Evidence that DeltaNp73 promotes neuronal survival by p53-dependent and p53-independent mechanisms (Q28505661)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15483136%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

title

Evidence that DeltaNp73 promotes neuronal survival by p53-dependent and p53-independent mechanisms (English)

2 references

24 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15483136%20AND%20SRC:MED&resulttype=core&format=json

Mitogen-activated protein kinase 8

4 January 2020

main subject

1 reference

Transformation related protein 53

GOA release 2020-03-11

1 reference

Transformation related protein 73

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

author

Anna Lee

1

1 reference

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4 January 2020

6

Freda D Miller

1 reference

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4 January 2020

author name string

Patrizia Zanassi

3

2 references

24 January 2017

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4 January 2020

Daniel K Ho

2

1 reference

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4 January 2020

Gregory S Walsh

4

1 reference

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4 January 2020

David R Kaplan

5

1 reference

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4 January 2020

language of work or name

English

0 references

publication date

1 October 2004

1 reference

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4 January 2020

published in

Journal of Neuroscience

2 references

24 January 2017

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4 January 2020

volume

24

2 references

24 January 2017

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4 January 2020

issue

41

2 references

24 January 2017

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4 January 2020

page(s)

9174-9184

1 reference

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describes a project that uses

4 January 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC6730077/fullTextXML

inferred from PubMed Central ID database lookup

cites work

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BAX translocation is a critical event in neuronal apoptosis: regulation by neuroprotectants, BCL-2, and caspases

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Depolarization and neurotrophins converge on the phosphatidylinositol 3-kinase-Akt pathway to synergistically regulate neuronal survival

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p53 induces apoptosis by caspase activation through mitochondrial cytochrome c release.

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p73-deficient mice have neurological, pheromonal and inflammatory defects but lack spontaneous tumours

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Requirement of JNK for stress-induced activation of the cytochrome c-mediated death pathway

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Noxa, a BH3-only member of the Bcl-2 family and candidate mediator of p53-induced apoptosis

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Neurotrophin signal transduction in the nervous system

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Caspase inhibition extends the commitment to neuronal death beyond cytochrome c release to the point of mitochondrial depolarization

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An anti-apoptotic role for the p53 family member, p73, during developmental neuron death

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12 December 2020

Evidence that helix-loop-helix proteins collaborate with retinoblastoma tumor suppressor protein to regulate cortical neurogenesis

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Neuronal life and death: an essential role for the p53 family

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Induction of BIM, a proapoptotic BH3-only BCL-2 family member, is critical for neuronal apoptosis

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Dominant-negative c-Jun promotes neuronal survival by reducing BIM expression and inhibiting mitochondrial cytochrome c release

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PUMA induces the rapid apoptosis of colorectal cancer cells

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PUMA, a novel proapoptotic gene, is induced by p53

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Regulation of PTEN transcription by p53

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Neurotrophin receptor-interacting mage homologue is an inducible inhibitor of apoptosis protein-interacting protein that augments cell death

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APAF-1 is a transcriptional target of p53 in DNA damage-induced apoptosis

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Regulation of pancreatic beta-cell growth and survival by the serine/threonine protein kinase Akt1/PKBalpha

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APAF1 is a key transcriptional target for p53 in the regulation of neuronal cell death.

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Deletion of Pten in mouse brain causes seizures, ataxia and defects in soma size resembling Lhermitte-Duclos disease

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Pten regulates neuronal soma size: a mouse model of Lhermitte-Duclos disease

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12 December 2020

On Trk for retrograde signaling

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TrkA mediates developmental sympathetic neuron survival in vivo by silencing an ongoing p75NTR-mediated death signal

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12 December 2020

Transactivation-deficient Delta TA-p73 inhibits p53 by direct competition for DNA binding: implications for tumorigenesis.

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12 December 2020

p53 induces the expression of its antagonist p73 Delta N, establishing an autoregulatory feedback loop

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12 December 2020

c-jun is essential for sympathetic neuronal death induced by NGF withdrawal but not by p75 activation

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12 December 2020

p73 is required for survival and maintenance of CNS neurons

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12 December 2020

p53 has a direct apoptogenic role at the mitochondria

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12 December 2020

Cytosine arabinoside rapidly activates Bax-dependent apoptosis and a delayed Bax-independent death pathway in sympathetic neurons

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12 December 2020

Concentration-dependent regulation of neuronal gene expression by nerve growth factor

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12 December 2020

Direct activation of Bax by p53 mediates mitochondrial membrane permeabilization and apoptosis

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12 December 2020

Inhibition of p53 transactivation required for transformation by adenovirus early 1B protein

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Cell death during development of the nervous system

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Domains required for in vitro association between the cellular p53 and the adenovirus 2 E1B 55K proteins.

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An empirical method for converting nucleolar counts to neuronal numbers

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Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis

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Temporal analysis of events associated with programmed cell death (apoptosis) of sympathetic neurons deprived of nerve growth factor

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High-frequency developmental abnormalities in p53-deficient mice.

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A subset of p53-deficient embryos exhibit exencephaly

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A c-Jun dominant negative mutant protects sympathetic neurons against programmed cell death

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Altered gene expression in neurons during programmed cell death: identification of c-jun as necessary for neuronal apoptosis

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Analysis of cell cycle-related gene expression in postmitotic neurons: selective induction of Cyclin D1 during programmed cell death

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JNK1: a protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain

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Severe sensory and sympathetic neuropathies in mice carrying a disrupted Trk/NGF receptor gene.

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WAF1, a potential mediator of p53 tumor suppression

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Inhibitors of cyclin-dependent kinases promote survival of post-mitotic neuronally differentiated PC12 cells and sympathetic neurons

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12 December 2020

Adenovirus-mediated gene transfer of the tumor suppressor, p53, induces apoptosis in postmitotic neurons

1 reference

12 December 2020

Monoallelically expressed gene related to p53 at 1p36, a region frequently deleted in neuroblastoma and other human cancers

1 reference

12 December 2020

p73 is a simian [correction of human] p53-related protein that can induce apoptosis

1 reference

12 December 2020

Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery

1 reference

12 December 2020

Absence of excitotoxicity-induced apoptosis in the hippocampus of mice lacking the Jnk3 gene

1 reference

12 December 2020

Cyclin dependent kinase inhibitors and dominant negative cyclin dependent kinase 4 and 6 promote survival of NGF-deprived sympathetic neurons

1 reference

12 December 2020

Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade

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12 December 2020

Role of the Jun kinase pathway in the regulation of c-Jun expression and apoptosis in sympathetic neurons.

1 reference

12 December 2020

The p75 neurotrophin receptor mediates neuronal apoptosis and is essential for naturally occurring sympathetic neuron death

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12 December 2020

BCL-2 family: regulators of cell death

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12 December 2020

Sympathetic neuron survival and proliferation are prolonged by loss of p53 and neurofibromin

1 reference

12 December 2020

MEKK1/JNK signaling stabilizes and activates p53.

1 reference

12 December 2020

Blocking cytochrome c activity within intact neurons inhibits apoptosis.

1 reference

12 December 2020

p63, a p53 homolog at 3q27-29, encodes multiple products with transactivating, death-inducing, and dominant-negative activities

1 reference

12 December 2020

p53 is essential for developmental neuron death as regulated by the TrkA and p75 neurotrophin receptors

1 reference

12 December 2020

10.1523/JNEUROSCI.1588-04.2004

Identifiers

DOI

2 references

24 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15483136%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

1 reference

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4 January 2020

2 references

24 January 2017