Thrombospondin 1 acts as a strong promoter of transforming growth factor beta effects via two distinct mechanisms in hepatic stellate cells (Q28575592)

31 January 2017

title

Thrombospondin 1 acts as a strong promoter of transforming growth factor beta effects via two distinct mechanisms in hepatic stellate cells (English)

1 reference

31 January 2017

K. Breitkopf

1

1 reference

31 January 2017

I. Sawitza

2

1 reference

31 January 2017

J. H. Westhoff

3

1 reference

31 January 2017

L. Wickert

4

1 reference

31 January 2017

S. Dooley

5

1 reference

31 January 2017

A. M. Gressner

6

1 reference

31 January 2017

language of work or name

English

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publication date

1 May 2005

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31 January 2017

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31 January 2017

volume

54

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31 January 2017

issue

5

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31 January 2017

page(s)

673–681

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Tumor necrosis factor-alpha inhibits transforming growth factor-beta /Smad signaling in human dermal fibroblasts via AP-1 activation

31 January 2017

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The integrin alpha v beta 6 binds and activates latent TGF beta 1: a mechanism for regulating pulmonary inflammation and fibrosis

17 March 2017

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Thrombospondin-1 is a major activator of TGF-beta1 in vivo

17 March 2017

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Mice that lack thrombospondin 2 display connective tissue abnormalities that are associated with disordered collagen fibrillogenesis, an increased vascular density, and a bleeding diathesis

17 March 2017

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Interaction of platelet-derived growth factor with thrombospondin 1

17 March 2017

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Analysis of the promoter and transcription start sites of the human thrombospondin 2 gene (THBS2)

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Direct binding of Smad3 and Smad4 to critical TGF beta-inducible elements in the promoter of human plasminogen activator inhibitor-type 1 gene

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Antisense oligonucleotides against thrombospondin-1 inhibit activation of tgf-beta in fibrotic renal disease in the rat in vivo.

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Thrombospondin-1 promotes proliferative healing through stabilization of PDGF.

29 September 2017

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PDGF and signal transduction in hepatic stellate cells

29 September 2017

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Antisense-mediated reduction in thrombospondin-1 expression reduces cell motility in malignant glioma cells

29 September 2017

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29 September 2017

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Thrombospondin-1 is required for normal murine pulmonary homeostasis and its absence causes pneumonia

29 September 2017

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Requirement for transglutaminase in the activation of latent transforming growth factor-beta in bovine endothelial cells

29 September 2017

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Cell-specific expression of transforming growth factor-beta in rat liver. Evidence for autocrine regulation of hepatocyte proliferation

29 September 2017

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29 September 2017

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29 September 2017

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Platelet-derived growth factor and heparin-like glycosaminoglycans regulate thrombospondin synthesis and deposition in the matrix by smooth muscle cells

29 September 2017

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29 September 2017

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29 September 2017

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Regulation of transforming growth factor-beta activation by discrete sequences of thrombospondin 1.

3 June 2018

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Prolonged bile duct obstruction: a new experimental model for cirrhosis in the rat

3 June 2018

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Structural analysis and expression of the human thrombospondin gene promoter

3 June 2018

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Characterization of the promoter region of the human thrombospondin gene. DNA sequences within the first intron increase transcription

3 June 2018

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Expression of cytosolic and membrane associated tissue transglutaminase in rat hepatic stellate cells and its upregulation during transdifferentiation to myofibroblasts in culture

3 June 2018

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A blocking peptide for transforming growth factor-β1 activation prevents hepatic fibrosis in vivo

27 November 2018

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Prevention of rat hepatic fibrosis by the protease inhibitor, camostat mesilate, via reduced generation of active TGF-beta

27 November 2018

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Accelerated wound healing in mice with a disruption of the thrombospondin 2 gene.

27 November 2018

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Restricted localization of thrombospondin-2 protein during mouse embryogenesis: a comparison to thrombospondin-1.

27 November 2018

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Insulinlike growth factor-II/mannose 6-phosphate receptor is expressed on CCl4-exposed rat fat-storing cells and facilitates activation of latent transforming growth factor-beta in cocultures with sinusoidal endothelial cells

27 November 2018

1 reference

12 December 2020

Expression of different isoforms of TGF-beta and the latent TGF-beta binding protein (LTBP) by rat Kupffer cells

1 reference

12 December 2020

Localization of thrombospondin in hepatocellular carcinoma

1 reference

12 December 2020

Thrombospondin 1 is expressed by proliferating mesangial cells and is up-regulated by PDGF and bFGF in vivo

1 reference

12 December 2020

Angiotensin II induces thrombospondin-1 production in human mesangial cells via p38 MAPK and JNK: a mechanism for activation of latent TGF-β1

1 reference

12 December 2020

Increased expression of transforming growth factor-beta1 and thrombospondin-1 in congenital hepatic fibrosis: possible role of the hepatic stellate cell

1 reference

12 December 2020

Thrombospondin mediates migration and potentiates platelet-derived growth factor-dependent migration of calf pulmonary artery smooth muscle cells

1 reference

12 December 2020

Induction of thrombospondin messenger RNA levels occurs as an immediate primary response to platelet-derived growth factor

1 reference

12 December 2020

Sustained expression of thrombospondin-1 is associated with the development of glomerular and tubulointerstitial fibrosis in the remnant kidney model

1 reference

12 December 2020

Antagonistic Effects of TNF-α on TGF-β Signaling Through Down-Regulation of TGF-β Receptor Type II in Human Dermal Fibroblasts

1 reference

12 December 2020

Expression and matrix deposition of latent transforming growth factor beta binding proteins in normal and fibrotic rat liver and transdifferentiating hepatic stellate cells in culture

1 reference

12 December 2020

Identifiers

DOI

10.1136/GUT.2004.042911

1 reference

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1 reference

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