Targeting caspase-1 by inhalation-therapy: effects of Ac-YVAD-CHO on IL-1 beta, IL-18 and downstream proinflammatory parameters as detected in rat endotoxaemia (Q28567849)

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English	Targeting caspase-1 by inhalation-therapy: effects of Ac-YVAD-CHO on IL-1 beta, IL-18 and downstream proinflammatory parameters as detected in rat endotoxaemia	scientific journal article

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scholarly article

1 reference

PubMed publication ID

31 January 2017

Targeting caspase-1 by inhalation-therapy: effects of Ac-YVAD-CHO on IL-1 beta, IL-18 and downstream proinflammatory parameters as detected in rat endotoxaemia (English)

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PubMed publication ID

31 January 2017

Josef Pfeilschifter

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object named as

Josef Pfeilschifter

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31 January 2017

author name string

Kim A. Boost

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31 January 2017

Sandra Hoegl

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31 January 2017

Christian Hofstetter

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31 January 2017

Michael Flondor

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31 January 2017

Klaus Stegewerth

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31 January 2017

Ilka Platacis

6

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31 January 2017

Heiko Muhl

8

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31 January 2017

Bernhard Zwissler

9

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31 January 2017

publication date

1 May 2007

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31 January 2017

Intensive Care Medicine

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PubMed publication ID

31 January 2017

33

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31 January 2017

5

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31 January 2017

863–871

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31 January 2017

Therapeutic application of caspase 1/interleukin-1beta-converting enzyme inhibitor decreases the death rate in severe acute experimental pancreatitis

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https://pubmed.ncbi.nlm.nih.gov/17384935

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Lipopolysaccharide activates caspase-1 (interleukin-1-converting enzyme) in cultured monocytic and endothelial cells.

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https://pubmed.ncbi.nlm.nih.gov/17384935

12 December 2020

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Year in review in intensive care medicine, 2004. I. Respiratory failure, infection, and sepsis

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https://pubmed.ncbi.nlm.nih.gov/17384935

12 December 2020

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Role of the neutrophil in septic shock and the adult respiratory distress syndrome

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https://pubmed.ncbi.nlm.nih.gov/17384935

12 December 2020

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Interleukin-18 promotes joint inflammation and induces interleukin-1-driven cartilage destruction

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https://pubmed.ncbi.nlm.nih.gov/17384935

12 December 2020

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Role of inflammatory mediators in the pathophysiology of acute respiratory distress syndrome

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https://pubmed.ncbi.nlm.nih.gov/17384935

12 December 2020

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Mice deficient in IL-1 beta-converting enzyme are defective in production of mature IL-1 beta and resistant to endotoxic shock

1 reference

https://pubmed.ncbi.nlm.nih.gov/17384935

12 December 2020

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Interleukin-18 and interleukin-1 beta: two cytokine substrates for ICE (caspase-1).

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https://pubmed.ncbi.nlm.nih.gov/17384935

12 December 2020

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Interleukin-18 (IFNgamma-inducing factor) induces IL-8 and IL-1beta via TNFalpha production from non-CD14+ human blood mononuclear cells

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https://pubmed.ncbi.nlm.nih.gov/17384935

12 December 2020

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Interleukin-1beta

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https://pubmed.ncbi.nlm.nih.gov/17384935

12 December 2020

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Systemic delivery of drugs to humans via inhalation

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Transcriptional mechanisms of acute lung injury

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Attenuation of increased myocardial ischaemia-reperfusion injury conferred by hypercholesterolaemia through pharmacological inhibition of the caspase-1 cascade

1 reference

https://pubmed.ncbi.nlm.nih.gov/17384935

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The systemic inflammatory response syndrome

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https://pubmed.ncbi.nlm.nih.gov/17384935

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The lungs as a portal of entry for systemic drug delivery

1 reference

https://pubmed.ncbi.nlm.nih.gov/17384935

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Caspase-1-inhibitor ac-YVAD-cmk reduces LPS-lethality in rats without affecting haematology or cytokine responses

1 reference

https://pubmed.ncbi.nlm.nih.gov/17384935

12 December 2020

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Interleukin-10 aerosol reduces proinflammatory mediators in bronchoalveolar fluid of endotoxemic rat.

1 reference

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Proinflammatory activity in bronchoalveolar lavage fluids from patients with ARDS, a prominent role for interleukin-1

1 reference

https://pubmed.ncbi.nlm.nih.gov/17384935

12 December 2020

based on heuristic

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Year in review in intensive care medicine. 2005. I. Acute respiratory failure and acute lung injury, ventilation, hemodynamics, education, renal failure

1 reference

https://pubmed.ncbi.nlm.nih.gov/17384935

12 December 2020

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The predictive role of serum and bronchoalveolar lavage cytokines and adhesion molecules for acute respiratory distress syndrome development and outcome

1 reference

https://pubmed.ncbi.nlm.nih.gov/17384935

12 December 2020

based on heuristic

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The acute respiratory distress syndrome

1 reference

https://pubmed.ncbi.nlm.nih.gov/17384935

12 December 2020

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Inflammatory cytokines in patients with persistence of the acute respiratory distress syndrome

1 reference

https://pubmed.ncbi.nlm.nih.gov/17384935

12 December 2020

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Biologic basis for interleukin-1 in disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/17384935

12 December 2020

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Inhibition of caspase-3-like activity prevents apoptosis while retaining functionality of human chondrocytes in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/17384935

12 December 2020

based on heuristic

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Altered cytokine export and apoptosis in mice deficient in interleukin-1 beta converting enzyme

1 reference

https://pubmed.ncbi.nlm.nih.gov/17384935

12 December 2020

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Cyclosporin derivatives inhibit interleukin 1 beta induction of nitric oxide synthase in renal mesangial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/17384935

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IFN-gamma production by antigen-presenting cells: mechanisms emerge.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17384935

12 December 2020

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Interleukin-18 bioactivity: a novel target for immunopharmacological anti-inflammatory intervention

1 reference

https://pubmed.ncbi.nlm.nih.gov/17384935

12 December 2020

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Immunoreactive interleukin-1 in bronchoalveolar lavage fluid of high-risk patients and patients with the adult respiratory distress syndrome

1 reference

https://pubmed.ncbi.nlm.nih.gov/17384935

12 December 2020

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Cytokines, sepsis and immunomodulation

1 reference

https://pubmed.ncbi.nlm.nih.gov/17384935

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Aerosol delivery during mechanical ventilation to the rat.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17384935

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The roles of IFN gamma in protection against tumor development and cancer immunoediting

1 reference

https://pubmed.ncbi.nlm.nih.gov/17384935

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Dexamethasone differentially affects interleukin 1 beta- and cyclic AMP-induced nitric oxide synthase mRNA expression in renal mesangial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/17384935

12 December 2020

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Caspase-1 processes IFN-gamma-inducing factor and regulates LPS-induced IFN-gamma production

1 reference

https://pubmed.ncbi.nlm.nih.gov/17384935

12 December 2020

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A Synthetic Inhibitor of Interleukin-lβ Converting Enzyme Prevents Endotoxin-Induced Interleukin-lβ ProductionIn VitroandIn Vivo

1 reference

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Selective pulmonary vasodilation in acute respiratory distress syndrome

1 reference

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The alveolar space is the site of intense inflammatory and profibrotic reactions in the early phase of acute respiratory distress syndrome

1 reference

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Purification of a factor which provides a costimulatory signal for gamma interferon production

1 reference

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Current concepts of the inflammatory response after major trauma: an update

1 reference

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Identifiers

10.1007/S00134-007-0588-0

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

PubMed publication ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

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