SIRT4 coordinates the balance between lipid synthesis and catabolism by repressing malonyl CoA decarboxylase (Q28506154)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23746352%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

title

SIRT4 coordinates the balance between lipid synthesis and catabolism by repressing malonyl CoA decarboxylase (English)

2 references

24 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23746352%20AND%20SRC:MED&resulttype=core&format=json

Malonyl-CoA decarboxylase

2 March 2020

main subject

1 reference

GOA release 2020-03-11

Sirtuin 4

1 reference

GOA release 2020-03-11

author

Asish K Saha

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23746352%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

Noah Dephoure

7

1 reference

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2 March 2020

Scott B Lovitch

11

1 reference

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2 March 2020

Deborah M Muoio

16

1 reference

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2 March 2020

Neil B Ruderman

17

1 reference

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2 March 2020

15

Steven P Gygi

1 reference

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2 March 2020

14

Clemens Steegborn

2 references

24 January 2017

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2 March 2020

12

Arlene H Sharpe

1 reference

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2 March 2020

18

Marcia C Haigis

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23746352%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

author name string

Gaëlle Laurent

1

2 references

24 January 2017

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2 March 2020

Michael Davies

5

2 references

24 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23746352%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

Frank Fischer

8

2 references

24 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23746352%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

Gina Boanca

9

2 references

24 January 2017

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2 March 2020

Bhavapriya Vaitheesvaran

10

2 references

24 January 2017

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2 March 2020

Natalie J German

2

1 reference

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2 March 2020

Vincent C J de Boer

4

1 reference

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2 March 2020

Timothy R Koves

6

1 reference

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2 March 2020

Irwin J Kurland

13

1 reference

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2 March 2020

publication date

1 June 2013

1 reference

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2 March 2020

2 references

24 January 2017

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2 March 2020

volume

50

2 references

24 January 2017

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2 March 2020

page(s)

686-698

1 reference

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2 March 2020

issue

5

2 references

24 January 2017

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Compromised mitochondrial fatty acid synthesis in transgenic mice results in defective protein lipoylation and energy disequilibrium

2 March 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3721068

SIRT7 links H3K18 deacetylation to maintenance of oncogenic transformation

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3721068

Sirtuins as regulators of metabolism and healthspan

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3721068

Sirt5 is a NAD-dependent protein lysine demalonylase and desuccinylase

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3721068

The first identification of lysine malonylation substrates and its regulatory enzyme

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3721068

SIRT4 regulates fatty acid oxidation and mitochondrial gene expression in liver and muscle cells

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3721068

Regulation of cellular metabolism by protein lysine acetylation

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3721068

The histone deacetylase Sirt6 regulates glucose homeostasis via Hif1alpha

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3721068

SIRT5 Deacetylates carbamoyl phosphate synthetase 1 and regulates the urea cycle

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3721068

AMPK and PPARdelta agonists are exercise mimetics

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3721068

Regulation of insulin secretion by SIRT4, a mitochondrial ADP-ribosyltransferase

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3721068

SIRT4 inhibits glutamate dehydrogenase and opposes the effects of calorie restriction in pancreatic beta cells

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3721068

The human silent information regulator (Sir)2 homologue hSIRT3 is a mitochondrial nicotinamide adenine dinucleotide-dependent deacetylase

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3721068

Acetylation of metabolic enzymes coordinates carbon source utilization and metabolic flux

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3721068

Acetylation of malate dehydrogenase 1 promotes adipogenic differentiation via activating its enzymatic activity

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3721068

Excessive hepatic mitochondrial TCA cycle and gluconeogenesis in humans with nonalcoholic fatty liver disease

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3721068

Mitochondrial sirtuins in the regulation of mitochondrial activity and metabolic adaptation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3721068

The fasted/fed mouse metabolic acetylome: N6-acetylation differences suggest acetylation coordinates organ-specific fuel switching

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3721068

Transcriptional control of adipose lipid handling by IRF4

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3721068

Sensing of energy and nutrients by AMP-activated protein kinase.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3721068

Malonyl-CoA, a key signaling molecule in mammalian cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3721068

Mitochondrial overload and incomplete fatty acid oxidation contribute to skeletal muscle insulin resistance

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3721068

Regulation of lipolysis in adipocytes

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3721068

Skeletal muscle and heart LKB1 deficiency causes decreased voluntary running and reduced muscle mitochondrial marker enzyme expression in mice

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3721068

AMP-activated protein kinase signaling in metabolic regulation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3721068

Signaling pathways in skeletal muscle remodeling

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3721068

Exercise training decreases the concentration of malonyl-CoA and increases the expression and activity of malonyl-CoA decarboxylase in human muscle

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3721068

Malonyl-CoA decarboxylase (MCD) is differentially regulated in subcellular compartments by 5'AMP-activated protein kinase (AMPK). Studies using H9c2 cells overexpressing MCD and AMPK by adenoviral gene transfer technique

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3721068

Malonyl-CoA and AMP-activated protein kinase: an expanding partnership

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3721068

AMPK as a metabolic switch in rat muscle, liver and adipose tissue after exercise.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3721068

Quantitation of basal endogenous glucose production in Type II diabetes: importance of the volume of distribution

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3721068

Malonyl-CoA decarboxylase is not a substrate of AMP-activated protein kinase in rat fast-twitch skeletal muscle or an islet cell line

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3721068

Measurement of fractional lipid synthesis using deuterated water (2H2O) and mass isotopomer analysis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3721068

The activation of specific gene transcription in the adipose conversion of 3T3 cells

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3721068

Hepatic malonyl-CoA levels of fed, fasted and diabetic rats as measured using a simple radioisotopic assay

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3721068

Endurance training attenuates the decrease in skeletal muscle malonyl-CoA with exercise.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3721068

Investigating the ADP-ribosyltransferase activity of sirtuins with NAD analogues and 32P-NAD.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3721068

Radiochemical malonyl-CoA decarboxylase assay: activity and subcellular distribution in heart and skeletal muscle

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3721068

Activation of Malonyl-CoA Decarboxylase in Rat Skeletal Muscle by Contraction and the AMP-activated Protein Kinase Activator 5-Aminoimidazole-4-carboxamide-1-β-d-ribofuranoside

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3721068

Fatty acid transport and utilization for the developing brain

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3721068

Exercise diminishes the activity of acetyl-CoA carboxylase in human muscle

27 November 2018

1 reference

12 December 2020

Purification and crystallization of rat liver fatty acid synthetase

1 reference

12 December 2020

A malonyl-CoA fuel-sensing mechanism in muscle: effects of insulin, glucose, and denervation

1 reference

12 December 2020

Mass spectrometric identification of K210 essential for rat malonyl-CoA decarboxylase catalysis

1 reference

12 December 2020

Preparation, culture, and immortalization of mouse embryonic fibroblasts

1 reference

12 December 2020

10.1016/J.MOLCEL.2013.05.012

Identifiers

DOI

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23746352%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

1 reference

2 references

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2 March 2020

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23746352%20AND%20SRC:MED&resulttype=core&format=json