Increased expression and activation of c-Jun contributes to human amylin-induced apoptosis in pancreatic islet beta-cells (Q28574483)

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2901044-6

Islet amyloid formed from diabetes-associated peptide may be pathogenic in type-2 diabetes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2901044-6

Amyloid fibrils in human insulinoma and islets of Langerhans of the diabetic cat are derived from a neuropeptide-like protein also present in normal islet cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2901044-6

Islet amyloid and type 2 diabetes mellitus

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2901044-6

A novel peptide in the calcitonin gene related peptide family as an amyloid fibril protein in the endocrine pancreas

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2901044-6

Pancreatic islet cell toxicity of amylin associated with type-2 diabetes mellitus

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2901044-6

Pancreatic amylin and calcitonin gene-related peptide cause resistance to insulin in skeletal muscle in vitro.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2901044-6

Spontaneous diabetes mellitus in transgenic mice expressing human islet amyloid polypeptide

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2901044-6

Promotion of beta-structure by interaction of diabetes associated polypeptide (amylin) with phosphatidylcholine

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2901044-6

Watching amyloid fibrils grow by time-lapse atomic force microscopy

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2901044-6

Amyloid Fibril Formation from Full-Length and Fragments of Amylin

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2901044-6

Syntheses, structures and anorectic effects of human and rat amylin

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2901044-6

Amylin and the amylin gene: structure, function and relationship to islet amyloid and to diabetes mellitus

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2901044-6

Islet amyloid polypeptide: pinpointing amino acid residues linked to amyloid fibril formation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2901044-6

Identification of a penta- and hexapeptide of islet amyloid polypeptide (IAPP) with amyloidogenic and cytotoxic properties

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2901044-6

Islet amyloid formation associated with hyperglycemia in transgenic mice with pancreatic beta cell expression of human islet amyloid polypeptide.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2901044-6

Islet amyloid: a long-recognized but underappreciated pathological feature of type 2 diabetes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2901044-6

Extensive islet amyloid formation is induced by development of Type II diabetes mellitus and contributes to its progression: pathogenesis of diabetes in a mouse model

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2901044-6

Sex steroids do not prevent amylin-induced apoptosis in human cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2901044-6

Ultrastructural evidence that apoptosis is the mechanism by which human amylin evokes death in RINm5F pancreatic islet beta-cells.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2901044-6

Islet amyloid-associated diabetes in obese A(vy)/a mice expressing human islet amyloid polypeptide.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2901044-6

Induction of apoptosis by human amylin in RINm5F islet beta-cells is associated with enhanced expression of p53 and p21WAF1/CIP1.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2901044-6

Intra- and extracellular amyloid fibrils are formed in cultured pancreatic islets of transgenic mice expressing human islet amyloid polypeptide

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2901044-6

Intracellular amyloidogenesis by human islet amyloid polypeptide induces apoptosis in COS-1 cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2901044-6

Different sensitivity to the cytotoxic action of IAPP fibrils in two insulin-producing cell lines, HIT-T15 and RINm5F cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2901044-6

The mechanism of islet amyloid polypeptide toxicity is membrane disruption by intermediate-sized toxic amyloid particles.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2901044-6

Pore formation by the cytotoxic islet amyloid peptide amylin

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2901044-6

Role of Ca2+ in apoptosis evoked by human amylin in pancreatic islet beta-cells.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2901044-6

Induction of apoptosis in fibroblasts by c-myc protein

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2901044-6

ATF-2 phosphorylation in apoptotic neuronal death.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2901044-6

Is c-Jun involved in nerve cell death following status epilepticus and hypoxic-ischaemic brain injury?

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2901044-6

Altered gene expression in neurons during programmed cell death: identification of c-jun as necessary for neuronal apoptosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2901044-6

A c-Jun dominant negative mutant protects sympathetic neurons against programmed cell death

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2901044-6

The role of inducible transcription factors in apoptotic nerve cell death

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2901044-6

The regulation of AP-1 activity by mitogen-activated protein kinases

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2901044-6

Transcription factor AP-1 regulation by mitogen-activated protein kinase signal transduction pathways.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2901044-6

Selective interaction of JNK protein kinase isoforms with transcription factors

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2901044-6

Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2901044-6

The stress-activated protein kinase pathway mediates cell death following injury induced by cis-platinum, UV irradiation or heat

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2901044-6

CEP-1347/KT-7515, an inhibitor of SAPK/JNK pathway activation, promotes survival and blocks multiple events associated with Abeta-induced cortical neuron apoptosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2901044-6

beta-Amyloid-induced neuronal apoptosis requires c-Jun N-terminal kinase activation.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2901044-6

The c-Jun amino-terminal kinase pathway is preferentially activated by interleukin-1 and controls apoptosis in differentiating pancreatic beta-cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2901044-6

c-Jun promotes neurite outgrowth and survival in PC12 cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2901044-6

Correlation between sustained c-Jun N-terminal protein kinase activation and apoptosis induced by tumor necrosis factor-alpha in rat mesangial cells.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2901044-6

Complex functions of AP-1 transcription factors in differentiation and survival of PC12 cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2901044-6

Transcriptional activation of c-jun during the G0/G1 transition in mouse fibroblasts

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2901044-6

Social controls on cell survival and cell death

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2901044-6

Apoptosis in the pathogenesis and treatment of disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2901044-6

Beta-cell gene expression and functional characterisation of the human insulinoma cell line CM.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2901044-6

The jun proto-oncogene is positively autoregulated by its product, Jun/AP-1

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2901044-6

Signal transduction pathways regulated by mitogen-activated/extracellular response kinase kinase kinase induce cell death

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2901044-6

Signal transduction by the c-Jun N-terminal kinase (JNK)--from inflammation to development

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2901044-6

The role of c-Jun N-terminal kinase (JNK) in apoptosis induced by ultraviolet C and gamma radiation. Duration of JNK activation may determine cell death and proliferation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2901044-6

Stress-induced activation of c-Jun N-terminal kinase in sensory ganglion neurons: accumulation in nuclear domains enriched in splicing factors and distribution in perichromatin fibrils.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2901044-6

The stress-activated protein kinase subfamily of c-Jun kinases

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2901044-6