Inhibition of beta 2 integrin receptor and Syk kinase signaling in monocytes by the Src family kinase Fgr (Q28507457)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11672534%20AND%20SRC:MED&resulttype=core&format=json

13 November 2019

title

Inhibition of beta 2 integrin receptor and Syk kinase signaling in monocytes by the Src family kinase Fgr (English)

2 references

24 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11672534%20AND%20SRC:MED&resulttype=core&format=json

13 November 2019

main subject

Spleen tyrosine kinase

1 reference

FGR proto-oncogene, Src family tyrosine kinase

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

author

Robert L. Geahlen

4

1 reference

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13 November 2019

Victor Tybulewicz

6

1 reference

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13 November 2019

author name string

C M Vines

1

1 reference

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13 November 2019

J W Potter

2

1 reference

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13 November 2019

Y Xu

3

1 reference

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13 November 2019

P S Costello

5

1 reference

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13 November 2019

C A Lowell

7

1 reference

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13 November 2019

P W Chang

8

1 reference

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13 November 2019

H D Gresham

9

1 reference

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13 November 2019

C L Willman

10

1 reference

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13 November 2019

language of work or name

English

0 references

publication date

1 October 2001

2 references

24 January 2017

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13 November 2019

2 references

24 January 2017

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13 November 2019

volume

15

2 references

24 January 2017

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13 November 2019

issue

4

2 references

24 January 2017

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13 November 2019

page(s)

507-519

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Beta 2 integrin-dependent protein tyrosine phosphorylation and activation of the FGR protein tyrosine kinase in human neutrophils

13 November 2019

cites work

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Syk tyrosine kinase required for mouse viability and B-cell development

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Syk tyrosine kinase is required for immunoreceptor tyrosine activation motif-dependent actin assembly

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A critical role for Syk in signal transduction and phagocytosis mediated by Fcgamma receptors on macrophages

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Functional and physical interactions of Syk family kinases with the Vav proto-oncogene product

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syk kinase activation by a src kinase-initiated activation loop phosphorylation chain reaction

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7 January 2021

Selective regulation of integrin--cytoskeleton interactions by the tyrosine kinase Src.

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7 January 2021

Fcgamma receptor-mediated phagocytosis in macrophages lacking the Src family tyrosine kinases Hck, Fgr, and Lyn.

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Identification of the major sites of autophosphorylation of the murine protein-tyrosine kinase Syk

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7 January 2021

MCP-1 and IL-8 trigger firm adhesion of monocytes to vascular endothelium under flow conditions

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Negative regulation of phagocytosis in murine macrophages by the Src kinase family member, Fgr.

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Translocation of the FGR protein-tyrosine kinase as a consequence of neutrophil activation.

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Association of immunoglobulin G Fc receptor II with Src-like protein-tyrosine kinase Fgr in neutrophils

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7 January 2021

The Syk protein tyrosine kinase is essential for Fcgamma receptor signaling in macrophages and neutrophils

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7 January 2021

Integrin-mediated tyrosine phosphorylation and cytokine message induction in monocytic cells. A possible signaling role for the Syk tyrosine kinase.

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7 January 2021

Structure and function of the cytoplasmic domain of band 3: center of erythrocyte membrane-peripheral protein interactions

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7 January 2021

Functional overlap in the src gene family: inactivation of hck and fgr impairs natural immunity

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7 January 2021

Deficiency of Src family kinases p59/61hck and p58c-fgr results in defective adhesion-dependent neutrophil functions

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7 January 2021

Resistance to endotoxic shock and reduced neutrophil migration in mice deficient for the Src-family kinases Hck and Fgr

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7 January 2021

Monocyte rolling, arrest and spreading on IL-4-activated vascular endothelium under flow is mediated via sequential action of L-selectin, beta 1-integrins, and beta 2-integrins

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7 January 2021

A beta 1 integrin signaling pathway involving Src-family kinases, Cbl and PI-3 kinase is required for macrophage spreading and migration

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7 January 2021

Identification of a novel integrin signaling pathway involving the kinase Syk and the guanine nucleotide exchange factor Vav1

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Isolation and characterization of a cloned growth factor dependent macrophage cell line, BAC1.2F5.

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Integrin-ligand binding properties govern cell migration speed through cell-substratum adhesiveness

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Cellular functions regulated by Src family kinases

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Perinatal lethality and blocked B-cell development in mice lacking the tyrosine kinase Syk

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7 January 2021

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7 January 2021

Phosphorylation of Syk activation loop tyrosines is essential for Syk function. An in vivo study using a specific anti-Syk activation loop phosphotyrosine antibody

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Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11672534%20AND%20SRC:MED&resulttype=core&format=json

13 November 2019

2 references

24 January 2017