Circulating Autoantibodies in Age-Related Macular Degeneration Recognize Human Macular Tissue Antigens Implicated in Autophagy, Immunomodulation, and Protection from Oxidative Stress and Apoptosis (Q28551885)

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English	Circulating Autoantibodies in Age-Related Macular Degeneration Recognize Human Macular Tissue Antigens Implicated in Autophagy, Immunomodulation, and Protection from Oxidative Stress and Apoptosis	scientific article

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scholarly article

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Circulating Autoantibodies in Age-Related Macular Degeneration Recognize Human Macular Tissue Antigens Implicated in Autophagy, Immunomodulation, and Protection from Oxidative Stress and Apoptosis (English)

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based on heuristic

inferred from title

macular degeneration

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based on heuristic

inferred from title

Deirdre Hollingsworth

4

object named as

T J Hollingsworth

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object named as

Marko Z Radic

20

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Alessandro Iannaccone

object named as

Alessandro Iannaccone

1

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Stephen B Kritchevsky

17

object named as

Stephen B Kritchevsky

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Suzanne Satterfield

11

object named as

Suzanne Satterfield

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Tamara B. Harris

14

object named as

Tamara Harris

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Barbara Jean Jennings

9

object named as

Barbara J Jennings

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Allison Umfress

5

object named as

Allison Umfress

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author name string

Francesco Giorgianni

2

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David D New

3

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Albert H Alhatem

6

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Indira Neeli

7

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Nataliya I Lenchik

8

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Jorge I Calzada

10

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Dennis Mathews

12

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Rocio I Diaz

13

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Karen C Johnson

15

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Steve Charles

16

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Ivan C Gerling

18

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Sarka Beranova-Giorgianni

19

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language of work or name

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publication date

2015

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10

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12

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e0145323

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copyright license

Creative Commons Attribution 4.0 International

30 December 2015

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April 2022 Public Data File from Crossref

copyright status

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NLRP3 Inflammasome and Pathobiology in AMD

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Autophagy and heterophagy dysregulation leads to retinal pigment epithelium dysfunction and development of age-related macular degeneration

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Genetics of immunological and inflammatory components in age-related macular degeneration

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Using genetic variation and environmental risk factor data to identify individuals at high risk for age-related macular degeneration

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An imbalance of human complement regulatory proteins CFHR1, CFHR3 and factor H influences risk for age-related macular degeneration (AMD)

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alpha-Crystallin distribution in retinal pigment epithelium and effect of gene knockouts on sensitivity to oxidative stress

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A common CFH haplotype, with deletion of CFHR1 and CFHR3, is associated with lower risk of age-related macular degeneration

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CFH haplotypes without the Y402H coding variant show strong association with susceptibility to age-related macular degeneration

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A randomized, placebo-controlled, clinical trial of high-dose supplementation with vitamins C and E, beta carotene, and zinc for age-related macular degeneration and vision loss: AREDS report no. 8

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An integrated hypothesis that considers drusen as biomarkers of immune-mediated processes at the RPE-Bruch's membrane interface in aging and age-related macular degeneration

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Deletion of autophagy inducer RB1CC1 results in degeneration of the retinal pigment epithelium

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Alpha crystallins in the retinal pigment epithelium and implications for the pathogenesis and treatment of age-related macular degeneration

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Genetic testing for age-related macular degeneration: not indicated now.

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Prevalence of anti-retinal autoantibodies in different stages of Age-related macular degeneration

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C3 R102G polymorphism increases risk of age-related macular degeneration

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Immunopathological aspects of age-related macular degeneration

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29 September 2017

Oxidative damage-induced inflammation initiates age-related macular degeneration.

