A small natural molecule promotes mitochondrial fusion through inhibition of the deubiquitinase USP30 (Q28504988)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24513856%20AND%20SRC:MED&resulttype=core&format=json

7 March 2020

title

A small natural molecule promotes mitochondrial fusion through inhibition of the deubiquitinase USP30 (English)

2 references

24 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24513856%20AND%20SRC:MED&resulttype=core&format=json

7 March 2020

1 reference

GOA release 2020-03-11

Mitofusin 2

1 reference

Ubiquitin specific peptidase 30

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

1 reference

6

1 reference

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7 March 2020

Xiaohu Huang

12

1 reference

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7 March 2020

0 references

Wen Yue

1

2 references

24 January 2017

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7 March 2020

Ziheng Chen

2

2 references

24 January 2017

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7 March 2020

Haiyang Liu

3

2 references

24 January 2017

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7 March 2020

Chen Yan

4

2 references

24 January 2017

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7 March 2020

Ming Chen

5

2 references

24 January 2017

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7 March 2020

Chaojun Yan

7

2 references

24 January 2017

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7 March 2020

Hao Wu

8

2 references

24 January 2017

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7 March 2020

Lei Du

9

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24 January 2017

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7 March 2020

Yueying Wang

10

2 references

24 January 2017

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7 March 2020

Jinhua Liu

11

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7 March 2020

Laixin Xia

13

2 references

24 January 2017

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7 March 2020

Lei Liu

14

2 references

24 January 2017

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7 March 2020

Xiaohui Wang

15

2 references

24 January 2017

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7 March 2020

Haijing Jin

16

2 references

24 January 2017

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7 March 2020

Jun Wang

17

2 references

24 January 2017

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7 March 2020

Zhiyin Song

18

2 references

24 January 2017

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7 March 2020

Xiaojiang Hao

19

2 references

24 January 2017

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7 March 2020

Quan Chen

20

2 references

24 January 2017

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7 March 2020

publication date

11 February 2014

1 reference

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7 March 2020

2 references

24 January 2017

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7 March 2020

volume

24

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7 March 2020

page(s)

482-496

1 reference

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7 March 2020

issue

4

2 references

24 January 2017

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MiD49 and MiD51, new components of the mitochondrial fission machinery

7 March 2020

cites work

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Mff is an essential factor for mitochondrial recruitment of Drp1 during mitochondrial fission in mammalian cells

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19 March 2017

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Dnm1 forms spirals that are structurally tailored to fit mitochondria

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OPA1 requires mitofusin 1 to promote mitochondrial fusion

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19 March 2017

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Mitofusins Mfn1 and Mfn2 coordinately regulate mitochondrial fusion and are essential for embryonic development

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19 March 2017

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7 April 2017

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Mutations in the mitochondrial GTPase mitofusin 2 cause Charcot-Marie-Tooth neuropathy type 2A

7 April 2017

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7 April 2017

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7 April 2017

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7 April 2017

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Natural diterpenoid compound elevates expression of Bim protein, which interacts with antiapoptotic protein Bcl-2, converting it to proapoptotic Bax-like molecule.

22 April 2017

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29 September 2017

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A diterpenoid derivative 15-oxospiramilactone inhibits Wnt/β-catenin signaling and colon cancer cell tumorigenesis

29 September 2017

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Parkin ubiquitinates Drp1 for proteasome-dependent degradation: implication of dysregulated mitochondrial dynamics in Parkinson disease

29 September 2017

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The soluble form of Bax regulates mitochondrial fusion via MFN2 homotypic complexes

29 September 2017

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Bcr-Abl ubiquitination and Usp9x inhibition block kinase signaling and promote CML cell apoptosis

29 September 2017

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Deubiquitinase inhibition by small-molecule WP1130 triggers aggresome formation and tumor cell apoptosis.

29 September 2017

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Mitochondrial remodeling following fission inhibition by 15d-PGJ2 involves molecular changes in mitochondrial fusion protein OPA1.

29 September 2017

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Mitochondrial fusion is required for mtDNA stability in skeletal muscle and tolerance of mtDNA mutations

29 September 2017

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Inhibition of mitochondrial division through covalent modification of Drp1 protein by 15 deoxy-Delta(12,14)-prostaglandin J2.

29 September 2017

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Emerging roles of deubiquitinases in cancer-associated pathways

29 September 2017

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Novel mitochondrial extensions provide evidence for a link between microtubule-directed movement and mitochondrial fission

29 September 2017

1 reference

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Chemical inhibition of the mitochondrial division dynamin reveals its role in Bax/Bak-dependent mitochondrial outer membrane permeabilization

29 September 2017

1 reference

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Functions and dysfunctions of mitochondrial dynamics

29 September 2017

1 reference

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Complementation between mouse Mfn1 and Mfn2 protects mitochondrial fusion defects caused by CMT2A disease mutations

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3975501

Mitofusin 1 and 2 play distinct roles in mitochondrial fusion reactions via GTPase activity

29 September 2017

1 reference

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Structural basis of mitochondrial tethering by mitofusin complexes.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3975501

Regulation of mitochondrial morphology by USP30, a deubiquitinating enzyme present in the mitochondrial outer membrane

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3975501

Changes in mitochondrial shape and distribution induced by ethacrynic acid and the transient formation of a mitochondrial reticulum

2 June 2018

1 reference

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Mitochondrial fusion protects against neurodegeneration in the cerebellum.

2 June 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2014.20

Two Deubiquitylases Act on Mitofusin and Regulate Mitochondrial Fusion along Independent Pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2014.20

Molecular mechanisms of coupled monoubiquitination

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCR.2014.20

21 January 2018

Identifiers

DOI

10.1038/CR.2014.20

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24513856%20AND%20SRC:MED&resulttype=core&format=json

7 March 2020

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24513856%20AND%20SRC:MED&resulttype=core&format=json

7 March 2020

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24513856%20AND%20SRC:MED&resulttype=core&format=json