Exploring the mode of action of bioactive compounds by microfluidic transcriptional profiling in mycobacteria (Q28535015)

8

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Martin L. Hibberd

object named as

Martin L Hibberd

9

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author name string

Paul Murima

1

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Paola Florez de Sessions

2

0 references

Vivian Lim

3

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Ahmad Nazri Mohamed Naim

4

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Helena I M Boshoff

6

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Vasan K Sambandamurthy

7

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Mark Schreiber

10

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Srinivasa P S Rao

Creative Commons CC0 License

11

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language of work or name

English

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publication date

2013

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published in

PLOS One

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volume

8

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issue

7

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page(s)

e69191

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copyright license

start time

31 July 2013

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted, dedicated to the public domain by copyright holder

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describes a project that uses

1 reference

Spiroindolones, a potent compound class for the treatment of malaria

1 reference

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Type IIA topoisomerase inhibition by a new class of antibacterial agents

19 March 2017

1 reference

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Benzothiazinones kill Mycobacterium tuberculosis by blocking arabinan synthesis

19 March 2017

1 reference

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A common mechanism of cellular death induced by bactericidal antibiotics

19 March 2017

1 reference

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Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence

19 March 2017

1 reference

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Drugs for bad bugs: confronting the challenges of antibacterial discovery

19 March 2017

1 reference

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A diarylquinoline drug active on the ATP synthase of Mycobacterium tuberculosis

7 April 2017

1 reference

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RNA signatures allow rapid identification of pathogens and antibiotic susceptibilities

7 April 2017

1 reference

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Cyclopropyl carboxamides, a chemically novel class of antimalarial agents identified in a phenotypic screen

29 September 2017

1 reference

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Anti-infectives: can cellular screening deliver?

29 September 2017

1 reference

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A chemical genetic screen in Mycobacterium tuberculosis identifies carbon-source-dependent growth inhibitors devoid of in vivo efficacy

29 September 2017

1 reference

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Lipiarmycin targets RNA polymerase and has good activity against multidrug-resistant strains of Mycobacterium tuberculosis

29 September 2017

1 reference

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In silico activity profiling reveals the mechanism of action of antimalarials discovered in a high-throughput screen

29 September 2017

1 reference

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High throughput gene expression measurement with real time PCR in a microfluidic dynamic array

29 September 2017

1 reference

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Target deconvolution strategies in drug discovery

29 September 2017

1 reference

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Microfluidic large-scale integration: the evolution of design rules for biological automation

29 September 2017

1 reference

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Antibacterial drug discovery--then, now and the genomics future

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3729944

The PIN-domain toxin-antitoxin array in mycobacteria

29 September 2017

1 reference

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Can cell systems biology rescue drug discovery?

29 September 2017

1 reference

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Target-based drug discovery: is something wrong?

29 September 2017

1 reference

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Prediction of mechanisms of action of antibacterial compounds by gene expression profiling.

29 September 2017

1 reference

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Novel antibacterials: a genomics approach to drug discovery

29 September 2017

1 reference

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Delivering novel targets and antibiotics from genomics

29 September 2017

1 reference

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An effective method of RNA extraction from bacteria refractory to disruption, including mycobacteria.

29 September 2017

1 reference

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How antibacterials really work: impact on drug discovery.

29 September 2017

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0069191

The transcriptional responses of Mycobacterium tuberculosis to inhibitors of metabolism: novel insights into drug mechanisms of action

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0069191

The natural product cyclomarin kills Mycobacterium tuberculosis by targeting the ClpC1 subunit of the caseinolytic protease

21 January 2018

1 reference

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Exploring the Mode-of-Action of Bioactive Compounds by Chemical-Genetic Profiling in Yeast

21 January 2018

1 reference

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Microarrays and molecular research: noise discovery?

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23935951

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Prediction of cancer outcome with microarrays: a multiple random validation strategy

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23935951

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

1 reference

https://pubmed.ncbi.nlm.nih.gov/23935951

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1371/JOURNAL.PONE.0069191

1 reference

ADS bibcode

2013PLoSO...869191M

0 references

1 reference

1 reference

PubMed publication ID

23935951

1 reference