CCT chaperonin complex is required for efficient delivery of anthrax toxin into the cytosol of host cells (Q28505441)

Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3683768/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

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Membrane insertion of anthrax protective antigen and cytoplasmic delivery of lethal factor occur at different stages of the endocytic pathway

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Identification of the cellular receptor for anthrax toxin

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Prefoldin, a chaperone that delivers unfolded proteins to cytosolic chaperonin

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Proteolytic inactivation of MAP-kinase-kinase by anthrax lethal factor

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GRP78(BiP) facilitates the cytosolic delivery of anthrax lethal factor (LF) in vivo and functions as an unfoldase in vitro.

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Chaperonin TRiC/CCT participates in replication of hepatitis C virus genome via interaction with the viral NS5B protein

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Role of CypA and Hsp90 in membrane translocation mediated by anthrax protective antigen

29 September 2017

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Association of the influenza virus RNA polymerase subunit PB2 with the host chaperonin CCT.

29 September 2017

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Membrane translocation by anthrax toxin

29 September 2017

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The interaction network of the chaperonin CCT

29 September 2017

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COPI coatomer complex proteins facilitate the translocation of anthrax lethal factor across vesicular membranes in vitro

29 September 2017

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Anthrax lethal toxin and Salmonella elicit the common cell death pathway of caspase-1-dependent pyroptosis via distinct mechanisms

29 September 2017

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29 September 2017

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Identification of the TRiC/CCT substrate binding sites uncovers the function of subunit diversity in eukaryotic chaperonins

29 September 2017

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Substantial CCT activity is required for cell cycle progression and cytoskeletal organization in mammalian cells.

29 September 2017

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Evidence that translocation of anthrax toxin's lethal factor is initiated by entry of its N terminus into the protective antigen channel

29 September 2017

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The host cell chaperone Hsp90 is essential for translocation of the binary Clostridium botulinum C2 toxin into the cytosol

29 September 2017

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The cytosolic entry of diphtheria toxin catalytic domain requires a host cell cytosolic translocation factor complex

29 September 2017

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Eukaryotic chaperonin CCT stabilizes actin and tubulin folding intermediates in open quasi-native conformations

29 September 2017

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Characterization of membrane translocation by anthrax protective antigen

29 September 2017

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The t-complex polypeptide 1 complex is a chaperonin for tubulin and actin in vivo.

29 September 2017

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The structure of CCT-Hsc70 NBD suggests a mechanism for Hsp70 delivery of substrates to the chaperonin.

29 September 2017

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DNA fragmentation and cytolysis in U937 cells treated with diphtheria toxin or other inhibitors of protein synthesis

2 June 2018

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Anthrax oedema toxin induces anthrax toxin receptor expression in monocyte-derived cells

2 June 2018

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A phenylalanine clamp catalyzes protein translocation through the anthrax toxin pore

21 January 2018

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Cyclophilin A facilitates translocation of the Clostridium botulinum C2 toxin across membranes of acidified endosomes into the cytosol of mammalian cells

21 January 2018

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Mutational screen identifies critical amino acid residues of beta-actin mediating interaction between its folding intermediates and eukaryotic cytosolic chaperonin CCT.

21 January 2018

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Protein Translocation through the Anthrax Toxin Transmembrane Pore is Driven by a Proton Gradient

21 January 2018

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Effect of redox environment on the in vitro and in vivo folding of RTEM-1 beta-lactamase and Escherichia coli alkaline phosphatase.

21 January 2018

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Folding of nascent polypeptide chains in a high molecular mass assembly with molecular chaperones

27 November 2018

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