Activator of G protein signaling 8 (AGS8) is required for hypoxia-induced apoptosis of cardiomyocytes: role of G betagamma and connexin 43 (CX43) (Q28513014)

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English	Activator of G protein signaling 8 (AGS8) is required for hypoxia-induced apoptosis of cardiomyocytes: role of G betagamma and connexin 43 (CX43)	scientific journal article

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scholarly article

2 references

25 January 2017

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19723622%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

Activator of G protein signaling 8 (AGS8) is required for hypoxia-induced apoptosis of cardiomyocytes: role of G betagamma and connexin 43 (CX43) (English)

2 references

25 January 2017

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19723622%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

apoptotic process

0 references

0 references

Gap junction protein, alpha 1

1 reference

GOA release 2020-03-11

Guanine nucleotide binding protein (G protein), beta 1

1 reference

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

Guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1

1 reference

GOA release 2020-03-11

Epidermal growth factor

1 reference

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

Susumu Minamisawa

8

1 reference

Europe PubMed Central

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6 February 2020

Stephen M. Lanier

9

1 reference

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6 February 2020

author name string

Motohiko Sato

1

2 references

25 January 2017

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6 February 2020

Qibin Jiao

2

2 references

25 January 2017

Europe PubMed Central

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6 February 2020

Takashi Honda

3

2 references

25 January 2017

Europe PubMed Central

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6 February 2020

Reiko Kurotani

4

2 references

25 January 2017

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6 February 2020

Eiji Toyota

5

2 references

25 January 2017

Europe PubMed Central

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6 February 2020

Satoshi Okumura

6

2 references

25 January 2017

Europe PubMed Central

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6 February 2020

Tatsuo Takeya

7

2 references

25 January 2017

Europe PubMed Central

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6 February 2020

Yoshihiro Ishikawa

10

2 references

25 January 2017

Europe PubMed Central

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6 February 2020

language of work or name

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publication date

1 September 2009

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6 February 2020

Journal of Biological Chemistry

2 references

25 January 2017

Europe PubMed Central

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6 February 2020

284

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25 January 2017

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6 February 2020

45

2 references

25 January 2017

Europe PubMed Central

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6 February 2020

31431-31440

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6 February 2020

Expansion of signal transduction by G proteins. The second 15 years or so: from 3 to 16 alpha subunits plus betagamma dimers

1 reference

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19 March 2017

Vascular endothelial growth factor is required for coronary collateral growth in the rat

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Accessory proteins for heterotrimeric G-protein: Implication in the cardiovascular system

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29 September 2017

G protein βγ subunits: central mediators of G protein-coupled receptor signaling

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29 September 2017

Activator of G protein signaling 3 null mice: I. Unexpected alterations in metabolic and cardiovascular function

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29 September 2017

Regulation of G protein-coupled receptor signalling: focus on the cardiovascular system and regulator of G protein signalling proteins

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29 September 2017

Phosphorylation at S365 is a gatekeeper event that changes the structure of Cx43 and prevents down-regulation by PKC.

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29 September 2017

Small molecule disruption of G protein beta gamma subunit signaling inhibits neutrophil chemotaxis and inflammation

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29 September 2017

Myocardial reperfusion injury.

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29 September 2017

Programmed death as a therapeutic target to reduce myocardial infarction

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29 September 2017

Preconditioning and postconditioning: united at reperfusion.

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29 September 2017

Opening of connexin 43 hemichannels is increased by lowering intracellular redox potential

1 reference

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29 September 2017

Connexin channel permeability to cytoplasmic molecules

1 reference

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29 September 2017

The modulatory effects of connexin 43 on cell death/survival beyond cell coupling

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2781539

29 September 2017

Change in permeant size selectivity by phosphorylation of connexin 43 gap-junctional hemichannels by PKC.

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29 September 2017

Mechanistic pathways and biological roles for receptor-independent activators of G-protein signaling.

1 reference

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29 September 2017

Structural basis of function in heterotrimeric G proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2781539

29 September 2017

Analysis of Connexin43 phosphorylated at S325, S328 and S330 in normoxic and ischemic heart

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2781539

29 September 2017

Selectivity of connexin 43 channels is regulated through protein kinase C-dependent phosphorylation

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29 September 2017

Non-receptor activators of heterotrimeric G-protein signaling (AGS proteins).

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29 September 2017

Identification of a receptor-independent activator of G protein signaling (AGS8) in ischemic heart and its interaction with Gbetagamma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2781539

29 September 2017

Accessory proteins for G proteins: partners in signaling.

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29 September 2017

Dependence of electrical coupling on mechanical coupling in cardiac myocytes: insights gained from cardiomyopathies caused by defects in cell-cell connections

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29 September 2017

Connexin phosphorylation as a regulatory event linked to gap junction internalization and degradation

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29 September 2017

Epidermal growth factor regulates ubiquitination, internalization and proteasome-dependent degradation of connexin43.

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29 September 2017

Ischemic preconditioning preserves connexin 43 phosphorylation during sustained ischemia in pig hearts in vivo

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29 September 2017

Molecular mechanisms of apoptosis in the cardiac myocyte

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29 September 2017

G protein selectivity is a determinant of RGS2 function.

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RGS4 causes increased mortality and reduced cardiac hypertrophy in response to pressure overload

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29 September 2017

Characterization of a G-protein activator in the neuroblastoma-glioma cell hybrid NG108-15.

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29 September 2017

Leukocyte antigen-related protein tyrosine phosphatase negatively regulates hydrogen peroxide-induced vascular smooth muscle cell apoptosis

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2 June 2018

AGS3 and signal integration by Galpha(s)- and Galpha(i)-coupled receptors: AGS3 blocks the sensitization of adenylyl cyclase following prolonged stimulation of a Galpha(i)-coupled receptor by influencing processing of Galpha(i).

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21 January 2018

Identification and functional analysis of novel phosphorylation sites in Cx43 in rat primary granulosa cells

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21 January 2018

Mitochondrial connexin43 as a new player in the pathophysiology of myocardial ischaemia-reperfusion injury.

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21 January 2018

Impairment of diazoxide-induced formation of reactive oxygen species and loss of cardioprotection in connexin 43 deficient mice

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21 January 2018

High glucose down-regulates intercellular communication in retinal endothelial cells by enhancing degradation of connexin 43 by a proteasome-dependent mechanism

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21 January 2018

Reversible connexin 43 dephosphorylation during hypoxia and reoxygenation is linked to cellular ATP levels

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No ischemic preconditioning in heterozygous connexin43-deficient mice

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Translocation of connexin 43 to the inner mitochondrial membrane of cardiomyocytes through the heat shock protein 90-dependent TOM pathway and its importance for cardioprotection

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12 December 2020

based on heuristic

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Regulation of bcl-2 family proteins during development and in response to oxidative stress in cardiac myocytes: association with changes in mitochondrial membrane potential

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12 December 2020

based on heuristic

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Signaling by a non-dissociated complex of G protein βγ and α subunits stimulated by a receptor-independent activator of G protein signaling, AGS8

1 reference

https://pubmed.ncbi.nlm.nih.gov/19723622

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hemichannels in cardiomyocytes open transiently during ischemia and contribute to reperfusion injury following brief ischemia

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https://pubmed.ncbi.nlm.nih.gov/19723622

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based on heuristic

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Identifiers

10.1074/JBC.M109.014068

2 references

Consolidated OpenCitations Corpus – April 2017

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Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19723622%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

2 references

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19723622%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

2 references

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19723622%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

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