Prostaglandin E2-EP4 signaling promotes immune inflammation through Th1 cell differentiation and Th17 cell expansion (Q28509130)

GOA release 2020-03-11

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8

Shuh Narumiya

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24 January 2017

Chengcan Yao

1

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24 January 2017

Daiji Sakata

2

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24 January 2017

Yoshiyasu Esaki

3

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24 January 2017

Youxian Li

4

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24 January 2017

Toshiyuki Matsuoka

5

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24 January 2017

Kenji Kuroiwa

6

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24 January 2017

Yukihiko Sugimoto

Positive and negative regulation of T-cell activation through kinases and phosphatases

7

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24 January 2017

language of work or name

English

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publication date

1 June 2009

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24 January 2017

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24 January 2017

15

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24 January 2017

633–640

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24 January 2017

6

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24 January 2017

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12 December 2020

Phenotypic and functional features of human Th17 cells

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12 December 2020

Receptors for prostaglandin E(2) that regulate cellular immune responses in the mouse

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12 December 2020

Prostaglandin E2 regulates Th17 cell differentiation and function through cyclic AMP and EP2/EP4 receptor signaling

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12 December 2020

Analysis of the defects responsible for the impaired regulation of EBV-induced B cell proliferation by rheumatoid arthritis lymphocytes. II. Role of monocytes and the increased sensitivity of rheumatoid arthritis lymphocytes to prostaglandin E

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12 December 2020

In vitro differentiation of dendritic cells in the presence of prostaglandin E2 alters the IL-12/IL-23 balance and promotes differentiation of Th17 cells

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12 December 2020

A genome-wide association study identifies IL23R as an inflammatory bowel disease gene

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12 December 2020

Increased release of interleukin-12p40 in MS: association with intracerebral inflammation.

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12 December 2020

Prostaglandin E receptors

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12 December 2020

Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells

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12 December 2020

Physiology and pathophysiology of prostanoid receptors

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12 December 2020

The proinflammatory effect of prostaglandin E2 in experimental inflammatory bowel disease is mediated through the IL-23-->IL-17 axis

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12 December 2020

Regulation of the immune response by prostaglandins

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12 December 2020

Novel Crohn disease locus identified by genome-wide association maps to a gene desert on 5p13.1 and modulates expression of PTGER4

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12 December 2020

Prostaglandin E2-EP4 signaling initiates skin immune responses by promoting migration and maturation of Langerhans cells.

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12 December 2020

Prostaglandin E2 synergistically with interleukin-23 favors human Th17 expansion

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12 December 2020

Differential modulation of T helper type 1 (Th1) and T helper type 2 (Th2) cytokine secretion by prostaglandin E2 critically depends on interleukin-2.

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12 December 2020

cAMP analog mapping of Epac1 and cAMP kinase. Discriminating analogs demonstrate that Epac and cAMP kinase act synergistically to promote PC-12 cell neurite extension

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12 December 2020

The immunological and genetic basis of inflammatory bowel disease

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12 December 2020

Pathogenesis and therapy of psoriasis

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12 December 2020

PI3K in lymphocyte development, differentiation and activation

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12 December 2020

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12 December 2020

Facilitation of Th1-mediated immune response by prostaglandin E receptor EP1.

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12 December 2020

A rush to judgment on Th17

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12 December 2020

The role of prostaglandin E receptor subtypes (EP1, EP2, EP3, and EP4) in bone resorption: an analysis using specific agonists for the respective EPs

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12 December 2020

Phosphoinositide kinases

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12 December 2020

Cutting edge: in vitro generated Th17 cells maintain their cytokine expression program in normal but not lymphopenic hosts.

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12 December 2020

High levels of IL-17 in rheumatoid arthritis patients: IL-15 triggers in vitro IL-17 production via cyclosporin A-sensitive mechanism

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12 December 2020

Genetic and pharmacological analysis of prostanoid receptor function

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12 December 2020

IL-6 blockade inhibits the induction of myelin antigen-specific Th17 cells and Th1 cells in experimental autoimmune encephalomyelitis

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12 December 2020

The prostaglandin receptor EP4 suppresses colitis, mucosal damage and CD4 cell activation in the gut

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12 December 2020

IL-23 drives a pathogenic T cell population that induces autoimmune inflammation

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12 December 2020

Pivotal roles of the parasite PGD2 synthase and of the host D prostanoid receptor 1 in schistosome immune evasion

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12 December 2020

Patent ductus arteriosus and neonatal death in prostaglandin receptor EP4-deficient mice

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12 December 2020

Antigen-specific T cell sensitization is impaired in IL-17-deficient mice, causing suppression of allergic cellular and humoral responses

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12 December 2020

Prostaglandin E2 inhibits production of Th1 lymphokines but not of Th2 lymphokines

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12 December 2020

Late developmental plasticity in the T helper 17 lineage

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12 December 2020

Increased expression of interleukin 17 in inflammatory bowel disease

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12 December 2020

Unravelling the pathogenesis of inflammatory bowel disease

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12 December 2020

Prostaglandins as modulators of immunity

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12 December 2020

Pharmacological PKA inhibition: all may not be what it seems

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12 December 2020

Epac proteins: multi-purpose cAMP targets

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12 December 2020

Abortive expansion of the cumulus and impaired fertility in mice lacking the prostaglandin E receptor subtype EP(2)

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12 December 2020

Psoriasis Vulgaris Lesions Contain Discrete Populations of Th1 and Th17 T Cells

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12 December 2020

IL-23: a master regulator in Crohn disease

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12 December 2020

Role of beta-arrestin 1 in the metastatic progression of colorectal cancer

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12 December 2020

Modulation of helper T cell function by prostaglandins

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12 December 2020

A human interleukin-12/23 monoclonal antibody for the treatment of psoriasis

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12 December 2020

EP2 and EP4 prostanoid receptor signaling

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12 December 2020

Interleukin-17 production in central nervous system-infiltrating T cells and glial cells is associated with active disease in multiple sclerosis

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12 December 2020

Gene-microarray analysis of multiple sclerosis lesions yields new targets validated in autoimmune encephalomyelitis

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12 December 2020

Anti-interleukin-12 antibody for active Crohn's disease

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12 December 2020

Thromboxane A2 modulates interaction of dendritic cells and T cells and regulates acquired immunity

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12 December 2020

A brief history of T(H)17, the first major revision in the T(H)1/T(H)2 hypothesis of T cell-mediated tissue damage

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12 December 2020

Sequence variants in the genes for the interleukin-23 receptor (IL23R) and its ligand (IL12B) confer protection against psoriasis.

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12 December 2020

Prostaglandin E2 impairs CD4+ T cell activation by inhibition of lck: implications in Hodgkin's lymphoma

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12 December 2020

Interferon gamma responses to myelin peptides in multiple sclerosis correlate with a new clinical measure of disease progression.

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12 December 2020

Identifiers

DOI

10.1038/NM.1968

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Consolidated OpenCitations Corpus – April 2017

Dimensions Publication ID

2341994

1052740589

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2341994

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Consolidated OpenCitations Corpus – April 2017

Consolidated OpenCitations Corpus – April 2017

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