Nf1 deficiency causes Ras-mediated granulocyte/macrophage colony stimulating factor hypersensitivity and chronic myeloid leukaemia (Q28505914)

24 January 2017

title

Nf1 deficiency causes Ras-mediated granulocyte/macrophage colony stimulating factor hypersensitivity and chronic myeloid leukaemia (English)

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24 January 2017

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GOA release 2020-03-11

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D. A. Largaespada

1

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24 January 2017

C. I. Brannan

series ordinal

2

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24 January 2017

N. A. Jenkins

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3

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24 January 2017

N. G. Copeland

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4

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24 January 2017

language of work or name

English

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publication date

1 February 1996

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24 January 2017

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24 January 2017

volume

12

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24 January 2017

issue

2

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24 January 2017

page(s)

137–143

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Tumour predisposition in mice heterozygous for a targeted mutation in Nf1

24 January 2017

cites work

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Aberrant regulation of ras proteins in malignant tumour cells from type 1 neurofibromatosis patients

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Neurofibromin can inhibit Ras-dependent growth by a mechanism independent of its GTPase-accelerating function

21 April 2017

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Loss of the normal NF1 allele from the bone marrow of children with type 1 neurofibromatosis and malignant myeloid disorders

21 January 2018

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Evi-2, a common integration site involved in murine myeloid leukemogenesis

21 January 2018

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Transgenic mice expressing a hemopoietic growth factor gene (GM-CSF) develop accumulations of macrophages, blindness, and a fatal syndrome of tissue damage

21 January 2018

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Abnormal regulation of mammalian p21ras contributes to malignant tumor growth in von Recklinghausen (type 1) neurofibromatosis

21 January 2018

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Neurofibromatosis type 1 gene mutations in neuroblastoma

21 January 2018

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Tumorigenesis by slow-transforming retroviruses--an update

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BCR-ABL-induced oncogenesis is mediated by direct interaction with the SH2 domain of the GRB-2 adaptor protein

21 January 2018

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Neurofibromatosis and cancer.

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7 January 2021

Neurofibromatosis and childhood leukemia

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7 January 2021

The neurofibromatosis type 1 gene and its protein product, neurofibromin.

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ras oncogenes: their role in neoplasia

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7 January 2021

Inactivation of the NF1 gene in human melanoma and neuroblastoma cell lines without impaired regulation of GTP.Ras

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7 January 2021

Retroviral integration at the Evi-2 locus in BXH-2 myeloid leukemia cell lines disrupts Nf1 expression without changes in steady-state Ras-GTP levels

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7 January 2021

Targeted disruption of the neurofibromatosis type-1 gene leads to developmental abnormalities in heart and various neural crest-derived tissues

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7 January 2021

Density distribution analysis ofIn vivo andIn vitro colony forming cells in developing fetal liver

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7 January 2021

Subacute and chronic myelomonocytic leukemia in children (juvenile CML). Clinical and hematologic observations, and identification of prognostic factors

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7 January 2021

Involvement of ras p21 protein in signal-transduction pathways from interleukin 2, interleukin 3, and granulocyte/macrophage colony-stimulating factor, but not from interleukin 4

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7 January 2021

RAS gene mutations in acute and chronic myelocytic leukemias, chronic myeloproliferative disorders, and myelodysplastic syndromes

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7 January 2021

Bcr-Abl oncoproteins bind directly to activators of the Ras signalling pathway

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7 January 2021

Identifiers

DOI

10.1038/NG0296-137

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