Bax regulates primary necrosis through mitochondrial dynamics (Q28506109)

Gene Ontology release 2020-05-02

Gene Ontology ID

GO:1902445

BCL2-associated X protein

1 reference

GOA release 2020-03-11

Mitofusin 2

1 reference

GOA release 2020-03-11

Dynamin 1-like

1 reference

GOA release 2020-03-11

1 reference

8

John W. Calvert

John W

Calvert

1 reference

24 January 2017

3

An-Chi Wei

An-Chi

Wei

1 reference

24 January 2017

10

Craig B

Thompson

Craig B. Thompson

1 reference

24 January 2017

Russell S. Whelan

1

Russell S

Whelan

1 reference

24 January 2017

Klitos Konstantinidis

2

Klitos

Konstantinidis

1 reference

24 January 2017

Yun Chen

4

Yun

Chen

1 reference

24 January 2017

Denis E. Reyna

5

Denis E

Reyna

1 reference

24 January 2017

Saurabh Jha

6

Saurabh

Jha

1 reference

24 January 2017

Ying Yang

7

Ying

Yang

1 reference

24 January 2017

Tullia Lindsten

9

Tullia

Lindsten

1 reference

24 January 2017

Michael T. Crow

11

Michael T

Crow

1 reference

24 January 2017

Evripidis Gavathiotis

12

Evripidis

Gavathiotis

1 reference

24 January 2017

Gerald W. Dorn

13

Gerald W 2nd

Dorn

1 reference

24 January 2017

Brian O'Rourke

14

Brian

O'Rourke

1 reference

24 January 2017

Richard N. Kitsis

15

Richard N

Proceedings of the National Academy of Sciences of the United States of America

Kitsis

1 reference

24 January 2017

language of work or name

English

0 references

publication date

24 April 2012

1 reference

24 January 2017

1 reference

24 January 2017

109

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24 January 2017

6566–6571

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24 January 2017

17

1 reference

24 January 2017

Analysis of the interactions between the C-terminal cytoplasmic domains of KCNQ1 and KCNE1 channel subunits

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340068

BAX activation is initiated at a novel interaction site

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340068

Role of Bax and Bak in mitochondrial morphogenesis

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340068

Cyclophilin D is a component of mitochondrial permeability transition and mediates neuronal cell death after focal cerebral ischemia

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340068

Essential role of BAX,BAK in B cell homeostasis and prevention of autoimmune disease

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340068

Loss of cyclophilin D reveals a critical role for mitochondrial permeability transition in cell death

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340068

Cyclophilin D-dependent mitochondrial permeability transition regulates some necrotic but not apoptotic cell death

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340068

Association of Bax and Bak homo-oligomers in mitochondria. Bax requirement for Bak reorganization and cytochrome c release

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340068

Proapoptotic BAX and BAK: a requisite gateway to mitochondrial dysfunction and death

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340068

Bax oligomerization is required for channel-forming activity in liposomes and to trigger cytochrome c release from mitochondria

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340068

Enforced dimerization of BAX results in its translocation, mitochondrial dysfunction and apoptosis

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340068

Mitochondrial fusion is essential for organelle function and cardiac homeostasis

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340068

Mitochondria in apoptosis: Bcl-2 family members and mitochondrial dynamics.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340068

Exercise protects against myocardial ischemia-reperfusion injury via stimulation of β(3)-adrenergic receptors and increased nitric oxide signaling: role of nitrite and nitrosothiols

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340068

Programmed necrosis, not apoptosis, in the heart

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340068

The soluble form of Bax regulates mitochondrial fusion via MFN2 homotypic complexes

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340068

Mitofusin-2 maintains mitochondrial structure and contributes to stress-induced permeability transition in cardiac myocytes

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340068

The science of stroke: mechanisms in search of treatments

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340068

Inhibiting mitochondrial fission protects the heart against ischemia/reperfusion injury

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340068

29 September 2017

The BCL-2 family reunion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340068

Cell death in the pathogenesis of heart disease: mechanisms and significance

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340068

Stepwise activation of BAX and BAK by tBID, BIM, and PUMA initiates mitochondrial apoptosis.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340068

Chemical inhibition of the mitochondrial division dynamin reveals its role in Bax/Bak-dependent mitochondrial outer membrane permeabilization

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340068

Functions and dysfunctions of mitochondrial dynamics

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340068

A three-helix homo-oligomerization domain containing BH3 and BH1 is responsible for the apoptotic activity of Bax.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340068

Cell death by necrosis: towards a molecular definition

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340068

Necrotic death as a cell fate

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340068

Drp-1-dependent division of the mitochondrial network blocks intraorganellar Ca2+ waves and protects against Ca2+-mediated apoptosis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340068

Mitochondrial Ca2+ influx and efflux rates in guinea pig cardiac mitochondria: low and high affinity effects of cyclosporine A

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340068

The coordinate release of cytochrome c during apoptosis is rapid, complete and kinetically invariant

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3340068

Bax ablation protects against myocardial ischemia-reperfusion injury in transgenic mice

2 June 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.1201608109

A pore way to die: the role of mitochondria in reperfusion injury and cardioprotection

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.1201608109

Cardiac-Specific Deletion of Gata4 Reveals Its Requirement for Hypertrophy, Compensation, and Myocyte Viability

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.1201608109

Decoding cell death signals in inflammation and immunity

21 January 2018

1 reference

12 December 2020

Functional consequences of the sustained or transient activation by Bax of the mitochondrial permeability transition pore

1 reference

12 December 2020

Fas pathway is a critical mediator of cardiac myocyte death and MI during ischemia-reperfusion in vivo

1 reference

12 December 2020

Overexpression of BCL-2 in transgenic mice protects neurons from naturally occurring cell death and experimental ischemia

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.1201608109

1 reference

4439851

ADS bibcode

2012PNAS..109.6566W

0 references

4439851

1 reference

1 reference

1 reference