Dissection of amyloid-beta precursor protein-dependent transcriptional transactivation. (Q47880848)

6 February 2018

title

Dissection of amyloid-beta precursor protein-dependent transcriptional transactivation. (English)

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6 February 2018

2

Thomas C Südhof

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6 February 2018

Xinwei Cao

1

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6 February 2018

language of work or name

English

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publication date

24 March 2004

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6 February 2018

Journal of Biological Chemistry

number of pages

11

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published in

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6 February 2018

volume

279

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6 February 2018

page(s)

24601-24611

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6 February 2018

issue

23

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6 February 2018

The beta-amyloid precursor protein (APP) and Alzheimer's disease: does the tail wag the dog?

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The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics

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Identification of a mouse brain cDNA that encodes a protein related to the Alzheimer disease-associated amyloid beta protein precursor

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Isolation and characterization of APLP2 encoding a homologue of the Alzheimer's associated amyloid beta protein precursor

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Processing of beta-amyloid precursor-like protein-1 and -2 by gamma-secretase regulates transcription

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gamma-Secretase cleavage and binding to FE65 regulate the nuclear translocation of the intracellular C-terminal domain (ICD) of the APP family of proteins

21 January 2018

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Cleavage of amyloid-beta precursor protein and amyloid-beta precursor-like protein by BACE 1

21 January 2018

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Mice deficient for the amyloid precursor protein gene.

21 January 2018

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Generation of APLP2 KO mice and early postnatal lethality in APLP2/APP double KO mice

21 January 2018

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A transcriptionally [correction of transcriptively] active complex of APP with Fe65 and histone acetyltransferase Tip60

21 January 2018

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Involvement of the TIP60 histone acetylase complex in DNA repair and apoptosis

21 January 2018

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Deficiency of presenilin-1 inhibits the normal cleavage of amyloid precursor protein

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Immunohistochemical localization of beta-amyloid precursor protein sequences in Alzheimer and normal brain tissue by light and electron microscopy.

21 January 2018

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Expression of the Fe65 adapter protein in adult and developing mouse brain.

21 January 2018

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The intracellular domain of the beta-amyloid precursor protein is stabilized by Fe65 and translocates to the nucleus in a notch-like manner

21 January 2018

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Notch-1 signalling requires ligand-induced proteolytic release of intracellular domain

21 January 2018

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A novel regulatory mechanism in the mitogen-activated protein (MAP) kinase cascade. Role of nuclear export signal of MAP kinase kinase.

21 January 2018

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Identification of a signal for rapid export of proteins from the nucleus

21 January 2018

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Neurexins: synaptic cell surface proteins related to the alpha-latrotoxin receptor and laminin

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Requirements for presenilin-dependent cleavage of notch and other transmembrane proteins.

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PIP(2) and proteins: interactions, organization, and information flow

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The Alzheimer amyloid precursor protein (APP) and FE65, an APP-binding protein, regulate cell movement

21 January 2018

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Exchange of N-CoR corepressor and Tip60 coactivator complexes links gene expression by NF-kappaB and beta-amyloid precursor protein

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Distinct intramembrane cleavage of the beta-amyloid precursor protein family resembling gamma-secretase-like cleavage of Notch

21 January 2018

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11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M402248200

A ligand-induced extracellular cleavage regulates gamma-secretase-like proteolytic activation of Notch1

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M402248200

Mice with combined gene knock-outs reveal essential and partially redundant functions of amyloid precursor protein family members.

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M402248200

The beta-amyloid precursor protein functions as a cytosolic anchoring site that prevents Fe65 nuclear translocation

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M402248200

The amyloid precursor protein and its regulatory protein, FE65, in growth cones and synapses in vitro and in vivo

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11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M402248200

Identifiers

DOI

10.1074/JBC.M402248200

1 reference

6 February 2018

PubMed ID

15044485

1 reference

6 February 2018