Multiple molecular mechanisms for multidrug resistance transporters (Q28297705)

https://api.crossref.org/works/10.1038%2FNATURE05630

7 January 2021

Phylogeny of multidrug transporters

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05630

7 January 2021

ABC Transporters: From Microorganisms to Man

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https://api.crossref.org/works/10.1038%2FNATURE05630

7 January 2021

A surface glycoprotein modulating drug permeability in Chinese hamster ovary cell mutants

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05630

7 January 2021

Multidrug resistance in cancer: role of ATP-dependent transporters

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05630

7 January 2021

A bacterial antibiotic-resistance gene that complements the human multidrug-resistance P-glycoprotein gene

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05630

7 January 2021

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05630

7 January 2021

Structure of the multidrug resistance P-glycoprotein to 2.5 nm resolution determined by electron microscopy and image analysis.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05630

7 January 2021

Repacking of the transmembrane domains of P-glycoprotein during the transport ATPase cycle

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05630

7 January 2021

Three-dimensional structures of the mammalian multidrug resistance P-glycoprotein demonstrate major conformational changes in the transmembrane domains upon nucleotide binding

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05630

7 January 2021

Three-dimensional structure of P-glycoprotein: the transmembrane regions adopt an asymmetric configuration in the nucleotide-bound state.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05630

7 January 2021

Structure of a bacterial multidrug ABC transporter

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05630

7 January 2021

The packing of the transmembrane segments of human multidrug resistance P-glycoprotein is revealed by disulfide cross-linking analysis.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05630

7 January 2021

An atomic detail model for the human ATP binding cassette transporter P‐glycoprotein derived from disulphide cross‐ linking and homology modeling

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05630

7 January 2021

ATP binding to the motor domain from an ABC transporter drives formation of a nucleotide sandwich dimer

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05630

7 January 2021

The E. coli BtuCD structure: a framework for ABC transporter architecture and mechanism

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05630

7 January 2021

An inward-facing conformation of a putative metal-chelate-type ABC transporter

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05630

7 January 2021

The ATP switch model for ABC transporters

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05630

7 January 2021

Structural basis of energy transduction in the transport cycle of MsbA.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05630

7 January 2021

Evidence for two nonidentical drug-interaction sites in the human P-glycoprotein

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05630

7 January 2021

Drug binding sites on P-glycoprotein are altered by ATP binding prior to nucleotide hydrolysis

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05630

7 January 2021

The vinblastine binding site adopts high- and low-affinity conformations during a transport cycle of P-glycoprotein

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05630

7 January 2021

Role of carboxylate residues adjacent to the conserved core Walker B motifs in the catalytic cycle of multidrug resistance protein 1 (ABCC1).

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05630

7 January 2021

The homodimeric ATP-binding cassette transporter LmrA mediates multidrug transport by an alternating two-site (two-cylinder engine) mechanism

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05630

7 January 2021

CFTR channel opening by ATP-driven tight dimerization of its nucleotide-binding domains

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05630

7 January 2021

Is the multidrug transporter a flippase?

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05630

7 January 2021

Multidrug resistance in Lactococcus lactis: evidence for ATP-dependent drug extrusion from the inner leaflet of the cytoplasmic membrane.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05630

7 January 2021

Recent progress in understanding the mechanism of P-glycoprotein-mediated drug efflux.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05630

7 January 2021

Communication between multiple drug binding sites on P-glycoprotein

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05630

7 January 2021

Positively cooperative sites for drug transport by P-glycoprotein with distinct drug specificities

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05630

7 January 2021

Evidence for two interacting ligand binding sites in human multidrug resistance protein 2 (ATP binding cassette C2).

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05630

7 January 2021

Interaction of LDS-751 and rhodamine 123 with P-glycoprotein: evidence for simultaneous binding of both drugs

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05630

7 January 2021

Dynamic movements of organelles containing Niemann-Pick C1 protein: NPC1 involvement in late endocytic events

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05630

7 January 2021

Hedgehog-mediated patterning of the mammalian embryo requires transporter-like function of dispatched

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05630

7 January 2021

Bypassing the periplasm: reconstitution of the AcrAB multidrug efflux pump of Escherichia coli

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05630

7 January 2021

Crystal structure of bacterial multidrug efflux transporter AcrB

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05630

7 January 2021

Crystal structures of a multidrug transporter reveal a functionally rotating mechanism.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05630

