CD2AP in mouse and human podocytes controls a proteolytic program that regulates cytoskeletal structure and cellular survival (Q28572534)

31 January 2017

title

CD2AP in mouse and human podocytes controls a proteolytic program that regulates cytoskeletal structure and cellular survival (English)

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Transforming growth factor, beta 1

31 January 2017

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GOA release 2020-03-11

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GOA release 2020-03-11

CD2-associated protein

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GOA release 2020-03-11

13

Florian Grahammer

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Mario Schiffer

object named as

Mario Schiffer

14

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Thomas Reinheckel

object named as

Thomas Reinheckel

16

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Tobias B Huber

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ORCID Public Data File 2021

Changli Wei

6

object named as

Changli Wei

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31 January 2017

26

Sanja Sever

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31 January 2017

Suma Yaddanapudi

1

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31 January 2017

Mehmet M. Altintas

2

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31 January 2017

Andreas D. Kistler

3

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31 January 2017

Isabel Fernandez

4

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31 January 2017

Clemens C. Möller

5

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31 January 2017

Vasil Peev

7

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31 January 2017

Jan B. Flesche

8

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31 January 2017

Anna-Lena Forst

9

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31 January 2017

Jing Li

10

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31 January 2017

Jaakko Patrakka

11

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31 January 2017

Zhijie Xiao

12

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31 January 2017

Tobias Lohmüller

15

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Changkyu Gu

17

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31 January 2017

Tobias B. Huber

18

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31 January 2017

Wenjun Ju

19

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31 January 2017

Markus Bitzer

20

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Maria P. Rastaldi

21

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Phillip Ruiz

22

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Karl Tryggvason

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Andrey S. Shaw

24

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31 January 2017

Christian Faul

25

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31 January 2017

Jochen Reiser

27

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31 January 2017

language of work or name

English

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publication date

1 October 2011

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Journal of Clinical Investigation

31 January 2017

published in

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31 January 2017

volume

121

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31 January 2017

issue

10

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31 January 2017

page(s)

3965–3980

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describes a project that uses

31 January 2017

ImageJ

1 reference

Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3195478/fullTextXML

inferred from PubMed Central ID database lookup

cites work

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ZHX proteins regulate podocyte gene expression during the development of nephrotic syndrome

19 March 2017

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Nck adaptor proteins link nephrin to the actin cytoskeleton of kidney podocytes

19 March 2017

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19 March 2017

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19 March 2017

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19 March 2017

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19 March 2017

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Podocyte-secreted angiopoietin-like-4 mediates proteinuria in glucocorticoid-sensitive nephrotic syndrome

7 April 2017

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29 September 2017

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c-mip impairs podocyte proximal signaling and induces heavy proteinuria

29 September 2017

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TbetaRI independently activates Smad- and CD2AP-dependent pathways in podocytes

29 September 2017

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29 September 2017

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Renal gene and protein expression signatures for prediction of kidney disease progression

29 September 2017

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CD2AP mutations are associated with sporadic nephrotic syndrome and focal segmental glomerulosclerosis (FSGS).

29 September 2017

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The actin cytoskeleton of kidney podocytes is a direct target of the antiproteinuric effect of cyclosporine A.

29 September 2017

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Proteolytic processing of dynamin by cytoplasmic cathepsin L is a mechanism for proteinuric kidney disease

29 September 2017

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Nuclear relocation of the nephrin and CD2AP-binding protein dendrin promotes apoptosis of podocytes

29 September 2017

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29 September 2017

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Bigenic mouse models of focal segmental glomerulosclerosis involving pairwise interaction of CD2AP, Fyn, and synaptopodin

29 September 2017

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29 September 2017

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Nephrin ectodomain engagement results in Src kinase activation, nephrin phosphorylation, Nck recruitment, and actin polymerization

29 September 2017

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29 September 2017

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Podocyte migration during nephrotic syndrome requires a coordinated interplay between cathepsin L and alpha3 integrin

29 September 2017

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Signaling at the slit diaphragm

29 September 2017

1 reference

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Induction of B7-1 in podocytes is associated with nephrotic syndrome

29 September 2017

1 reference

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Toward computer-based cleavage site prediction of cysteine endopeptidases

29 September 2017

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29 September 2017

1 reference

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CD2AP localizes to the slit diaphragm and binds to nephrin via a novel C-terminal domain

29 September 2017

1 reference

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Apoptosis in podocytes induced by TGF-beta and Smad7

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3195478

The role of the podocyte in glomerulosclerosis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3195478

Rearrangements of the cytoskeleton and cell contacts induce process formation during differentiation of conditionally immortalized mouse podocyte cell lines.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3195478

Deletion of Smad2 in mouse liver reveals novel functions in hepatocyte growth and differentiation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3195478

Nephrin localizes to the slit pore of the glomerular epithelial cell

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3195478

Multi-step processing of procathepsin L in vitro

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3195478

Modification of kidney barrier function by the urokinase receptor.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3195478

Nck links nephrin to actin in kidney podocytes.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3195478

Glucose-induced reactive oxygen species cause apoptosis of podocytes and podocyte depletion at the onset of diabetic nephropathy

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3195478

Podocyte depletion causes glomerulosclerosis: diphtheria toxin-induced podocyte depletion in rats expressing human diphtheria toxin receptor transgene.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3195478

CD2-associated protein (CD2AP) expression in podocytes rescues lethality of CD2AP deficiency

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3195478

A novel role for the adaptor molecule CD2-associated protein in transforming growth factor-beta-induced apoptosis

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3195478

CD2-associated protein directly interacts with the actin cytoskeleton.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3195478

Congenital nephrotic syndrome in mice lacking CD2-associated protein

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3195478

Transgenic mice with increased plasma levels of TGF-beta 1 develop progressive renal disease

27 November 2018

1 reference

12 December 2020

Focal segmental glomerulosclerosis in a patient homozygous for a CD2AP mutation

1 reference

12 December 2020

Dendrin location in podocytes is associated with disease progression in animal and human glomerulopathy

1 reference

12 December 2020

Tracer studies in the rat demonstrate misdirected filtration and peritubular filtrate spreading in nephrons with segmental glomerulosclerosis

1 reference

12 December 2020

Identifiers

1 reference

release_mxxqmgvlcrgmpoferw457exire

31 January 2017

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/mxxqmgvlcrgmpoferw457exire

24 November 2022

mapped directly with Wikidata item

PMC publication ID

3195478

0 references

1 reference