Identification of a novel integrin signaling pathway involving the kinase Syk and the guanine nucleotide exchange factor Vav1 (Q77649221)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9843681%20AND%20SRC:MED&resulttype=core&format=json

7 December 2019

title

Identification of a novel integrin signaling pathway involving the kinase Syk and the guanine nucleotide exchange factor Vav1 (English)

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7 December 2019

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C K Miranti

1

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7 December 2019

L Leng

2

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7 December 2019

P Maschberger

3

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7 December 2019

J S Brugge

4

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7 December 2019

S J Shattil

5

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7 December 2019

language of work or name

English

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publication date

1 December 1998

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7 December 2019

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9843681%20AND%20SRC:MED&resulttype=core&format=json

7 December 2019

volume

8

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7 December 2019

issue

24

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7 December 2019

page(s)

1289-1299

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Integrins and signal transduction pathways: the road taken

7 December 2019

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2807%2900559-3

7 January 2021

Regulation of the pp72syk protein tyrosine kinase by platelet integrin alpha IIb beta 3

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2807%2900559-3

7 January 2021

Complementary roles for receptor clustering and conformational change in the adhesive and signaling functions of integrin alphaIIb beta3

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2807%2900559-3

7 January 2021

Integrin-mediated tyrosine phosphorylation and cytokine message induction in monocytic cells. A possible signaling role for the Syk tyrosine kinase.

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2807%2900559-3

7 January 2021

Thrombin receptor activation and integrin engagement stimulate tyrosine phosphorylation of the proto-oncogene product, p95vav, in platelets

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2807%2900559-3

7 January 2021

Antibody-induced engagement of beta 2 integrins on adherent human neutrophils triggers activation of p21ras through tyrosine phosphorylation of the protooncogene product Vav

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2807%2900559-3

7 January 2021

Redistribution of activated pp60c-src to integrin-dependent cytoskeletal complexes in thrombin-stimulated platelets

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2807%2900559-3

7 January 2021

Role of actin polymerization and adhesion to extracellular matrix in Rac- and Rho-induced cytoskeletal reorganization

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2807%2900559-3

7 January 2021

The small GTP-binding proteins Rac1 and Cdc42 regulate the activity of the JNK/SAPK signaling pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2807%2900559-3

7 January 2021

Integrin signalling and tyrosine phosphorylation: just the FAKs?

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2807%2900559-3

7 January 2021

Multiple Grb2-mediated integrin-stimulated signaling pathways to ERK2/mitogen-activated protein kinase: summation of both c-Src- and focal adhesion kinase-initiated tyrosine phosphorylation events

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2807%2900559-3

7 January 2021

A requirement for caveolin-1 and associated kinase Fyn in integrin signaling and anchorage-dependent cell growth

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2807%2900559-3

7 January 2021

Tyrosine kinases in activation of the MAP kinase cascade by G-protein-coupled receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2807%2900559-3

7 January 2021

Reconstitution of T cell antigen receptor-induced Erk2 kinase activation in Lck-negative JCaM1 cells by Syk

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2807%2900559-3

7 January 2021

Association of a p95 Vav-containing Signaling Complex with the FcϵRI γ Chain in the RBL-2H3 Mast Cell Line

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2807%2900559-3

7 January 2021

Cbl: complex formation and functional implications

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2807%2900559-3

7 January 2021

Oncogenic forms of Cbl abrogate the anchorage requirement but not the growth factor requirement for proliferation

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2807%2900559-3

7 January 2021

p120cbl is a major substrate of tyrosine phosphorylation upon B cell antigen receptor stimulation and interacts in vivo with Fyn and Syk tyrosine kinases, Grb2 and Shc adaptors, and the p85 subunit of phosphatidylinositol 3-kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2807%2900559-3

7 January 2021

Phosphatidylinositol 3-kinase is required for integrin-stimulated AKT and Raf-1/mitogen-activated protein kinase pathway activation

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2807%2900559-3

7 January 2021

Biphasic activation of PKBalpha/Akt in platelets. Evidence for stimulation both by phosphatidylinositol 3,4-bisphosphate, produced via a novel pathway, and by phosphatidylinositol 3,4,5-trisphosphate

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2807%2900559-3

7 January 2021

D3 phosphoinositides and outside-in integrin signaling by glycoprotein IIb-IIIa mediate platelet actin assembly and filopodial extension induced by phorbol 12-myristate 13-acetate

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2807%2900559-3

7 January 2021

Integrin cytoplasmic domains: mediators of cytoskeletal linkages and extra- and intracellular initiated transmembrane signaling

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2807%2900559-3

7 January 2021

Focal adhesion assembly

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2807%2900559-3

7 January 2021

Integrin-mediated tyrosine phosphorylation of SHPS-1 and its association with SHP-2. Roles of Fak and Src family kinases

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2807%2900559-3

7 January 2021

Activation of Rac and Cdc42 by integrins mediates cell spreading

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2807%2900559-3

7 January 2021

Rho, rac, and cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2807%2900559-3

7 January 2021

Integrin-mediated signals regulated by members of the rho family of GTPases

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2807%2900559-3

7 January 2021

Calpain regulation of cytoskeletal signaling complexes in von Willebrand factor-stimulated platelets. Distinct roles for glycoprotein Ib-V-IX and glycoprotein IIb-IIIa (integrin alphaIIbbeta3) in von Willebrand factor-induced signal transduction

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2807%2900559-3

7 January 2021

Thrombin receptor ligation and activated rac uncap actin filament barbed ends through phosphoinositide synthesis in permeabilized human platelets

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2807%2900559-3

7 January 2021

Signalling through the lipid products of phosphoinositide-3-OH kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2807%2900559-3

7 January 2021

Role of substrates and products of PI 3-kinase in regulating activation of Rac-related guanosine triphosphatases by Vav

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2807%2900559-3

7 January 2021

Regulation of beta 1-integrin-mediated cell adhesion by the Cbl adaptor protein

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2807%2900559-3

7 January 2021

A beta 1 integrin signaling pathway involving Src-family kinases, Cbl and PI-3 kinase is required for macrophage spreading and migration

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2807%2900559-3

7 January 2021

Coordinated regulation of the tyrosine phosphorylation of Cbl by Fyn and Syk tyrosine kinases

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2807%2900559-3

7 January 2021

The protein kinase encoded by the Akt proto-oncogene is a target of the PDGF-activated phosphatidylinositol 3-kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2807%2900559-3

7 January 2021

[29] Assay and expression of mitogen-activated protein kinase, MAP kinase kinase, and Raf

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2807%2900559-3

7 January 2021

Vav is a regulator of cytoskeletal reorganization mediated by the T-cell receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2807%2900559-3

7 January 2021

10.1016/S0960-9822(07)00559-3

Identifiers

DOI

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9843681%20AND%20SRC:MED&resulttype=core&format=json

7 December 2019

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