Akt-mediated cardiomyocyte survival pathways are compromised by G alpha q-induced phosphoinositide 4,5-bisphosphate depletion (Q28571127)

2

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31 January 2017

Tong Zhang

3

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31 January 2017

Shigeki Miyamoto

4

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31 January 2017

John W. Adams

5

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31 January 2017

Gerald W. Dorn

6

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31 January 2017

Elizabeth A. Woodcock

7

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31 January 2017

Joan Heller Brown

Journal of Biological Chemistry

8

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31 January 2017

language of work or name

English

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publication date

10 October 2003

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31 January 2017

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31 January 2017

278

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31 January 2017

41

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31 January 2017

40343–40351

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31 January 2017

Myocardial expression of a constitutively active alpha 1B-adrenergic receptor in transgenic mice induces cardiac hypertrophy

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Transgenic mice with cardiac overexpression of alpha1B-adrenergic receptors. In vivo alpha1-adrenergic receptor-mediated regulation of beta-adrenergic signaling

21 January 2018

1 reference

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Progressive hypertrophy and heart failure in beta1-adrenergic receptor transgenic mice.

21 January 2018

1 reference

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Overexpression of angiotensin AT1 receptor transgene in the mouse myocardium produces a lethal phenotype associated with myocyte hyperplasia and heart block

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305964200

Enhanced Galphaq signaling: a common pathway mediates cardiac hypertrophy and apoptotic heart failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305964200

Transient cardiac expression of constitutively active Galphaq leads to hypertrophy and dilated cardiomyopathy by calcineurin-dependent and independent pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305964200

Targeted overexpression of protein kinase C beta2 isoform in myocardium causes cardiomyopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305964200

Cardiomyocyte apoptosis induced by Galphaq signaling is mediated by permeability transition pore formation and activation of the mitochondrial death pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305964200

Akt promotes survival of cardiomyocytes in vitro and protects against ischemia-reperfusion injury in mouse heart.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305964200

The role of phosphoinositide 3-kinase lipid products in cell function

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305964200

Akt/protein kinase B is regulated by autophosphorylation at the hypothetical PDK-2 site

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305964200

Regulation of protein kinase B and 4E-BP1 by oxidative stress in cardiac myocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305964200

Involvement of cardiotrophin-1 in cardiac myocyte-nonmyocyte interactions during hypertrophy of rat cardiac myocytes in vitro.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305964200

Loss of a gp130 cardiac muscle cell survival pathway is a critical event in the onset of heart failure during biomechanical stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305964200

Akt activation preserves cardiac function and prevents injury after transient cardiac ischemia in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305964200

Intracoronary, adenovirus-mediated Akt gene transfer in heart limits infarct size following ischemia-reperfusion injury in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305964200

Membrane-targeted phosphatidylinositol 3-kinase mimics insulin actions and induces a state of cellular insulin resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305964200

Cell cycle withdrawal promotes myogenic induction of Akt, a positive modulator of myocyte survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305964200

The phosphoinositide-dependent kinase, PDK-1, phosphorylates conventional protein kinase C isozymes by a mechanism that is independent of phosphoinositide 3-kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305964200

Cardiotrophin-1 phosphorylates akt and BAD, and prolongs cell survival via a PI3K-dependent pathway in cardiac myocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305964200

Cardiotrophin 1 (CT-1) inhibition of cardiac myocyte apoptosis via a mitogen-activated protein kinase-dependent pathway. Divergence from downstream CT-1 signals for myocardial cell hypertrophy

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305964200

A new phospholipase-C-calcium signalling pathway mediated by cyclic AMP and a Rap GTPase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305964200

Cellular signaling: pivoting around PDK-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305964200

Activation of the β1 isozyme of phospholipase C by α subunits of the Gq class of G proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305964200

Regulation of polyphosphoinositide-specific phospholipase C activity by purified Gq.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305964200

Identification of determinants in the alpha-subunit of Gq required for phospholipase C activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305964200

Physical and functional interactions of Galphaq with Rho and its exchange factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305964200

Transgenic Galphaq overexpression induces cardiac contractile failure in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305964200

Signaling pathways for cardiac hypertrophy and failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305964200

Low level of sarcolemmal phosphatidylinositol 4,5-bisphosphate in cardiomyopathic hamster (UM-X7.1) heart

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305964200

Glycoprotein 130 regulates cardiac myocyte survival in doxorubicin-induced apoptosis through phosphatidylinositol 3-kinase/Akt phosphorylation and Bcl-xL/caspase-3 interaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305964200

Activated Gαq Inhibits p110α Phosphatidylinositol 3-Kinase and Akt

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305964200

Localization and turnover of phosphatidylinositol 4,5-bisphosphate in caveolin-enriched membrane domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305964200

Cholesterol depletion delocalizes phosphatidylinositol bisphosphate and inhibits hormone-stimulated phosphatidylinositol turnover

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305964200

Expression of G qα and PLC-β in Scar and Border Tissue in Heart Failure Due to Myocardial Infarction

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305964200

21 January 2018

Identifiers

DOI

10.1074/JBC.M305964200

1 reference

Consolidated OpenCitations Corpus – April 2017

1290455

1290455

1 reference

Consolidated OpenCitations Corpus – April 2017

Consolidated OpenCitations Corpus – April 2017

1 reference