Adult hematopoietic stem and progenitor cells require either Lyl1 or Scl for survival (Q28506077)

24 January 2017

title

Adult hematopoietic stem and progenitor cells require either Lyl1 or Scl for survival (English)

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T cell acute lymphocytic leukemia 1

24 January 2017

main subject

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GOA release 2020-03-11

Fred Sablitzky

3

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author name string

George P. Souroullas

1

1 reference

24 January 2017

Jessica M. Salmon

2

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24 January 2017

David J. Curtis

4

1 reference

24 January 2017

Margaret A. Goodell

5

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24 January 2017

language of work or name

English

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publication date

6 February 2009

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24 January 2017

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24 January 2017

volume

4

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24 January 2017

issue

2

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24 January 2017

page(s)

180–186

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Id2 intrinsically regulates lymphoid and erythroid development via interaction with different target proteins

24 January 2017

cites work

1 reference

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Hematopoietic fingerprints: an expression database of stem cells and their progeny

19 March 2017

1 reference

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Runx genes are direct targets of Scl/Tal1 in the yolk sac and fetal liver

19 March 2017

1 reference

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Gata2, Fli1, and Scl form a recursively wired gene-regulatory circuit during early hematopoietic development

19 March 2017

1 reference

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Aberrant mast-cell differentiation in mice lacking the stem-cell leukemia gene

19 March 2017

1 reference

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The SCL relative LYL-1 is required for fetal and adult hematopoietic stem cell function and B-cell differentiation

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2672304

SCL is required for normal function of short-term repopulating hematopoietic stem cells

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2672304

The critical regulator of embryonic hematopoiesis, SCL, is vital in the adult for megakaryopoiesis, erythropoiesis, and lineage choice in CFU-S12

19 March 2017

1 reference

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Helix-loop-helix proteins LYL1 and E2a form heterodimeric complexes with distinctive DNA-binding properties in hematolymphoid cells

19 March 2017

1 reference

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Specific in vivo association between the bHLH and LIM proteins implicated in human T cell leukemia

19 March 2017

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Absence of blood formation in mice lacking the T-cell leukaemia oncoprotein tal-1/SCL

19 March 2017

1 reference

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Absence of yolk sac hematopoiesis from mice with a targeted disruption of the scl gene

19 March 2017

1 reference

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Inducible gene targeting in mice

19 March 2017

1 reference

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Balance between Id and E proteins regulates myeloid-versus-lymphoid lineage decisions

7 April 2017

1 reference

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The paralogous hematopoietic regulators Lyl1 and Scl are coregulated by Ets and GATA factors, but Lyl1 cannot rescue the early Scl-/- phenotype.

29 September 2017

1 reference

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Disruption of differentiation in human cancer: AML shows the way.

29 September 2017

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Gene expression signatures define novel oncogenic pathways in T cell acute lymphoblastic leukemia

29 September 2017

1 reference

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The function of E- and Id proteins in lymphocyte development

29 September 2017

1 reference

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Intertwining proteins in thymocyte development and cancer

29 September 2017

1 reference

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Specification of hematopoietic and vascular development by the bHLH transcription factor SCL without direct DNA binding

29 September 2017

1 reference

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Characterization of hematopoietic progenitor cells that express the transcription factor SCL, using a lacZ "knock-in" strategy

29 September 2017

1 reference

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Transcription factor SCL is required for c-kit expression and c-Kit function in hemopoietic cells.

29 September 2017

1 reference

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The transcriptional control of hematopoiesis

29 September 2017

1 reference

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Oncogenic transcription factors in the human acute leukemias

29 September 2017

1 reference

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lyl-1 and tal-1/scl, two genes encoding closely related bHLH transcription factors, display highly overlapping expression patterns during cardiovascular and hematopoietic ontogeny.

2 June 2018

1 reference

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Haematopoietic stem cells retain long-term repopulating activity and multipotency in the absence of stem-cell leukaemia SCL/tal-1 gene

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2672304

Overlapping functions of the myogenic bHLH genes MRF4 and MyoD revealed in double mutant mice.

27 November 2018

1 reference

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Chromosomal translocations in human cancer.

27 November 2018

1 reference

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10.1016/J.STEM.2009.01.001

27 November 2018

Identifiers

DOI

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PMC publication ID

2672304

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1 reference