Identification of a novel integrin alpha 6 beta 1 binding site in the angiogenic inducer CCN1 (CYR61) (Q28513880)

Gene Ontology release 2020-05-02

Gene Ontology ID

GO:0071116

Cellular communication network factor 1

1 reference

GOA release 2020-03-11

author name string

Shr-Jeng Leu

1

1 reference

25 January 2017

Ying Liu

2

1 reference

25 January 2017

Ningyu Chen

3

1 reference

25 January 2017

Chih-Chiun Chen

4

1 reference

25 January 2017

Stephen C.-T. Lam

5

1 reference

25 January 2017

Lester F. Lau

Journal of Biological Chemistry

6

1 reference

25 January 2017

language of work or name

English

0 references

publication date

5 September 2003

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25 January 2017

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25 January 2017

278

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25 January 2017

33801–33808

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25 January 2017

36

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25 January 2017

CYR61 (CCN1) is essential for placental development and vascular integrity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305862200

CYR61, a product of a growth factor-inducible immediate early gene, promotes angiogenesis and tumor growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305862200

Breast cancer. Cyr61 is overexpressed, estrogen-inducible, and associated with more advanced disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305862200

Cyr61 promotes breast tumorigenesis and cancer progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305862200

Expression of CYR61, an angiogenic immediate early gene, in arteriosclerosis and its regulation by angiotensin II.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305862200

The angiogenic factor cysteine-rich 61 (CYR61, CCN1) supports vascular smooth muscle cell adhesion and stimulates chemotaxis through integrin alpha(6)beta(1) and cell surface heparan sulfate proteoglycans

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305862200

Identification of integrin alpha(M)beta(2) as an adhesion receptor on peripheral blood monocytes for Cyr61 (CCN1) and connective tissue growth factor (CCN2): immediate-early gene products expressed in atherosclerotic lesions

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305862200

Promoter function and structure of the growth factor-inducible immediate early gene cyr61

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305862200

The angiogenic factor Cyr61 activates a genetic program for wound healing in human skin fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305862200

Cyr61, a product of a growth factor-inducible immediate-early gene, promotes cell proliferation, migration, and adhesion

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305862200

Pro-angiogenic activities of CYR61 (CCN1) mediated through integrins alphavbeta3 and alpha6beta1 in human umbilical vein endothelial cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305862200

Adhesion of human umbilical vein endothelial cells to the immediate-early gene product Cyr61 is mediated through integrin alphavbeta3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305862200

Activation-dependent adhesion of human platelets to Cyr61 and Fisp12/mouse connective tissue growth factor is mediated through integrin alpha(IIb)beta(3)

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305862200

CYR61 stimulates human skin fibroblast migration through Integrin alpha vbeta 5 and enhances mitogenesis through integrin alpha vbeta 3, independent of its carboxyl-terminal domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305862200

Adhesion of human skin fibroblasts to Cyr61 is mediated through integrin alpha 6beta 1 and cell surface heparan sulfate proteoglycans

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305862200

The angiogenic factors Cyr61 and connective tissue growth factor induce adhesive signaling in primary human skin fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305862200

The CCN family of angiogenic regulators: the integrin connection

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305862200

NOV (nephroblastoma overexpressed) and the CCN family of genes: structural and functional issues

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305862200

Proposal for a unified CCN nomenclature

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305862200

Fisp12/mouse connective tissue growth factor mediates endothelial cell adhesion and migration through integrin alphavbeta3, promotes endothelial cell survival, and induces angiogenesis in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305862200

CCN3 (NOV) Is a Novel Angiogenic Regulator of the CCN Protein Family

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305862200

Diversity of function is inherent in matricellular proteins: an appraisal of thrombospondin 1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305862200

Matricellular proteins: extracellular modulators of cell function

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305862200

Human microvascular endothelial cells use beta 1 and beta 3 integrin receptor complexes to attach to laminin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305862200

Human microvascular endothelial cells express integrin-related complexes that mediate adhesion to the extracellular matrix

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305862200

RGD and other recognition sequences for integrins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305862200

Integrin recognition of different cell-binding fragments of laminin (P1, E3, E8) and evidence that alpha 6 beta 1 but not alpha 6 beta 4 functions as a major receptor for fragment E8

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305862200

Two RGD-independent alpha vbeta 3 integrin binding sites on tumstatin regulate distinct anti-tumor properties

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305862200

Multiple beta 1 chain integrins are receptors for invasin, a protein that promotes bacterial penetration into mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305862200

Mouse egg integrin alpha 6 beta 1 functions as a sperm receptor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305862200

Identification of cell binding sites in the laminin alpha 1 chain carboxyl-terminal globular domain by systematic screening of synthetic peptides

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305862200

A mechanism for regulation of melanoma invasion. Ligation of alpha6beta1 integrin by laminin G peptides

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305862200

Identification of a binding site in the disintegrin domain of fertilin required for sperm-egg fusion

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305862200

Novel peptide ligands for integrin alpha 6 beta 1 selected from a phage display library

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305862200

The use of a combinatorial library method to isolate human tumor cell adhesion peptides.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305862200

Stimulation of angiogenesis by Cyr61 gene: a new therapeutic candidate

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305862200

Peptides derived from two separate domains of the matrix protein thrombospondin-1 have anti-angiogenic activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305862200

CD36 mediates the In vitro inhibitory effects of thrombospondin-1 on endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305862200

CD36 associates with CD9 and integrins on human blood platelets.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305862200

The Integrins α3β1and α6β1 Physically and Functionally Associate with CD36 in Human Melanoma Cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305862200