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Age-related macular degeneration and the immune response: implications for therapy

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New therapeutic targets in atrophic age-related macular degeneration

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Macular pigment optical density in the elderly: findings in a large biracial Midsouth population sample

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Transformation of the proteasome with age-related macular degeneration

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Changes in select redox proteins of the retinal pigment epithelium in age-related macular degeneration

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Age-related decline in VIP-positive parasympathetic nerve fibers in the human submacular choroid

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4696815

29 September 2017

The role of anti-alpha-enolase autoantibodies in pathogenicity of autoimmune-mediated retinopathy.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4696815

29 September 2017

Age-related macular degeneration--emerging pathogenetic and therapeutic concepts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4696815

29 September 2017

Carboxyethylpyrrole oxidative protein modifications stimulate neovascularization: Implications for age-related macular degeneration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4696815

29 September 2017

Common variation in three genes, including a noncoding variant in CFH, strongly influences risk of age-related macular degeneration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4696815

29 September 2017

Variation in factor B (BF) and complement component 2 (C2) genes is associated with age-related macular degeneration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4696815

29 September 2017

The role of inflammation in the pathogenesis of age-related macular degeneration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4696815

29 September 2017

Annexin A5 in cardiovascular disease and systemic lupus erythematosus.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4696815

29 September 2017

A simplified severity scale for age-related macular degeneration: AREDS Report No. 18

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4696815

29 September 2017

The Age-Related Eye Disease Study severity scale for age-related macular degeneration: AREDS Report No. 17

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4696815

29 September 2017

Inflammation, the complement system and the diseases of aging

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4696815

29 September 2017

Evidence for an inflammatory process in age-related macular degeneration gains new support

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4696815

29 September 2017

Inflammation and the degenerative diseases of aging

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4696815

29 September 2017

Proteomic approaches to understanding age-related macular degeneration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4696815

29 September 2017

Complex autoantibody repertoires in patients with glaucoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4696815

29 September 2017

Innate Immunity, Local Inflammation, and Degenerative Disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4696815

29 September 2017

Autoantibody-induced apoptosis as a possible mechanism of autoimmune retinopathy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4696815

29 September 2017

Drusen proteome analysis: an approach to the etiology of age-related macular degeneration.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4696815

29 September 2017

A role for local inflammation in the formation of drusen in the aging eye.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4696815

29 September 2017

The Alzheimer's A beta -peptide is deposited at sites of complement activation in pathologic deposits associated with aging and age-related macular degeneration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4696815

29 September 2017

Immunological and aetiological aspects of macular degeneration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4696815

29 September 2017

Heat shock cognate-70 gene expression declines during normal aging of the primate retina.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4696815

29 September 2017

Drusen associated with aging and age-related macular degeneration contain proteins common to extracellular deposits associated with atherosclerosis, elastosis, amyloidosis, and dense deposit disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4696815

29 September 2017

Molecular composition of drusen as related to substructural phenotype

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4696815

29 September 2017

Epidemiology of age-related macular degeneration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4696815

29 September 2017

Senile macular degeneration. The involvement of giant cells in atrophy of the retinal pigment epithelium

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4696815

29 September 2017

Immunohistochemical localization of heat shock protein-70 in normal-appearing and atherosclerotic specimens of human arteries.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4696815

29 September 2017

Heat shock prevents lipopolysaccharide-induced tumor necrosis factor-alpha synthesis by rat mononuclear phagocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4696815

29 September 2017

Association of Smoking and CFH and ARMS2 Risk Variants With Younger Age at Onset of Neovascular Age-Related Macular Degeneration.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4696815

3 June 2018

Induction of nuclear factor-κB responses by the S100A9 protein is Toll-like receptor-4-dependent

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4696815

3 June 2018

The anti-inflammatory mechanisms of Hsp70

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4696815

3 June 2018

Anti-enolase-alpha autoantibodies in cancer-associated retinopathy: epitope mapping and cytotoxicity on retinal cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4696815

3 June 2018

Antibodies to recoverin induce apoptosis of photoreceptor and bipolar cells in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4696815

3 June 2018

Reticular pseudodrusen are subretinal drusenoid deposits

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0145323

21 January 2018

The Age-Related Eye Disease Study system for classifying age-related macular degeneration from stereoscopic color fundus photographs: the Age-Related Eye Disease Study Report Number 6.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0145323

21 January 2018

Complement factor H variant Y402H is a major risk determinant for geographic atrophy and choroidal neovascularization in smokers and nonsmokers.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0145323

21 January 2018

Proteomic and genomic biomarkers for age-related macular degeneration.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0145323

21 January 2018

Reliability assessment of a rod photoreceptor outer segment grading system

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0145323

21 January 2018

Age-related macular degeneration: ultrastructural studies of the relationship of leucocytes to angiogenesis

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0145323

21 January 2018

Carboxyethylpyrrole protein adducts and autoantibodies, biomarkers for age-related macular degeneration.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0145323

