G13 is an essential mediator of platelet activation in hemostasis and thrombosis (Q28513888)

GOA release 2020-03-11

Nina Wettschureck

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Marie-Pierre Gratacap

object named as

Marie-Pierre Gratacap

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Stefan Offermanns

object named as

Stefan Offermanns

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Steffen Massberg

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object named as

Steffen Massberg

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25 January 2017

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Meinrad Gawaz

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25 January 2017

Alexandra Moers

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25 January 2017

Bernhard Nieswandt

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25 January 2017

Sabine Grüner

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25 January 2017

Ildiko Konrad

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25 January 2017

Valerie Schulte

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25 January 2017

Barsom Aktas

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25 January 2017

Melvin I. Simon

Platelets in atherothrombosis

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25 January 2017

language of work or name

English

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publication date

1 November 2003

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25 January 2017

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25 January 2017

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25 January 2017

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1418–1422

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25 January 2017

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7 January 2021

Scientific and therapeutic advances in antiplatelet therapy

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7 January 2021

Defective platelet activation in G alpha(q)-deficient mice.

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7 January 2021

Coactivation of two different G protein-coupled receptors is essential for ADP-induced platelet aggregation

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7 January 2021

Signaling through Gi family members in platelets. Redundancy and specificity in the regulation of adenylyl cyclase and other effectors

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7 January 2021

Activation of G12/G13 results in shape change and Rho/Rho-kinase-mediated myosin light chain phosphorylation in mouse platelets

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7 January 2021

G proteins of the G12 family are activated via thromboxane A2 and thrombin receptors in human platelets

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7 January 2021

Cyclic AMP-dependent phosphorylation of thromboxane A(2) receptor-associated Galpha(13)

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7 January 2021

Vascular system defects and impaired cell chemokinesis as a result of Galpha13 deficiency

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7 January 2021

Interaction of G alpha(12) with G alpha(13) and G alpha(q) signaling pathways

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7 January 2021

Efficient in vivo manipulation of mouse genomic sequences at the zygote stage

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7 January 2021

Inducible gene targeting in mice

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7 January 2021

Costimulation of Gi- and G12/G13-mediated signaling pathways induces integrin alpha IIbbeta 3 activation in platelets

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7 January 2021

Role of thrombin signalling in platelets in haemostasis and thrombosis

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7 January 2021

Mechanisms of platelet aggregation.

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7 January 2021

The role of Rho in G protein-coupled receptor signal transduction

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7 January 2021

Platelet shape change is mediated by both calcium-dependent and -independent signaling pathways. Role of p160 Rho-associated coiled-coil-containing protein kinase in platelet shape change

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7 January 2021

RhoA sustains integrin alpha IIbbeta 3 adhesion contacts under high shear.

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7 January 2021

Impaired activation of murine platelets lacking G alpha(i2)

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7 January 2021

Loss of signaling through the G protein, Gz, results in abnormal platelet activation and altered responses to psychoactive drugs

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7 January 2021

Coordinated signaling through both G12/13 and G(i) pathways is sufficient to activate GPIIb/IIIa in human platelets

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7 January 2021

Characterization of the expression of PDZ-RhoGEF, LARG and G(alpha)12/G(alpha)13 proteins in the murine nervous system.

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7 January 2021

Determination of GTP loading on Rho

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7 January 2021

Complementary roles of glycoprotein VI and alpha2beta1 integrin in collagen-induced thrombus formation in flowing whole blood ex vivo

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7 January 2021

A crucial role of glycoprotein VI for platelet recruitment to the injured arterial wall in vivo

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7 January 2021