FE65 as a link between VLDLR and APP to regulate their trafficking and processing (Q28573687)

31 January 2017

title

FE65 as a link between VLDLR and APP to regulate their trafficking and processing (English)

1 reference

31 January 2017

1

Sonya B. Dumanis

1 reference

31 January 2017

10

Yoo-Hun Suh

1 reference

31 January 2017

Kelly A. Chamberlain

2

1 reference

31 January 2017

Yoo Jin Sohn

3

1 reference

31 January 2017

Young Jin Lee

4

1 reference

31 January 2017

Suzanne Y. Guénette

5

1 reference

31 January 2017

Toshiharu Suzuki

6

1 reference

31 January 2017

Paul M. Mathews

7

1 reference

31 January 2017

Daniel Ts Pak

8

1 reference

31 January 2017

G. William Rebeck

9

1 reference

31 January 2017

Hee-Sae Park

11

1 reference

31 January 2017

Hyang-Sook Hoe

12

1 reference

31 January 2017

publication date

19 March 2012

1 reference

Molecular Neurodegeneration

31 January 2017

published in

1 reference

31 January 2017

volume

7

1 reference

31 January 2017

page(s)

9

1 reference

LRAD3, a novel low-density lipoprotein receptor family member that modulates amyloid precursor protein trafficking

31 January 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3379943

The neuronal sortilin-related receptor SORL1 is genetically associated with Alzheimer disease

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3379943

Essential roles for the FE65 amyloid precursor protein-interacting proteins in brain development

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3379943

Regulation of ApoE receptor proteolysis by ligand binding

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3379943

Cleavage of amyloid-beta precursor protein and amyloid-beta precursor-like protein by BACE 1

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3379943

Reelin and ApoE receptors cooperate to enhance hippocampal synaptic plasticity and learning

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3379943

The gamma -secretase-cleaved C-terminal fragment of amyloid precursor protein mediates signaling to the nucleus

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3379943

A transcriptionally [correction of transcriptively] active complex of APP with Fe65 and histone acetyltransferase Tip60

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3379943

The beta-amyloid precursor protein functions as a cytosolic anchoring site that prevents Fe65 nuclear translocation

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3379943

Reelin is a ligand for lipoprotein receptors

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3379943

Regulation of beta-amyloid secretion by FE65, an amyloid protein precursor-binding protein

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3379943

Interaction of cytosolic adaptor proteins with neuronal apolipoprotein E receptors and the amyloid precursor protein

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3379943

The WW domain of neural protein FE65 interacts with proline-rich motifs in Mena, the mammalian homolog of Drosophila enabled

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3379943

The intracellular cytoplasmic domain of the Alzheimer's disease amyloid precursor protein interacts with phosphotyrosine-binding domain proteins in the yeast two-hybrid system

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3379943

cDNA cloning and chromosome mapping of the human Fe65 gene: interaction of the conserved cytoplasmic domains of the human beta-amyloid precursor protein and its homologues with the mouse Fe65 protein

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3379943

The phosphotyrosine interaction domains of X11 and FE65 bind to distinct sites on the YENPTY motif of amyloid precursor protein

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3379943

Evidence that production and release of amyloid beta-protein involves the endocytic pathway

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3379943

Behavioral and anatomical deficits in mice homozygous for a modified beta-amyloid precursor protein gene

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3379943

APP and APLP2 are essential at PNS and CNS synapses for transmission, spatial learning and LTP.

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3379943

ApoE receptor 2 regulates synapse and dendritic spine formation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3379943

Resveratrol inhibits pathologic retinal neovascularization in Vldlr(-/-) mice

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3379943

The E3 ubiquitin ligase IDOL induces the degradation of the low density lipoprotein receptor family members VLDLR and ApoER2.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3379943

S100a9 knockdown decreases the memory impairment and the neuropathology in Tg2576 mice, AD animal model

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3379943

The APP-interacting protein FE65 is required for hippocampus-dependent learning and long-term potentiation.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3379943

ApoER2 expression increases Abeta production while decreasing Amyloid Precursor Protein (APP) endocytosis: Possible role in the partitioning of APP into lipid rafts and in the regulation of gamma-secretase activity.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3379943

Intracellular domains of amyloid precursor-like protein 2 interact with CP2 transcription factor in the nucleus and induce glycogen synthase kinase-3beta expression

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3379943

Rapid endocytosis of the low density lipoprotein receptor-related protein modulates cell surface distribution and processing of the beta-amyloid precursor protein.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3379943

The low density lipoprotein receptor-related protein 1B retains beta-amyloid precursor protein at the cell surface and reduces amyloid-beta peptide production

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3379943

Increased soluble amyloid-beta peptide and memory deficits in amyloid model mice overexpressing the low-density lipoprotein receptor-related protein

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3379943

Malformation of the radial glial scaffold in the dentate gyrus of reeler mice, scrambler mice, and ApoER2/VLDLR-deficient mice

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3379943

The cytoplasmic domain of the LDL receptor-related protein regulates multiple steps in APP processing

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3379943

Direct visualization of the gamma secretase-generated carboxyl-terminal domain of the amyloid precursor protein: association with Fe65 and translocation to the nucleus

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3379943

The Alzheimer amyloid precursor protein (APP) and FE65, an APP-binding protein, regulate cell movement

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3379943

hFE65L influences amyloid precursor protein maturation and secretion

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3379943

Protein interactions among Fe65, the low-density lipoprotein receptor-related protein, and the amyloid precursor protein

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3379943

Beta amyloid-independent role of amyloid precursor protein in generation and maintenance of dendritic spines

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3379943

Expression of the Fe65 adapter protein in adult and developing mouse brain.

3 June 2018

1 reference

https://api.crossref.org/works/10.1186%2F1750-1326-7-9

Dissection of amyloid-beta precursor protein-dependent transcriptional transactivation

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1750-1326-7-9

Expression of human FE65 in amyloid precursor protein transgenic mice is associated with a reduction in beta-amyloid load

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1750-1326-7-9

FE65 constitutes the functional link between the low-density lipoprotein receptor-related protein and the amyloid precursor protein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1750-1326-7-9

The intracellular domain of the low density lipoprotein receptor-related protein modulates transactivation mediated by amyloid precursor protein and Fe65.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1750-1326-7-9

Modulation of beta-amyloid precursor protein processing by the low density lipoprotein receptor-related protein (LRP). Evidence that LRP contributes to the pathogenesis of Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1750-1326-7-9

Amyloid precursor protein knockout mice show age-dependent deficits in passive avoidance learning.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1750-1326-7-9

C-terminal fragments of amyloid precursor protein exert neurotoxicity by inducing glycogen synthase kinase-3beta expression.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3379943

FE65 Interaction with the ApoE Receptor ApoEr2

27 November 2018

1 reference

https://api.crossref.org/works/10.1186%2F1750-1326-7-9

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1750-1326-7-9

The transcriptional activity of the APP intracellular domain-Fe65 complex is inhibited by activation of the NF-kappaB pathway

21 January 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/22429478

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Mutagenesis identifies new signals for beta-amyloid precursor protein endocytosis, turnover, and the generation of secreted fragments, including Abeta42

1 reference

https://pubmed.ncbi.nlm.nih.gov/22429478

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1186/1750-1326-7-9

1 reference

Dimensions Publication ID

1030513084

0 references

1 reference

1 reference

1 reference