Polypyrimidine tract-binding protein promotes insulin secretory granule biogenesis (Q28567445)

Gene Ontology release 2020-05-02

Gene Ontology ID

GO:1904409

positive regulation of secretory granule organization

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Gene Ontology release 2020-05-02

Gene Ontology ID

GO:1904411

negative regulation of secretory granule organization

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Gene Ontology release 2020-05-02

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4

Hans-Detlev Saeger

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Paul Verkade

6

object named as

Paul Verkade

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31 January 2017

Klaus-Peter Knoch

1

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31 January 2017

Hendrik Bergert

2

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31 January 2017

Barbara Borgonovo

3

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31 January 2017

Anke Altkrüger

5

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31 January 2017

Michele Solimena

Regulation of the biosynthesis of insulin-secretory-granule proteins. Co-ordinate translational control is exerted on some, but not all, granule matrix constituents

7

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31 January 2017

1 March 2004

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31 January 2017

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31 January 2017

6

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31 January 2017

3

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31 January 2017

207–214

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31 January 2017

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Regulation by glucose of the biosynthesis of PC2, PC3 and proinsulin in (ob/ob) mouse islets of Langerhans

21 January 2018

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Translational control of insulin biosynthesis. Evidence for regulation of elongation, initiation and signal-recognition-particle-mediated translational arrest by glucose.

21 January 2018

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Control of insulin mRNA stability in rat pancreatic islets. Regulatory role of a 3'-untranslated region pyrimidine-rich sequence

21 January 2018

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Post-transcriptional regulation: the dawn of PTB.

21 January 2018

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A cytoplasmic 57-kDa protein that is required for translation of picornavirus RNA by internal ribosomal entry is identical to the nuclear pyrimidine tract-binding protein

21 January 2018

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A Xenopus protein related to hnRNP I has a role in cytoplasmic RNA localization.

21 January 2018

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The upstream sequence element of the C2 complement poly(A) signal activates mRNA 3' end formation by two distinct mechanisms.

21 January 2018

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Delineation of a novel pathway that regulates CD154 (CD40 ligand) expression

21 January 2018

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Characterization of cDNAs encoding the polypyrimidine tract-binding protein

21 January 2018

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hnRNP 1, the polyprimidine tract-binding protein: distinct nuclear localization and association with hnRNAs

21 January 2018

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Dephosphorylation of beta2-syntrophin and Ca2+/mu-calpain-mediated cleavage of ICA512 upon stimulation of insulin secretion

21 January 2018

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Stabilization of the receptor protein tyrosine phosphatase-like protein ICA512 in GH4C1 cells upon treatment with estradiol, insulin, and epidermal growth factor

21 January 2018

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Transient expression of cellular polypyrimidine-tract binding protein stimulates cap-independent translation directed by both picornaviral and flaviviral internal ribosome entry sites In vivo

21 January 2018

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Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells

21 January 2018

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Glucagon-like peptide I stimulates insulin gene expression and increases cyclic AMP levels in a rat islet cell line

21 January 2018

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Protein kinase A phosphorylation modulates transport of the polypyrimidine tract-binding protein

21 January 2018

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Insulin mediates glucose-stimulated phosphorylation of PHAS-I by pancreatic beta cells. An insulin-receptor mechanism for autoregulation of protein synthesis by translation

21 January 2018

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Chromogranin A, an "on/off" switch controlling dense-core secretory granule biogenesis

21 January 2018

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Secretory granule biogenesis and chromogranin A: master gene, on/off switch or assembly factor?

21 January 2018

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Dense-core granules: a specific hallmark of the neuronal/neurosecretory cell phenotype

21 January 2018

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Establishment of 2-mercaptoethanol-dependent differentiated insulin-secreting cell lines

21 January 2018

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Cell type-dependent variations in the subcellular distribution of alpha-mannosidase I and II

21 January 2018

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An mRNA stability complex functions with poly(A)-binding protein to stabilize mRNA in vitro

21 January 2018

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Effect of proinflammatory cytokines on gene expression of the diabetes-associated autoantigen IA-2 in INS-1 cells

21 January 2018

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Translational control of proinsulin synthesis by glucose

21 January 2018

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Neurosecretion Competence, an Independently Regulated Trait of the Neurosecretory Cell Phenotype

21 January 2018

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Effects of glucose on proinsulin messenger RNA in rats in vivo

21 January 2018

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7 January 2021

Hypoxia may increase rat insulin mRNA levels by promoting binding of the polypyrimidine tract-binding protein (PTB) to the pyrimidine-rich insulin mRNA 3'-untranslated region.

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7 January 2021

Identification and purification of a 62,000-dalton protein that binds specifically to the polypyrimidine tract of introns

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7 January 2021

ICA 512, an autoantigen of type I diabetes, is an intrinsic membrane protein of neurosecretory granules

1 reference

7 January 2021

Evidence that glucose "marks" beta cells resulting in preferential release of newly synthesized insulin

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7 January 2021

Differential Rates of Release of Newly Synthesized and of Stored Insulin from Pancreatic Islets*

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7 January 2021

An improved method for isolation of mouse pancreatic islets

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7 January 2021

Identifiers

DOI

10.1038/NCB1099

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Consolidated OpenCitations Corpus – April 2017

Dimensions Publication ID

3437979

1029111313

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3437979

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Consolidated OpenCitations Corpus – April 2017

Consolidated OpenCitations Corpus – April 2017

1 reference