Cell junction-associated proteins IQGAP1, MAGI-2, CASK, spectrins, and alpha-actinin are components of the nephrin multiprotein complex (Q28570208)

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13 January 2020

title

Cell junction-associated proteins IQGAP1, MAGI-2, CASK, spectrins, and alpha-actinin are components of the nephrin multiprotein complex (English)

2 references

31 January 2017

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13 January 2020

1 reference

Gene Ontology release 2020-05-02

1

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13 January 2020

Jennifer J Ryan

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13 January 2020

Huilin Zhou

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author name string

Krystyna Kudlicka

3

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13 January 2020

Noriaki Iino

4

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13 January 2020

Marilyn G Farquhar

6

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language of work or name

English

0 references

publication date

1 July 2005

1 reference

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Proceedings of the National Academy of Sciences of the United States of America

13 January 2020

published in

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volume

102

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page(s)

9814-9819

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issue

28

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Nephrin forms a complex with adherens junction proteins and CASK in podocytes and in Madin-Darby canine kidney cells expressing nephrin

13 January 2020

cites work

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Neph1 and nephrin interaction in the slit diaphragm is an important determinant of glomerular permeability

19 March 2017

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Spectrin alpha II and beta II isoforms interact with high affinity at the tetramerization site

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JAM4, a junctional cell adhesion molecule interacting with a tight junction protein, MAGI-1

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The carboxyl terminus of Neph family members binds to the PDZ domain protein zonula occludens-1

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IQGAP1 is a component of Cdc42 signaling to the cytoskeleton

19 March 2017

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The glomerular epithelial cell anti-adhesin podocalyxin associates with the actin cytoskeleton through interactions with ezrin

19 March 2017

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Proteinuria and perinatal lethality in mice lacking NEPH1, a novel protein with homology to NEPHRIN

19 March 2017

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The membrane-associated guanylate kinase protein MAGI-1 binds megalin and is present in glomerular podocytes

19 March 2017

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Association of junctional adhesion molecule with calcium/calmodulin-dependent serine protein kinase (CASK/LIN-2) in human epithelial caco-2 cells

19 March 2017

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NPHS2, encoding the glomerular protein podocin, is mutated in autosomal recessive steroid-resistant nephrotic syndrome

19 March 2017

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Mutations in ACTN4, encoding alpha-actinin-4, cause familial focal segmental glomerulosclerosis

19 March 2017

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Three isoforms of synaptic scaffolding molecule and their characterization. Multimerization between the isoforms and their interaction with N-methyl-D-aspartate receptors and SAP90/PSD-95-associated protein

19 March 2017

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IQGAP1 and calmodulin modulate E-cadherin function

19 March 2017

1 reference

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A novel multiple PDZ domain-containing molecule interacting with N-methyl-D-aspartate receptors and neuronal cell adhesion proteins

19 March 2017

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Role of IQGAP1, a target of the small GTPases Cdc42 and Rac1, in regulation of E-cadherin- mediated cell-cell adhesion

19 March 2017

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Positionally cloned gene for a novel glomerular protein--nephrin--is mutated in congenital nephrotic syndrome

19 March 2017

1 reference

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IQGAP1, a Rac- and Cdc42-binding protein, directly binds and cross-links microfilaments

19 March 2017

1 reference

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CASK: a novel dlg/PSD95 homolog with an N-terminal calmodulin-dependent protein kinase domain identified by interaction with neurexins

19 March 2017

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IQGAP1, a calmodulin-binding protein with a rasGAP-related domain, is a potential effector for cdc42Hs

19 March 2017

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Interaction of alpha-actinin with the cadherin/catenin cell-cell adhesion complex via alpha-catenin

19 March 2017

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The altered glomerular filtration slits seen in puromycin aminonucleoside nephrosis and protamine sulfate-treated rats contain the tight junction protein ZO-1

19 March 2017

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Characterization of the interactions of the nephrin intracellular domain.

