Akt promotes survival of cardiomyocytes in vitro and protects against ischemia-reperfusion injury in mouse heart. (Q39870130)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10673259%20AND%20SRC:MED&resulttype=core&format=json

4 November 2019

title

Akt promotes survival of cardiomyocytes in vitro and protects against ischemia-reperfusion injury in mouse heart (English)

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4 November 2019

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5

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4 November 2019

author name string

Y Fujio

1

1 reference

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4 November 2019

T Nguyen

2

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4 November 2019

D Wencker

3

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4 November 2019

R N Kitsis

4

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4 November 2019

language of work or name

English

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publication date

1 February 2000

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4 November 2019

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4 November 2019

volume

101

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4 November 2019

page(s)

660-667

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4 November 2019

issue

6

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Akt mediates cytoprotection of endothelial cells by vascular endothelial growth factor in an anchorage-dependent manner

4 November 2019

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3627349

Loss of a gp130 cardiac muscle cell survival pathway is a critical event in the onset of heart failure during biomechanical stress

22 September 2017

1 reference

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Dissociation of cytokine-induced phosphorylation of Bad and activation of PKB/akt: involvement of MEK upstream of Bad phosphorylation

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3627349

Requirement for activation of the serine-threonine kinase Akt (protein kinase B) in insulin stimulation of protein synthesis but not of glucose transport

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3627349

Adenoviral delivery of E2F-1 directs cell cycle reentry and p53-independent apoptosis in postmitotic adult myocardium in vivo

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3627349

Overexpression of insulin-like growth factor-1 in mice protects from myocyte death after infarction, attenuating ventricular dilation, wall stress, and cardiac hypertrophy

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3627349

Interleukin 3-dependent survival by the Akt protein kinase

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3627349

Myocyte apoptosis during acute myocardial infarction in the mouse localizes to hypoxic regions but occurs independently of p53

22 September 2017

1 reference

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Signalling through the lipid products of phosphoinositide-3-OH kinase

22 September 2017

1 reference

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Signals through gp130 upregulate bcl-x gene expression via STAT1-binding cis-element in cardiac myocytes.

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3627349

Mechanism of activation of protein kinase B by insulin and IGF-1

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3627349

An efficient and flexible system for construction of adenovirus vectors with insertions or deletions in early regions 1 and 3.

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3627349

MyoD-induced expression of p21 inhibits cyclin-dependent kinase activity upon myocyte terminal differentiation

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3627349

Cardioprotective effect of insulin-like growth factor I in myocardial ischemia followed by reperfusion

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3627349

Protein kinase B and rac are activated in parallel within a phosphatidylinositide 3OH-kinase-controlled signaling pathway

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3627349

Cloning, chromosomal localization and expression analysis of the mouse Akt2 oncogene.

25 September 2017

1 reference

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Death by design. Programmed cell death in cardiovascular biology and disease

25 September 2017

1 reference

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Protein kinase B (c-Akt): a multifunctional mediator of phosphatidylinositol 3-kinase activation.

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3627349

Regulation of cardiomyocyte apoptotic signaling by insulin-like growth factor I.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3627349

Ventricular myocytes are not terminally differentiated in the adult mammalian heart.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3627349

Cardiotrophin 1 (CT-1) inhibition of cardiac myocyte apoptosis via a mitogen-activated protein kinase-dependent pathway. Divergence from downstream CT-1 signals for myocardial cell hypertrophy

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3627349

Apoptotic and necrotic myocyte cell deaths are independent contributing variables of infarct size in rats.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3627349

Insulin-like Growth Factor-I Rapidly Activates Multiple Signal Transduction Pathways in Cultured Rat Cardiac Myocytes

20 August 2018

1 reference

12 December 2020

Activation of phosphatidylinositol 3-kinase through glycoprotein 130 induces protein kinase B and p70 S6 kinase phosphorylation in cardiac myocytes

1 reference

12 December 2020

Survey of studies examining mammalian cardiomyocyte DNA synthesis

1 reference

12 December 2020

Metabolic modulation of acute myocardial infarction. The ECLA (Estudios Cardiológicos Latinoamérica) Collaborative Group

1 reference

12 December 2020

Apoptosis in ischemic and reperfused rat myocardium

1 reference

12 December 2020

Identifiers

DOI

10.1161/01.CIR.101.6.660

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10673259%20AND%20SRC:MED&resulttype=core&format=json

4 November 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10673259%20AND%20SRC:MED&resulttype=core&format=json

4 November 2019

1 reference