virtual screening

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3621910

19 March 2017

Galaxy: a platform for interactive large-scale genome analysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3621910

7 April 2017

Inositol polyphosphate multikinase signaling in the regulation of metabolism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3621910

29 September 2017

Targeting MDR in breast and lung cancer: discriminating its potential importance from the failure of drug resistance reversal studies.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3621910

29 September 2017

P-glycoprotein-ATPase modulation: the molecular mechanisms

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3621910

29 September 2017

How actin gets the PIP.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3621910

29 September 2017

Molecular pathways: regulation and therapeutic implications of multidrug resistance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3621910

29 September 2017

Three decades of P-gp inhibitors: skimming through several generations and scaffolds.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3621910

29 September 2017

Phosphoinositide function in cytokinesis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3621910

29 September 2017

The role of the ATP-binding cassette transporter P-glycoprotein in the transport of β-amyloid across the blood-brain barrier

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3621910

29 September 2017

Exhaustive sampling of docking poses reveals binding hypotheses for propafenone type inhibitors of P-glycoprotein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3621910

29 September 2017

P-glycoprotein related drug interactions: clinical importance and a consideration of disease states

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3621910

29 September 2017

New insights into the mechanisms of gastric cancer multidrug resistance and future perspectives

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3621910

29 September 2017

Search for genetic markers and functional variants involved in the development of opiate and cocaine addiction and treatment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3621910

29 September 2017

Multidrug efflux pumps: substrate selection in ATP-binding cassette multidrug efflux pumps--first come, first served?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3621910

29 September 2017

In vitro P-glycoprotein assays to predict the in vivo interactions of P-glycoprotein with drugs in the central nervous system

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3621910

29 September 2017

Allosteric modulation bypasses the requirement for ATP hydrolysis in regenerating low affinity transition state conformation of human P-glycoprotein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3621910

29 September 2017

Plasma membrane phosphoinositide organization by protein electrostatics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3621910

29 September 2017

Interaction of LDS-751 and rhodamine 123 with P-glycoprotein: evidence for simultaneous binding of both drugs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3621910

29 September 2017

Effect of pluronic P85 on ATPase activity of drug efflux transporters

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3621910

29 September 2017

Mammalian drug efflux transporters of the ATP binding cassette (ABC) family: an overview.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3621910

29 September 2017

Effects of steroids and verapamil on P-glycoprotein ATPase activity: progesterone, desoxycorticosterone, corticosterone and verapamil are mutually non-exclusive modulators

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3621910

29 September 2017

The human intestinal epithelial cell line Caco-2; pharmacological and pharmacokinetic applications

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3621910

29 September 2017

Characterization of the human colon carcinoma cell line (Caco-2) as a model system for intestinal epithelial permeability

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3621910

29 September 2017

Human intestinal P-glycoprotein activity estimated by the model substrate digoxin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3621910

2 June 2018

Human jejunal permeability of cyclosporin A: influence of surfactants on P-glycoprotein efflux in Caco-2 cells

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0060679

21 January 2018

Effects of nonionic surfactants on membrane transporters in Caco-2 cell monolayers

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0060679

21 January 2018

Shedding light on drug transport: structure and function of the P-glycoprotein multidrug transporter (ABCB1).

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0060679

21 January 2018

The membrane lipid environment modulates drug interactions with the P-glycoprotein multidrug transporter.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0060679

21 January 2018

Vitamin E TPGS P-glycoprotein inhibition mechanism: influence on conformational flexibility, intracellular ATP levels, and role of time and site of access

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0060679

21 January 2018

Phosphatidylinositol inhibits vascular endothelial growth factor-A--induced migration of human umbilical vein endothelial cells

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0060679

21 January 2018

Effects of Alzheimer's disease-related beta amyloid protein fragments on enzymes metabolizing phosphoinositides in brain.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0060679

21 January 2018

Soybean-derived phosphatidylinositol inhibits in vivo low concentrations of amyloid beta protein-induced degeneration of hippocampal neurons in V337M human tau-expressing mice.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0060679

21 January 2018

Phosphatidylinositol increases HDL-C levels in humans

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0060679

21 January 2018

Inhibitory effect of phospholipids on P-glycoprotein: cellular studies in Caco-2, MDCKII mdr1 and MDCKII wildtype cells and P-gp ATPase activity measurements

1 reference

https://pubmed.ncbi.nlm.nih.gov/23593281

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Anti-obesity effect of phosphatidylinositol on diet-induced obesity in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/23593281

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1371/JOURNAL.PONE.0060679

0 references

2013PLoSO...860679L

0 references

0 references

0 references

ResearchGate publication ID

0 references

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q28486121&oldid=1972554842"