Sequence variants in the genes for the interleukin-23 receptor (IL23R) and its ligand (IL12B) confer protection against psoriasis. (Q46147942)

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title

Sequence variants in the genes for the interleukin-23 receptor (IL23R) and its ligand (IL12B) confer protection against psoriasis (English)

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Richard C Trembath

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Francesca Capon

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Paola Di Meglio

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Jonathan N. Barker

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A David Burden

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author name string

Joanna Szaub

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Christina Dunster

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Laura Baumber

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Kirsten Timms

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Alexander Gutin

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Victor Abkevic

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Jerry Lanchbury

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Frank O Nestle

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publication date

22 June 2007

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volume

122

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issue

2

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page(s)

201-206

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https://scigraph.springernature.com/pub.10.1007/s00439-007-0397-0

1 January 2020

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cites work

A receptor for the heterodimeric cytokine IL-23 is composed of IL-12Rbeta1 and a novel cytokine receptor subunit, IL-23R

1 reference

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Recent insights into the immunopathogenesis of psoriasis provide new therapeutic opportunities

21 January 2018

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12 December 2020

Genomic DNA pooling for whole-genome association scans in complex disease: empirical demonstration of efficacy in rheumatoid arthritis

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12 December 2020

A genome-wide association study identifies IL23R as an inflammatory bowel disease gene

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12 December 2020

Identification of a major susceptibility locus on chromosome 6p and evidence for further disease loci revealed by a two stage genome-wide search in psoriasis

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12 December 2020

Analysis of RUNX1 binding site and RAPTOR polymorphisms in psoriasis: no evidence for association despite adequate power and evidence for linkage

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12 December 2020

Pedigree disequilibrium tests for multilocus haplotypes.

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12 December 2020

Genetic linkage of childhood atopic dermatitis to psoriasis susceptibility loci

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12 December 2020

Association of the T-cell regulatory gene CTLA4 with susceptibility to autoimmune disease

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12 December 2020

Combining information from common type 2 diabetes risk polymorphisms improves disease prediction

1 reference

12 December 2020

A large-scale genetic association study confirms IL12B and leads to the identification of IL23R as psoriasis-risk genes

1 reference

12 December 2020

Lack of evidence for genetic association to RUNX1 binding site at PSORS2 in different German psoriasis cohorts

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12 December 2020

An update on the genetics of psoriasis.

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12 December 2020

Genomewide scan in german families reveals evidence for a novel psoriasis-susceptibility locus on chromosome 19p13.

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12 December 2020

A putative RUNX1 binding site variant between SLC9A3R1 and NAT9 is associated with susceptibility to psoriasis

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12 December 2020

Discovery and biology of IL-23 and IL-27: related but functionally distinct regulators of inflammation

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12 December 2020

The IL-23/Th(17) axis: therapeutic targets for autoimmune inflammation

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Cohort profile: 1958 British birth cohort (National Child Development Study).

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Role of PTPN22 in type 1 diabetes and other autoimmune diseases

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Genetic analysis of PSORS2 markers in a UK dataset supports the association between RAPTOR SNPs and familial psoriasis.

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12 December 2020

The genetics of psoriasis, psoriatic arthritis and atopic dermatitis

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Searching for the major histocompatibility complex psoriasis susceptibility gene.

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A human interleukin-12/23 monoclonal antibody for the treatment of psoriasis

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Case-only design to measure gene-gene interaction.

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Accounting for decay of linkage disequilibrium in haplotype inference and missing-data imputation

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12 December 2020

Psoriasis and its management

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12 December 2020

Common variation in three genes, including a noncoding variant in CFH, strongly influences risk of age-related macular degeneration

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12 December 2020

Evidence for two psoriasis susceptibility loci (HLA and 17q) and two novel candidate regions (16q and 20p) by genome-wide scan

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12 December 2020

10.1007/S00439-007-0397-0

Identifiers

DOI

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1 January 2020

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