7 January 2021

Structural Basis of Multiple Drug-Binding Capacity of the AcrB Multidrug Efflux Pump

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05630

7 January 2021

Structural asymmetry of AcrB trimer suggests a peristaltic pump mechanism.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05630

7 January 2021

Crystal structure of the bacterial membrane protein TolC central to multidrug efflux and protein export

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05630

7 January 2021

Aminoglycosides are captured from both periplasm and cytoplasm by the AcrD multidrug efflux transporter of Escherichia coli

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05630

7 January 2021

Three-dimensional structure of the bacterial multidrug transporter EmrE shows it is an asymmetric homodimer

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05630

7 January 2021

Exploring the binding domain of EmrE, the smallest multidrug transporter

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05630

7 January 2021

On parallel and antiparallel topology of a homodimeric multidrug transporter.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05630

7 January 2021

Identification and evolution of dual-topology membrane proteins

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05630

7 January 2021

A model for coupling of H(+) and substrate fluxes based on "time-sharing" of a common binding site

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05630

7 January 2021

Structure and mechanism of the lactose permease of Escherichia coli

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05630

7 January 2021

Structure and mechanism of the glycerol-3-phosphate transporter from Escherichia coli

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05630

7 January 2021

Structure of the multidrug transporter EmrD from Escherichia coli

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05630

7 January 2021

Promiscuity in the geometry of electrostatic interactions between the Escherichia coli multidrug resistance transporter MdfA and cationic substrates

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05630

7 January 2021

Energetics of wild-type and mutant multidrug resistance secondary transporter LmrP of Lactococcus lactis.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05630

7 January 2021

The secondary multidrug transporter LmrP contains multiple drug interaction sites.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05630

7 January 2021

Alkalitolerance: a biological function for a multidrug transporter in pH homeostasis.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05630

7 January 2021

Lactose permease as a paradigm for membrane transport proteins (Review).

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05630

7 January 2021

Structural basis of multidrug recognition by BmrR, a transcription activator of a multidrug transporter

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05630

7 January 2021

Mechanism of ligand recognition by BmrR, the multidrug-responding transcriptional regulator: mutational analysis of the ligand-binding site

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05630

7 January 2021

Structural mechanisms of QacR induction and multidrug recognition

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05630

7 January 2021

Structural mechanism of the simultaneous binding of two drugs to a multidrug-binding protein

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05630

7 January 2021

Mystery of multidrug transporters: the answer can be simple

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05630

7 January 2021

The structural basis of sequence-independent peptide binding by OppA protein

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05630

7 January 2021

The human nuclear xenobiotic receptor PXR: structural determinants of directed promiscuity

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05630

7 January 2021

The insect attractant 1-octen-3-ol is the natural ligand of bovine odorant-binding protein

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05630

7 January 2021

RETRACTED: Structure of MsbA from E. coli: a homolog of the multidrug resistance ATP binding cassette (ABC) transporters

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05630

7 January 2021

Structure of the multidrug resistance efflux transporter EmrE from Escherichia coli

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05630

7 January 2021

A General Theory of Membrane Transport From Studies of Bacteria

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05630

7 January 2021

Homozygous disruption of the murine mdr2 P-glycoprotein gene leads to a complete absence of phospholipid from bile and to liver disease

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05630

7 January 2021

cDNA cloning of the hepatocyte canalicular isoform of the multidrug resistance protein, cMrp, reveals a novel conjugate export pump deficient in hyperbilirubinemic mutant rats

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05630

7 January 2021

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05630

7 January 2021

Evidence for simultaneous binding of dissimilar substrates by the Escherichia coli multidrug transporter MdfA.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05630

7 January 2021

Cotransport of reduced glutathione with bile salts by MRP4 (ABCC4) localized to the basolateral hepatocyte membrane

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05630

7 January 2021

Identifiers

DOI

10.1038/NATURE05630

1 reference

Consolidated OpenCitations Corpus – April 2017

Dimensions Publication ID

1387619

1020303794

0 references

Fatcat ID

release_fo4lpjbip5gs5dqllnj45kvrbe

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/fo4lpjbip5gs5dqllnj45kvrbe

24 November 2022

mapped directly with Wikidata item

1387619

1 reference

Consolidated OpenCitations Corpus – April 2017

Consolidated OpenCitations Corpus – April 2017

1 reference