Molecular basis for PP2A regulatory subunit B56alpha targeting in cardiomyocytes (Q28505912)

GOA release 2020-03-11

author name string

Naina Bhasin

1

1 reference

24 January 2017

Shane R. Cunha

2

1 reference

24 January 2017

Malkanthi Mudannayake

3

1 reference

24 January 2017

Marisa S. Gigena

4

1 reference

24 January 2017

Terry B. Rogers

5

1 reference

24 January 2017

Peter J. Mohler

American Journal of Physiology Heart and Circulatory Physiology

6

1 reference

24 January 2017

1 July 2007

1 reference

24 January 2017

1 reference

24 January 2017

293

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24 January 2017

1

1 reference

24 January 2017

H109–119

1 reference

24 January 2017

Connexin 43 downregulation and dephosphorylation in nonischemic heart failure is associated with enhanced colocalized protein phosphatase type 2A.

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00059.2007

Involvement of PP2A in viral and cellular transformation

21 January 2018

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Dilated cardiomyopathy in transgenic mice expressing a mutant A subunit of protein phosphatase 2A.

21 January 2018

1 reference

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Light-driven translocation of the protein phosphatase 2A complex regulates light/dark dephosphorylation of phosducin and rhodopsin

21 January 2018

1 reference

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Identification of specific PP2A complexes involved in human cell transformation

21 January 2018

1 reference

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Multiple sequence alignment with the Clustal series of programs

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00059.2007

Targeting and stability of Na/Ca exchanger 1 in cardiomyocytes requires direct interaction with the membrane adaptor ankyrin-B

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00059.2007

Cardiac ankyrins: Essential components for development and maintenance of excitable membrane domains in heart

21 January 2018

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A beta2 adrenergic receptor signaling complex assembled with the Ca2+ channel Cav1.2

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00059.2007

Protein phosphatase 2A is associated with class C L-type calcium channels (Cav1.2) and antagonizes channel phosphorylation by cAMP-dependent protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00059.2007

Protein kinase A and two phosphatases are components of the inositol 1,4,5-trisphosphate receptor macromolecular signaling complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00059.2007

Phospholemman-phosphorylation mediates the beta-adrenergic effects on Na/K pump function in cardiac myocytes

21 January 2018

1 reference

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Dynamic modulation of excitation-contraction coupling by protein phosphatases in rat ventricular myocytes

21 January 2018

1 reference

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Ankyrin-1 mutations are a major cause of dominant and recessive hereditary spherocytosis

21 January 2018

1 reference

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PKA, PKC, and the Protein Phosphatase 2A Influence HAND Factor Function

21 January 2018

1 reference

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Overexpression of the catalytic subunit of protein phosphatase 2A impairs cardiac function

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00059.2007

RETRACTED: L-type Ca2+ channel facilitation mediated by phosphorylation of the beta subunit by CaMKII.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00059.2007

Binding of protein phosphatase 2A to the L-type calcium channel Cav1.2 next to Ser1928, its main PKA site, is critical for Ser1928 dephosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00059.2007

Identification of a specific role for the Na,K-ATPase alpha 2 isoform as a regulator of calcium in the heart

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00059.2007

Protein phosphatase 2A: a highly regulated family of serine/threonine phosphatases implicated in cell growth and signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00059.2007

PP2A: the expected tumor suppressor

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00059.2007

Ankyrin-G coordinates assembly of the spectrin-based membrane skeleton, voltage-gated sodium channels, and L1 CAMs at Purkinje neuron initial segments

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00059.2007

Developing nodes of Ranvier are defined by ankyrin-G clustering and are independent of paranodal axoglial adhesion

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00059.2007

Calcineurin inhibits Na+/Ca2+ exchange in phenylephrine-treated hypertrophic cardiomyocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00059.2007

Lateral membrane biogenesis in human bronchial epithelial cells requires 190-kDa ankyrin-G

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00059.2007

Increased open probability of single cardiac L-type calcium channels in patients with chronic atrial fibrillation. role of phosphatase 2A.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00059.2007

Na,K-ATPase alpha1-subunit dephosphorylation by protein phosphatase 2A is necessary for its recruitment to the plasma membrane

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00059.2007

Phosphodiesterase 4D deficiency in the ryanodine-receptor complex promotes heart failure and arrhythmias

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00059.2007

B56-associated protein phosphatase 2A is required for survival and protects from apoptosis in Drosophila melanogaster

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00059.2007

Two conserved domains in regulatory B subunits mediate binding to the A subunit of protein phosphatase 2A.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00059.2007

Protein phosphatase 2A and its B56 regulatory subunit inhibit Wnt signaling in Xenopus

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00059.2007

PP2A regulates BCL-2 phosphorylation and proteasome-mediated degradation at the endoplasmic reticulum

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00059.2007

Requirement of a macromolecular signaling complex for beta adrenergic receptor modulation of the KCNQ1-KCNE1 potassium channel

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00059.2007

PKA phosphorylation dissociates FKBP12.6 from the calcium release channel (ryanodine receptor): defective regulation in failing hearts

