Machine Learning Models and Pathway Genome Data Base for Trypanosoma cruzi Drug Discovery (Q28545842)

12

object named as

James H McKerrow

0 references

author name string

Jair Lage de Siqueira-Neto

2

0 references

Laura-Isobel McCall

3

0 references

Malabika Sarker

4

0 references

Maneesh Yadav

5

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Elizabeth L Ponder

6

0 references

E Adam Kallel

7

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Danielle Kellar

8

0 references

Steven Chen

9

0 references

Michelle Arkin

10

0 references

Barry A Bunin

11

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Carolyn Talcott

PLoS Neglected Tropical Diseases

13

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language of work or name

English

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publication date

2015

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published in

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volume

9

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issue

6

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page(s)

e0003878

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copyright license

Creative Commons Attribution 4.0 International

start time

26 June 2015

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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Diverse inhibitor chemotypes targeting Trypanosoma cruzi CYP51

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Chagas disease: "the new HIV/AIDS of the Americas"

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Identification of three classes of heteroaromatic compounds with activity against intracellular Trypanosoma cruzi by chemical library screening

19 March 2017

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Analysis of pharmacology data and the prediction of adverse drug reactions and off-target effects from chemical structure

19 March 2017

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19 March 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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Identification of small-molecule inhibitors of Trypansoma cruzi replication

29 September 2017

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29 September 2017

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29 September 2017

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Analysis and hit filtering of a very large library of compounds screened against Mycobacterium tuberculosis

29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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Targeting the polyamine biosynthetic enzymes: a promising approach to therapy of African sleeping sickness, Chagas' disease, and leishmaniasis

29 September 2017

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Computational approaches that predict metabolic intermediate complex formation with CYP3A4 (+b5).

29 September 2017

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Cheminformatics analysis and learning in a data pipelining environment

29 September 2017

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Improved naïve Bayesian modeling of numerical data for absorption, distribution, metabolism and excretion (ADME) property prediction

29 September 2017

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The Pathway Tools cellular overview diagram and Omics Viewer

29 September 2017

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Pyronaridine, a novel modulator of P-glycoprotein-mediated multidrug resistance in tumor cells in vitro and in vivo

29 September 2017

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Studies on a new antimalarial compound: pyronaridine

29 September 2017

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Trypanosoma cruzi Clone Dm28c Draft Genome Sequence

29 September 2017

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Human and rat liver phenol sulfotransferase: structure-activity relationships for phenolic substrates.

3 June 2018

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The discovery of first-in-class drugs: origins and evolution.

3 June 2018

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Computational models for neglected diseases: gaps and opportunities

21 January 2018

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Chagas disease: a new worldwide challenge.

21 January 2018

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Chagas disease: pushing through the pipeline

21 January 2018

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Safety of benznidazole use in the treatment of chronic Chagas' disease.

21 January 2018

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Computational discovery of novel trypanosomicidal drug-like chemicals by using bond-based non-stochastic and stochastic quadratic maps and linear discriminant analysis

21 January 2018

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The MetaCyc database of metabolic pathways and enzymes and the BioCyc collection of Pathway/Genome Databases.

21 January 2018

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Using extended-connectivity fingerprints with Laplacian-modified Bayesian analysis in high-throughput screening follow-up

21 January 2018

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Cardioprotective effects of verapamil on myocardial structure and function in a murine model of chronic Trypanosoma cruzi infection (Brazil Strain): an echocardiographic study

21 January 2018

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Effects of early and late verapamil administration on the development of cardiomyopathy in experimental chronic Trypanosoma cruzi (Brazil strain) infection

21 January 2018

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The activity against Trypanosoma cruzi and cutaneous leishmaniasis, and toxicity, of moxipraquine (349C59).

21 January 2018

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New ligand-based approach for the discovery of antitrypanosomal compounds

21 January 2018

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A novel non-stochastic quadratic fingerprints-based approach for the ‘in silico’ discovery of new antitrypanosomal compounds

21 January 2018

1 reference

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An Estimate of the Burden of Chagas Disease in the United States

21 January 2018

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Posaconazole versus benznidazole for chronic Chagas' disease

21 January 2018

1 reference

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The bisbenzylisoquinoline alkaloids, tetrandine and fangchinoline, enhance the cytotoxicity of multidrug resistance-related drugs via modulation of P-glycoprotein.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4482694

Effects of verapamil on acute murine Chagas' disease

27 November 2018

1 reference

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A modified bismuth-containing quadruple therapy including a short course of furazolidone for Helicobacter pylori eradication after sequential therapy failure

27 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26114876

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Crystal structure of the Trypanosoma cruzi trypanothione reductase.mepacrine complex

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26114876

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1371/JOURNAL.PNTD.0003878

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

1310655

OpenCitations bibliographic resource ID

1310655

1 reference