Reversible suppression of an essential gene in adult mice using transgenic RNA interference (Q28512942)

GOA release 2020-03-11

1 reference

Katherine McJunkin

1

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Johannes Zuber

object named as

Johannes Zuber

4

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Bruce William Stillman

object named as

Bruce Stillman

7

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author name string

Anthony Mazurek

2

1 reference

25 January 2017

Prem K. Premsrirut

3

1 reference

25 January 2017

Lukas E. Dow

5

1 reference

25 January 2017

Janelle Simon

6

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25 January 2017

Scott W. Lowe

Proceedings of the National Academy of Sciences of the United States of America

8

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25 January 2017

language of work or name

English

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publication date

26 April 2011

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25 January 2017

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25 January 2017

108

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25 January 2017

17

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25 January 2017

7113–7118

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25 January 2017

describes a project that uses

1 reference

Probing tumor phenotypes using stable and regulated synthetic microRNA precursors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3084121

Single copy shRNA configuration for ubiquitous gene knockdown in mice

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3084121

Mammalian Ryk is a Wnt coreceptor required for stimulation of neurite outgrowth

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3084121

Physical and functional interaction between Pes1 and Bop1 in mammalian ribosome biogenesis

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3084121

Acute mutation of retinoblastoma gene function is sufficient for cell cycle re-entry

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3084121

Sensing DNA damage through ATRIP recognition of RPA-ssDNA complexes

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3084121

Pescadillo, a novel cell cycle regulatory protein abnormally expressed in malignant cells

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3084121

Replication protein A: a heterotrimeric, single-stranded DNA-binding protein required for eukaryotic DNA metabolism

19 March 2017

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3084121

19 March 2017

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3084121

Transcriptional activation by tetracyclines in mammalian cells

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3084121

A lentivirus-based system to functionally silence genes in primary mammalian cells, stem cells and transgenic mice by RNA interference

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3084121

A rapid and scalable system for studying gene function in mice using conditional RNA interference

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3084121

Functional identification of optimized RNAi triggers using a massively parallel sensor assay

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3084121

Toolkit for evaluating genes required for proliferation and survival using tetracycline-regulated RNAi

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3084121

Reconstitution of RPA-covered single-stranded DNA-activated ATR-Chk1 signaling

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3084121

Efficient mouse transgenesis using Gateway-compatible ROSA26 locus targeting vectors and F1 hybrid ES cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3084121

Investigation of TRPV1 loss-of-function phenotypes in transgenic shRNA expressing and knockout mice

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3084121

Conditional gene silencing in mammalian cells mediated by a stress-inducible promoter

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3084121

Vagaries of conditional gene targeting

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3084121

Tissue-specific and reversible RNA interference in transgenic mice

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3084121

Reversible gene knockdown in mice using a tight, inducible shRNA expression system

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3084121

Functions of human replication protein A (RPA): from DNA replication to DNA damage and stress responses

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3084121

A lentiviral microRNA-based system for single-copy polymerase II-regulated RNA interference in mammalian cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3084121

Design of a genome-wide siRNA library using an artificial neural network

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3084121

Ectopic expression of Oct-4 blocks progenitor-cell differentiation and causes dysplasia in epithelial tissues

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3084121

Second-generation tetracycline-regulatable promoter: repositioned tet operator elements optimize transactivator synergy while shorter minimal promoter offers tight basal leakiness

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3084121

Self-excising retroviral vectors encoding the Cre recombinase overcome Cre-mediated cellular toxicity

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3084121

Growth inhibition and DNA damage induced by Cre recombinase in mammalian cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3084121

High levels of Cre expression in neuronal progenitors cause defects in brain development leading to microencephaly and hydrocephaly.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3084121

Genetic ablation: targeted expression of a toxin gene causes microphthalmia in transgenic mice.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3084121

Germline transmission of RNAi in mice

20 June 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.1104097108

Efficient method to generate single-copy transgenic mice by site-specific integration in embryonic stem cells

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.1104097108

Methods for studying pro- and antiapoptotic genes in nonimmortal cells

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21482754

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Diphtheria toxin receptor–mediated conditional and targeted cell ablation in transgenic mice

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21482754

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Cell lineage ablation in transgenic mice by cell-specific expression of a toxin gene

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21482754