Discovery of triterpenoids as reversible inhibitors of α/β-hydrolase domain containing 12 (ABHD12) (Q28539329)

2

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Jarmo T Laitinen

object named as

Jarmo T Laitinen

12

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author name string

Teija Parkkari

1

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Tuomo Laitinen

3

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Dina Navia-Paldanius

4

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Roosa Rytilahti

5

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Miia Vaara

6

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Marko Lehtonen

7

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Sami Alakurtti

8

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Tapio Nevalainen

10

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Juha R Savinainen

Creative Commons Attribution 4.0 International

11

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language of work or name

English

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publication date

2014

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published in

PLOS One

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volume

9

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issue

5

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page(s)

e98286

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copyright license

start time

30 May 2014

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

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describes a project that uses

ImageJ

1 reference

Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4045134/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

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ABHD12 controls brain lysophosphatidylserine pathways that are deregulated in a murine model of the neurodegenerative disease PHARC

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Biochemical and pharmacological characterization of human α/β-hydrolase domain containing 6 (ABHD6) and 12 (ABHD12)

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The antinociceptive triterpene β-amyrin inhibits 2-arachidonoylglycerol (2-AG) hydrolysis without directly targeting cannabinoid receptors

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Activation of cannabinoid receptors by the pentacyclic triterpene α,β-amyrin inhibits inflammatory and neuropathic persistent pain in mice.

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Mutations in ABHD12 cause the neurodegenerative disease PHARC: An inborn error of endocannabinoid metabolism

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Synthesis and structure-activity relationship study of novel cytotoxic carbamate and N-acylheterocyclic bearing derivatives of betulin and betulinic acid.

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