19 March 2017

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Nephrin strands contribute to a porous slit diaphragm scaffold as revealed by electron tomography

29 September 2017

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The immunoglobulin family member dendrite arborization and synapse maturation 1 (Dasm1) controls excitatory synapse maturation

29 September 2017

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Nectin-dependent localization of synaptic scaffolding molecule (S-SCAM) at the puncta adherentia junctions formed between the mossy fibre terminals and the dendrites of pyramidal cells in the CA3 area of the mouse hippocampus

29 September 2017

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29 September 2017

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29 September 2017

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Mice lacking the giant protocadherin mFAT1 exhibit renal slit junction abnormalities and a partially penetrant cyclopia and anophthalmia phenotype.

29 September 2017

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Genetic studies define MAGUK proteins as regulators of epithelial cell polarity

29 September 2017

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Interaction of synaptic scaffolding molecule and Beta -catenin.

29 September 2017

1 reference

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alpha -Catenin binds directly to spectrin and facilitates spectrin-membrane assembly in vivo

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1175008

Control of epithelial cell shape and polarity

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1175008

Biogenesis of polarized epithelial cells during kidney development in situ: roles of E-cadherin-mediated cell-cell adhesion and membrane cytoskeleton organization

29 September 2017

1 reference

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The catenin/cadherin adhesion system is localized in synaptic junctions bordering transmitter release zones.

29 September 2017

1 reference

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Identification and characterization of podocalyxin--the major sialoprotein of the renal glomerular epithelial cell

29 September 2017

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The tight junction protein ZO-1 is concentrated along slit diaphragms of the glomerular epithelium

29 September 2017

1 reference

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Identification of a membrane-cytoskeletal complex containing the cell adhesion molecule uvomorulin (E-cadherin), ankyrin, and fodrin in Madin-Darby canine kidney epithelial cells

29 September 2017

1 reference

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Monoclonal antibodies against membrane proteins of the rat glomerulus. Immunochemical specificity and immunofluorescence distribution of the antigens

29 September 2017

1 reference

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Diversity among tight junctions in rat kidney: glomerular slit diaphragms and endothelial junctions express only one isoform of the tight junction protein ZO-1

29 September 2017

1 reference

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Association of intercellular adhesion molecule-1 (ICAM-1) with actin-containing cytoskeleton and alpha-actinin

29 September 2017

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IQGAP1 promotes cell motility and invasion

29 September 2017

1 reference

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Role of nephrin in cell junction formation in human nephrogenesis

3 June 2018

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Localization of GTPases by indirect immunofluorescence and immunoelectron microscopy

3 June 2018

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Ankyrin binding activity shared by the neurofascin/L1/NrCAM family of nervous system cell adhesion molecules

3 June 2018

1 reference

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Ultrastructural organization of contractile and cytoskeletal proteins in glomerular podocytes of chicken, rat, and man.

3 June 2018

1 reference

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Differentiation of epithelial foot processes and filtration slits: sequential appearance of occluding junctions, epithelial polyanion, and slit membranes in developing glomeruli

3 June 2018

1 reference

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Global analyses of sumoylated proteins in Saccharomyces cerevisiae. Induction of protein sumoylation by cellular stresses

3 June 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.0504166102

Congenital nephrotic syndrome in mice lacking CD2-associated protein

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1175008

Nephrin strands contribute to a porous slit diaphragm scaffold as revealed by electron tomography

27 November 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.0504166102

Biogenesis of podocalyxin--the major glomerular sialoglycoprotein--in the newborn rat kidney

21 January 2018

1 reference

12 December 2020

FAT is a component of glomerular slit diaphragms

1 reference

12 December 2020

The glomerular slit diaphragm is a modified adherens junction

1 reference

12 December 2020

Alpha 3 beta 1 integrin has a crucial role in kidney and lung organogenesis

1 reference

12 December 2020

Alterations of the glomerular epithelium in acute aminonucleoside nephrosis. Evidence for formation of occluding junctions and epithelial cell detachment

1 reference

12 December 2020

Focal and segmental glomerulosclerosis in mice with podocyte-specific expression of mutant alpha-actinin-4

1 reference

12 December 2020

A simple, non-chromatographic procedure to purify immunoglobulins from serum and ascites fluid

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.0504166102

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15994232%20AND%20SRC:MED&resulttype=core&format=json

13 January 2020

ADS bibcode

2005PNAS..102.9814L

0 references

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15994232%20AND%20SRC:MED&resulttype=core&format=json

13 January 2020

2 references