21 January 2018

Retinal autoantibody profile in early age-related macular degeneration: preliminary findings from the Blue Mountains Eye Study

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0145323

21 January 2018

Identification of anti-retinal antibodies in patients with age-related macular degeneration.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0145323

21 January 2018

Identification of plasma membrane autoantigens in autoimmune hepatitis type 1 using a proteomics tool.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0145323

21 January 2018

CHIP promotes proteasomal degradation of familial ALS-linked mutant SOD1 by ubiquitinating Hsp/Hsc70.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0145323

21 January 2018

Annexin A5 stimulates autophagy and inhibits endocytosis

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0145323

21 January 2018

Mechanism of CAR syndrome: anti-recoverin antibodies are the inducers of retinal cell apoptotic death via the caspase 9- and caspase 3-dependent pathway

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0145323

21 January 2018

Cellular targets of anti-alpha-enolase autoantibodies of patients with autoimmune retinopathy

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0145323

21 January 2018

S100 alone has the same destructive effect on retinal ganglion cells as in combination with HSP 27 in an autoimmune glaucoma model.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0145323

21 January 2018

Molecular composition of drusen and possible involvement of anti-retinal autoimmunity in two different forms of macular degeneration in cynomolgus monkey (Macaca fascicularis).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4696815

27 November 2018

LC-MS/MS analysis of peptides with methanol as organic modifier: improved limits of detection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4696815

27 November 2018

Inflammation and age-related macular degeneration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4696815

27 November 2018

Proteasome function and protein oxidation in the aged retina

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4696815

27 November 2018

Cancer-associated retinopathy induced by both anti-recoverin and anti-hsc70 antibodies in vivo.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4696815

27 November 2018

Apoptotic retinal cell death induced by antirecoverin autoantibodies of cancer-associated retinopathy.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4696815

27 November 2018

Annexins in Bruch's membrane and drusen

1 reference

https://pubmed.ncbi.nlm.nih.gov/26717306

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Annexin V expression and anti-annexin V antibodies in type 1 diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/26717306

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Damage-associated molecular pattern S100A9 increases bactericidal activity of human neutrophils by enhancing phagocytosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/26717306

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Complement factor H increases risk for atrophic age-related macular degeneration

1 reference

https://pubmed.ncbi.nlm.nih.gov/26717306

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genetics. A clearer view of macular degeneration

1 reference

https://pubmed.ncbi.nlm.nih.gov/26717306

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Deletion of CFHR3 and CFHR1 genes in age-related macular degeneration

1 reference

https://pubmed.ncbi.nlm.nih.gov/26717306

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dynamic mobility of immunological cells expressing S100A8 and S100A9 in vivo: a variety of functional roles of the two proteins as regulators in acute inflammatory reaction

1 reference

https://pubmed.ncbi.nlm.nih.gov/26717306

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Serum autoantibody biomarkers for age-related macular degeneration and possible regulators of neovascularization

1 reference

https://pubmed.ncbi.nlm.nih.gov/26717306

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antibodies to alpha B-crystallin, vimentin, and heat shock protein 70 in aqueous humor of patients with normal tension glaucoma and IgG antibody patterns against retinal antigen in aqueous humor

1 reference

https://pubmed.ncbi.nlm.nih.gov/26717306

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Autoantibodies to retinal astrocytes associated with age-related macular degeneration

1 reference

https://pubmed.ncbi.nlm.nih.gov/26717306

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An ultrastructural study of the role of leucocytes and fibroblasts in the breakdown of Bruch's membrane

1 reference

https://pubmed.ncbi.nlm.nih.gov/26717306

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Senile macular degeneration: the involvement of immunocompetent cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/26717306

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CFH gene variant, Y402H, and smoking, body mass index, environmental associations with advanced age-related macular degeneration

1 reference

https://pubmed.ncbi.nlm.nih.gov/26717306

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Crystallin distribution in Bruch's membrane-choroid complex from AMD and age-matched donor eyes

1 reference

https://pubmed.ncbi.nlm.nih.gov/26717306

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1371/JOURNAL.PONE.0145323

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2015PLoSO..1045323I

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PMC publication ID

0 references

PubMed publication ID

0 references

ResearchGate publication ID

0 references

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