Diacylglycerol acyltranferase 1 anti-sense oligonucleotides reduce hepatic fibrosis in mice with nonalcoholic steatohepatitis (Q28572478)

31 January 2017

title

Diacylglycerol acyltranferase 1 anti-sense oligonucleotides reduce hepatic fibrosis in mice with nonalcoholic steatohepatitis (English)

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31 January 2017

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Kanji Yamaguchi

1

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31 January 2017

Liu Yang

2

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31 January 2017

Shannon McCall

3

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31 January 2017

Jiawen Huang

4

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31 January 2017

Xing Xian Yu

5

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31 January 2017

Sanjay K. Pandey

6

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31 January 2017

Sanjay Bhanot

7

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Brett P. Monia

8

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Yin-Xiong Li

9

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Anna Mae Diehl

10

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31 January 2017

language of work or name

English

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publication date

1 February 2008

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volume

47

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issue

2

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page(s)

625–635

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Seminars in medicine of the Beth Israel Hospital, Boston. The cellular basis of hepatic fibrosis. Mechanisms and treatment strategies

31 January 2017

cites work

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7 January 2021

Differential modulation of rat hepatic stellate phenotype by natural and synthetic retinoids

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Regulation of hepatic retinol metabolism: perspectives from studies on vitamin A status

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Disruption of the lecithin:retinol acyltransferase gene makes mice more susceptible to vitamin A deficiency

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Retinoid absorption and storage is impaired in mice lacking lecithin:retinol acyltransferase (LRAT).

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Ito cell expression of a nuclear retinoic acid receptor

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Identification of a retinoic acid responsive element in the retinoic acid receptor beta gene

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A human retinoic acid receptor which belongs to the family of nuclear receptors

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Effect of retinoic acid on the enhancing effect of acetaldehyde on mouse type I collagen expression

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Regulation of the murine alpha(2)(I) collagen promoter by retinoic acid and retinoid X receptors

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Regulation of alpha 2(I) collagen expression in stellate cells by retinoic acid and retinoid X receptors through interactions with their cofactors

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7 January 2021

Acyl-CoA: retinol acyltransferase (ARAT) and lecithin:retinol acyltransferase (LRAT) activation during the lipocyte phenotype induction in hepatic stellate cells

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7 January 2021

The triacylglycerol synthesis enzyme DGAT1 also catalyzes the synthesis of diacylglycerols, waxes, and retinyl esters

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7 January 2021

Inhibition of triglyceride synthesis as a treatment strategy for obesity: lessons from DGAT1-deficient mice

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7 January 2021

Inhibiting triglyceride synthesis improves hepatic steatosis but exacerbates liver damage and fibrosis in obese mice with nonalcoholic steatohepatitis.

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Sustained activation of Rac1 in hepatic stellate cells promotes liver injury and fibrosis in mice.

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Interleukin-15 increases hepatic regenerative activity

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Role for hedgehog signaling in hepatic stellate cell activation and viability

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Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

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Dose-dependent inhibition of hepatic fibrosis in mice by a TGF-beta soluble receptor: implications for antifibrotic therapy

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Developmental changes in endogenous retinoids during pregnancy and embryogenesis in the mouse.

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Determination of vitamins A and E in milk samples by fluorescence in micellar media.

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Validation of a screening method for the simultaneous identification of fat-soluble and water-soluble vitamins (A, E, B1, B2 and B6) in an aqueous micellar medium of hexadecyltrimethylammonium chloride.

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7 January 2021

Regulation of hepatic lecithin:retinol acyltransferase activity by retinoic acid receptor-selective retinoids

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Auto-regulation of retinoic acid biosynthesis through regulation of retinol esterification in human keratinocytes

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Opposing effects of retinoic acid on cell growth result from alternate activation of two different nuclear receptors

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Retinol uptake and metabolism, and cellular retinol binding protein expression in an in vitro model of hepatic stellate cells.

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Cellular retinol-binding protein I is essential for vitamin A homeostasis.

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Fatty acyl CoA-dependent and -independent retinol esterification by rat liver and lactating mammary gland microsomes.

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Regulation of vitamin A transport into cultured stellate cells of rat liver: studies by anchored cell analysis and sorting system

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Suppression of diacylglycerol acyltransferase-2 (DGAT2), but not DGAT1, with antisense oligonucleotides reverses diet-induced hepatic steatosis and insulin resistance

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7 January 2021

Nonalcoholic fatty liver disease: predisposing factors and the role of nutrition

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The role of acyl-CoA:diacylglycerol acyltransferase (DGAT) in energy metabolism

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7 January 2021

Increased very low density lipoprotein secretion and gonadal fat mass in mice overexpressing liver DGAT1.

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Antisense oligonucleotide reduction of DGAT2 expression improves hepatic steatosis and hyperlipidemia in obese mice

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Identifiers

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31 January 2017

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