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00059.2007

AKAP signaling complexes: getting to the heart of the matter

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00059.2007

The B56 family of protein phosphatase 2A (PP2A) regulatory subunits encodes differentiation-induced phosphoproteins that target PP2A to both nucleus and cytoplasm

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00059.2007

Ankyrins and human disease: what the electrophysiologist should know

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00059.2007

Ankyrin-B coordinates the Na/K ATPase, Na/Ca exchanger, and InsP3 receptor in a cardiac T-tubule/SR microdomain

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00059.2007

Inositol 1,4,5-trisphosphate receptor localization and stability in neonatal cardiomyocytes requires interaction with ankyrin-B

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00059.2007

The ankyrin-B C-terminal domain determines activity of ankyrin-B/G chimeras in rescue of abnormal inositol 1,4,5-trisphosphate and ryanodine receptor distribution in ankyrin-B (-/-) neonatal cardiomyocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00059.2007

Isoform specificity among ankyrins. An amphipathic alpha-helix in the divergent regulatory domain of ankyrin-b interacts with the molecular co-chaperone Hdj1/Hsp40.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00059.2007

Ankyrin-B mutation causes type 4 long-QT cardiac arrhythmia and sudden cardiac death

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00059.2007

A cardiac arrhythmia syndrome caused by loss of ankyrin-B function

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00059.2007

Ankyrin-B targets beta2-spectrin to an intracellular compartment in neonatal cardiomyocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00059.2007

Genetic profiling reveals global changes in multiple biological pathways in the hearts of Na, K-ATPase alpha 1 isoform haploinsufficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00059.2007

Protein serine/threonine phosphatases: structure, regulation, and functions in cell growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00059.2007

Genomic organization and mapping of the gene encoding the PP2A B56gamma regulatory subunit

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00059.2007

A common ankyrin-G-based mechanism retains KCNQ and NaV channels at electrically active domains of the axon

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00059.2007

The G-protein-coupled receptor phosphatase: a protein phosphatase type 2A with a distinct subcellular distribution and substrate specificity

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00059.2007

Excitation-contraction coupling in Na+-Ca2+ exchanger knockout mice: reduced transsarcolemmal Ca2+ flux.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00059.2007

Na-K-ATPase regulates tight junction permeability through occludin phosphorylation in pancreatic epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00059.2007

A positive role for the PP2A catalytic subunit in Wnt signal transduction.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00059.2007

Protein phosphatase 2A regulates apoptosis in intestinal epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00059.2007

Protein kinase A phosphorylation of the cardiac calcium release channel (ryanodine receptor) in normal and failing hearts. Role of phosphatases and response to isoproterenol

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00059.2007

Cardiac excitation-contraction coupling in the absence of Na(+) - Ca2+ exchange

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00059.2007

Targeting of Protein Kinase A by Muscle A Kinase-anchoring Protein (mAKAP) Regulates Phosphorylation and Function of the Skeletal Muscle Ryanodine Receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00059.2007

Posttranslational regulation of Drosophila PERIOD protein by protein phosphatase 2A.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00059.2007

Sodium/Calcium Exchanger (NCX1) Macromolecular Complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00059.2007

Nervous system defects of AnkyrinB (-/-) mice suggest functional overlap between the cell adhesion molecule L1 and 440-kD AnkyrinB in premyelinated axons

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00059.2007

Regulation of beta-catenin signaling by the B56 subunit of protein phosphatase 2A

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00059.2007

Actions of PP2A on the MAP kinase pathway and apoptosis are mediated by distinct regulatory subunits

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00059.2007

Protein phosphatase 2A: the Trojan Horse of cellular signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00059.2007

Regulation of cell adhesion by PP2A and SV40 small tumor antigen: an important link to cell transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00059.2007

Critical role for protein phosphatase 2A heterotrimers in mammalian cell survival.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00059.2007

Identification of a novel protein phosphatase 2A regulatory subunit highly expressed in muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00059.2007

Ankyrin-B is required for intracellular sorting of structurally diverse Ca2+ homeostasis proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00059.2007

Protein phosphatase 2A: a panoply of enzymes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00059.2007

A signaling complex of Ca2+-calmodulin-dependent protein kinase IV and protein phosphatase 2A.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00059.2007

Protein phosphatase 2A enhances the proapoptotic function of Bax through dephosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00059.2007

Structure of the protein phosphatase 2A holoenzyme

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00059.2007

The B56alpha regulatory subunit of protein phosphatase 2A is a target for regulation by double-stranded RNA-dependent protein kinase PKR

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00059.2007

PP2A:B56ϵ is required for Wnt/β-catenin signaling during embryonic development

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00059.2007

Distinct roles for PP1 and PP2A in the Neurospora circadian clock

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00059.2007

The cardiac-specific nuclear delta(B) isoform of Ca2+/calmodulin-dependent protein kinase II induces hypertrophy and dilated cardiomyopathy associated with increased protein phosphatase 2A activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00059.2007

AnkyrinG is required for clustering of voltage-gated Na channels at axon initial segments and for normal action potential firing

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00059.2007

Protein phosphatase 2A is essential for the activation of Ca2+-activated K+ currents by cGMP-dependent protein kinase in tracheal smooth muscle and Chinese hamster ovary cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00059.2007