PTH/PTHrP receptor delays chondrocyte hypertrophy via both Runx2-dependent and -independent pathways (Q28508903)

Parathyroid hormone 1 receptor

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

author name string

Jun Guo

1

1 reference

24 January 2017

Ung-Il Chung

2

1 reference

24 January 2017

Dehong Yang

3

1 reference

24 January 2017

Gerard Karsenty

4

1 reference

24 January 2017

F. Richard Bringhurst

5

1 reference

24 January 2017

Henry M. Kronenberg

Osf2/Cbfa1: a transcriptional activator of osteoblast differentiation

6

1 reference

24 January 2017

language of work or name

English

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publication date

1 April 2006

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24 January 2017

Developmental Biology

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24 January 2017

292

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24 January 2017

1

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24 January 2017

116–128

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24 January 2017

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2005.12.044

A Cbfa1-dependent genetic pathway controls bone formation beyond embryonic development

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The PTH/PTHrP receptor can delay chondrocyte hypertrophy in vivo without activating phospholipase C

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1 reference

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The chondrogenic transcription factor Sox9 is a target of signaling by the parathyroid hormone-related peptide in the growth plate of endochondral bones

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Maturational disturbance of chondrocytes in Cbfa1-deficient mice

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Structural alterations in the transcription factor PEBP2/CBF linked to four different types of leukemia

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1 reference

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Runx2 expression and action in chondrocytes are regulated by retinoid signaling and parathyroid hormone-related peptide (PTHrP).

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1 reference

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Lethal skeletal dysplasia from targeted disruption of the parathyroid hormone-related peptide gene

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1 reference

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Targeted disruption of Cbfa1 results in a complete lack of bone formation owing to maturational arrest of osteoblasts

7 January 2021

1 reference

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PTH/PTHrP receptor in early development and Indian hedgehog-regulated bone growth

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1 reference

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AML1, AML2, and AML3, the human members of the runt domain gene-family: cDNA structure, expression, and chromosomal localization

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Causal relationship between the loss of RUNX3 expression and gastric cancer

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Parathyroid hormone-related peptide (PTHrP) inhibits Runx2 expression through the PKA signaling pathway.

7 January 2021

1 reference

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The cyclin-dependent kinase inhibitor p57(Kip2) mediates proliferative actions of PTHrP in chondrocytes

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1 reference

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Molecular cloning and characterization of PEBP2 beta, the heterodimeric partner of a novel Drosophila runt-related DNA binding protein PEBP2 alpha

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1 reference

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AML1, the target of multiple chromosomal translocations in human leukemia, is essential for normal fetal liver hematopoiesis

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1 reference

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Cbfa1, a candidate gene for cleidocranial dysplasia syndrome, is essential for osteoblast differentiation and bone development

7 January 2021

1 reference

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Upstream and downstream targets of RUNX proteins.

7 January 2021

1 reference

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Targeted expression of constitutively active receptors for parathyroid hormone and parathyroid hormone-related peptide delays endochondral bone formation and rescues mice that lack parathyroid hormone-related peptide

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1 reference

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Parathyroid hormone regulation of the rat collagenase-3 promoter by protein kinase A-dependent transactivation of core binding factor alpha1.

7 January 2021

1 reference

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Continuous expression of Cbfa1 in nonhypertrophic chondrocytes uncovers its ability to induce hypertrophic chondrocyte differentiation and partially rescues Cbfa1-deficient mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2005.12.044

The retinoblastoma protein acts as a transcriptional coactivator required for osteogenic differentiation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2005.12.044

Skeletal malformations caused by overexpression of Cbfa1 or its dominant negative form in chondrocytes

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1 reference

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Cloning and characterization of subunits of the T-cell receptor and murine leukemia virus enhancer core-binding factor

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The CBFbeta subunit is essential for CBFalpha2 (AML1) function in vivo

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Targeted overexpression of parathyroid hormone-related peptide in chondrocytes causes chondrodysplasia and delayed endochondral bone formation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2005.12.044

Runx2 and Runx3 are essential for chondrocyte maturation, and Runx2 regulates limb growth through induction of Indian hedgehog

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2005.12.044