Polycystin 1 is required for the structural integrity of blood vessels (Q28512594)

GOA release 2020-03-11

author name string

K. Kim

1

1 reference

25 January 2017

I. Drummond

2

1 reference

25 January 2017

O. Ibraghimov-Beskrovnaya

3

1 reference

25 January 2017

K. Klinger

4

1 reference

25 January 2017

M. A. Arnaout

Proceedings of the National Academy of Sciences of the United States of America

5

1 reference

25 January 2017

language of work or name

English

0 references

publication date

15 February 2000

1 reference

25 January 2017

1 reference

25 January 2017

97

1 reference

25 January 2017

4

1 reference

25 January 2017

1731–1736

1 reference

25 January 2017

Cardiac defects and renal failure in mice with targeted mutations in Pkd2

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Pathophysiology of gene-targeted mouse models for cystic fibrosis

19 March 2017

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PDGF, TGF-beta, and heterotypic cell-cell interactions mediate endothelial cell-induced recruitment of 10T1/2 cells and their differentiation to a smooth muscle fate

19 March 2017

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Perinatal lethality with kidney and pancreas defects in mice with a targetted Pkd1 mutation

19 March 2017

1 reference

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PKD1 interacts with PKD2 through a probable coiled-coil domain

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=26504

Vascular dysmorphogenesis caused by an activating mutation in the receptor tyrosine kinase TIE2

19 March 2017

1 reference

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Requisite role of angiopoietin-1, a ligand for the TIE2 receptor, during embryonic angiogenesis

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=26504

PKD2, a gene for polycystic kidney disease that encodes an integral membrane protein

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=26504

Defective haematopoiesis and vasculogenesis in transforming growth factor-beta 1 knock out mice

19 March 2017

1 reference

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Germ-line transmission of a disrupted beta 2-microglobulin gene produced by homologous recombination in embryonic stem cells

19 March 2017

1 reference

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Targeted mutation of the DNA methyltransferase gene results in embryonic lethality

19 March 2017

1 reference

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Bilateral polycystic disease of the kidneys; a follow-up of two hundred and eighty-four patients and their families

19 March 2017

1 reference

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Identification and characterization of polycystin-2, the PKD2 gene product

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=26504

The polycystic kidney disease 1 gene product modulates Wnt signaling

29 September 2017

1 reference

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Selective increase of the permeability of polarized epithelial cell monolayers by Helicobacter pylori vacuolating toxin

29 September 2017

1 reference

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Polycystin: in vitro synthesis, in vivo tissue expression, and subcellular localization identifies a large membrane-associated protein

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=26504

A synthetic peptide corresponding to the extracellular domain of occludin perturbs the tight junction permeability barrier

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=26504

Identification and localization of polycystin, the PKD1 gene product

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=26504

Characterization and cell distribution of polycystin, the product of autosomal dominant polycystic kidney disease gene 1.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=26504

Polycystic kidney disease: hereditary and acquired.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=26504

Abnormal kidney development and hematological disorders in PDGF beta-receptor mutant mice.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=26504

Mice deficient for PDGF B show renal, cardiovascular, and hematological abnormalities

29 September 2017

1 reference

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Phenotype-dependent response of cultured aortic smooth muscle to serum mitogens

29 September 2017

1 reference

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Developing nervous tissue induces formation of blood-brain barrier characteristics in invading endothelial cells: a study using quail--chick transplantation chimeras

29 September 2017

1 reference

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Inhibition of capillary endothelial cell growth by pericytes and smooth muscle cells

29 September 2017

1 reference

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Phenotypic modulation of endothelial cells by transforming growth factor-beta depends upon the composition and organization of the extracellular matrix

29 September 2017

1 reference

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Junctional complexes and cell polarity in the urinary tubule

29 September 2017

1 reference

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Inhibition of endothelial cell movement by pericytes and smooth muscle cells: activation of a latent transforming growth factor-beta 1-like molecule by plasmin during co-culture

29 September 2017

1 reference

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The discs-large tumor suppressor gene of Drosophila encodes a guanylate kinase homolog localized at septate junctions

29 September 2017

1 reference

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Hereditary polycystic kidney disease (adult form): a microdissection study of two cases at an early stage of the disease

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=26504

Epithelial cell polarity and disease

29 September 2017

1 reference

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Blood vessel formation: what is its molecular basis?

2 June 2018

1 reference

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The C. elegans vulval induction gene lin-2 encodes a member of the MAGUK family of cell junction proteins

2 June 2018

1 reference

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Embryonic vascular development: immunohistochemical identification of the origin and subsequent morphogenesis of the major vessel primordia in quail embryos.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=26504

Germline mutations in the Wilms' tumor suppressor gene are associated with abnormal urogenital development in Denys-Drash syndrome

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=26504

Saccular intracranial aneurysms in autosomal dominant polycystic kidney disease

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=26504

Vascular expression of polycystin.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=26504

The polycystic kidney disease-1 protein, polycystin-1, binds and activates heterotrimeric G-proteins in vitro.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=26504

Occult intracranial aneurysms in polycystic kidney disease: screening with MR angiography.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=26504

The polycystic kidney disease 1 gene encodes a 14 kb transcript and lies within a duplicated region on chromosome 16. The European Polycystic Kidney Disease Consortium

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=26504

Immunolocalization of polycystin in human tissues and cultured cells

27 November 2018

1 reference

12 December 2020

Evidence for a third genetic locus for autosomal dominant polycystic kidney disease

1 reference

12 December 2020

Late onset of renal and hepatic cysts in Pkd1-targeted heterozygotes

1 reference

12 December 2020

Autosomal dominant polycystic kidney disease

1 reference

12 December 2020

Somatic inactivation of Pkd2 results in polycystic kidney disease

1 reference

12 December 2020

Polycystic kidney disease: The complete structure of the PKD1 gene and its protein

1 reference

12 December 2020

Renal histology in polycystic kidney disease with incipient and advanced renal failure

1 reference

12 December 2020

Value of magnetic resonance angiography for the detection of intracranial aneurysms in autosomal dominant polycystic kidney disease

1 reference

12 December 2020

Role of the pericyte in wound healing. An ultrastructural study

1 reference

12 December 2020

Cellular localization and tissue distribution of polycystin-1

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.040550097

1 reference

1290304

ADS bibcode

2000PNAS...97.1731K

0 references

1290304

1 reference

1 reference

1 reference