Attenuation of the activity of the cAMP-specific phosphodiesterase PDE4A5 by interaction with the immunophilin XAP2 (Q28573529)

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author name string

Graeme B. Bolger

1

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31 January 2017

Alexander H. Peden

2

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31 January 2017

Michael R. Steele

3

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31 January 2017

Carolynn MacKenzie

4

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31 January 2017

Derek A. Wallace

6

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31 January 2017

Elaine Huston

7

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31 January 2017

George S. Baillie

Journal of Biological Chemistry

8

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31 January 2017

language of work or name

English

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publication date

29 August 2003

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31 January 2017

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31 January 2017

278

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31 January 2017

35

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31 January 2017

33351–33363

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31 January 2017

Cyclic nucleotide research -- still expanding after half a century

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The novel long PDE4A10 cyclic AMP phosphodiesterase shows a pattern of expression within brain that is distinct from the long PDE4A5 and short PDE4A1 isoforms.

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In addition to the SH3 binding region, multiple regions within the N-terminal noncatalytic portion of the cAMP-specific phosphodiesterase, PDE4A5, contribute to its intracellular targeting

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The cAMP-specific phosphodiesterase PDE4A5 is cleaved downstream of its SH3 interaction domain by caspase-3. Consequences for altered intracellular distribution

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The SH3 domain of Src tyrosyl protein kinase interacts with the N-terminal splice region of the PDE4A cAMP-specific phosphodiesterase RPDE-6 (RNPDE4A5)

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Association with the SRC family tyrosyl kinase LYN triggers a conformational change in the catalytic region of human cAMP-specific phosphodiesterase HSPDE4A4B. Consequences for rolipram inhibition

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A peripheral and an intrinsic enzyme constitute the cyclic AMP phosphodiesterase activity of rat liver plasma membranes

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Long PDE4 cAMP specific phosphodiesterases are activated by protein kinase A-mediated phosphorylation of a single serine residue in Upstream Conserved Region 1 (UCR1)

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Identifiers

DOI

10.1074/JBC.M303269200

1 reference

Consolidated OpenCitations Corpus – April 2017

3945258

3945258

1 reference

Consolidated OpenCitations Corpus – April 2017

Consolidated OpenCitations Corpus – April 2017

1 reference