Dynorphin A, kappa opioid receptors and the antinociceptive efficacy of asimadoline in streptozotocin-induced diabetic rats (Q28575600)

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A pharmacological profile of the novel, peripherally-selective kappa-opioid receptor agonist, EMD 61753.

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Central and peripheral actions of the novel kappa-opioid receptor agonist, EMD 60400

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Controlled-release oxycodone for pain in diabetic neuropathy: a randomized controlled trial

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Axonal transport of opiate receptors in capsaicin-sensitive neurones

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12 December 2020

Effect of Hyperglycemia on Pain Perception and on Efficacy of Morphine Analgesia in Rats

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12 December 2020

Antinociceptive effect of U-50488H, a kappa-opioid agonist, in streptozotocin-induced diabetic mice

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12 December 2020

Extraterritorial neuropathic pain correlates with multisegmental elevation of spinal dynorphin in nerve-injured rats.

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12 December 2020

Controlled-release oxycodone relieves neuropathic pain: a randomized controlled trial in painful diabetic neuropathy

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12 December 2020

N-methyl-D-aspartate (NMDA) and opioid receptors mediate dynorphin-induced spinal cord injury: behavioral and histological studies

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12 December 2020

Gabapentin prevents hyperalgesia during the formalin test in diabetic rats

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12 December 2020

Single intrathecal injections of dynorphin A or des-Tyr-dynorphins produce long-lasting allodynia in rats: blockade by MK-801 but not naloxone

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12 December 2020

Quantitative assessment of tactile allodynia in the rat paw

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12 December 2020

Inflammation of the rat paw enhances axonal transport of opioid receptors in the sciatic nerve and increases their density in the inflamed tissue

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12 December 2020

Effects of streptozotocin-induced diabetes on prodynorphin-derived peptides in rat brain regions

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12 December 2020

Peripheral effects of the kappa-opioid agonist EMD 61753 on pain and inflammation in rats and humans.

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12 December 2020

Up-regulation of opioid gene expression in spinal cord evoked by experimental nerve injuries and inflammation

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12 December 2020

Role of blood-brain barrier P-glycoprotein in limiting brain accumulation and sedative side-effects of asimadoline, a peripherally acting analgaesic drug

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12 December 2020

Fine-structural localization of aldose reductase and ouabain-sensitive, K(+)-dependent p-nitro-phenylphosphatase in rat peripheral nerve

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12 December 2020

Increased staining of immunoreactive dynorphin cell bodies in the deafferented spinal cord of the rat.

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12 December 2020

Protection of sensory function and antihyperalgesic properties of a prosaposin-derived peptide in diabetic rats.

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12 December 2020

Evidence for a kappa-opioid receptor on pituitary astrocytes: an autoradiographic study

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12 December 2020

Antinociceptive effect of morphine, but not mu opioid receptor number, is attenuated in the spinal cord of diabetic rats

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12 December 2020

Pathway-specific patterns of the co-existence of substance P, calcitonin gene-related peptide, cholecystokinin and dynorphin in neurons of the dorsal root ganglia of the guinea-pig

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12 December 2020

Prosaposin gene expression and the efficacy of a prosaposin-derived peptide in preventing structural and functional disorders of peripheral nerve in diabetic rats

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12 December 2020

Lack of cross-tolerance between the antinociceptive effects of systemic morphine and asimadoline, a peripherally-selective kappa-opioid agonist, in CCI-neuropathic rats

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12 December 2020

Potential mechanisms of neuropathic pain in diabetes

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12 December 2020

Mechanisms of induction of persistent nociception by dynorphin.

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12 December 2020

Prostaglandin E2 release evoked by intrathecal dynorphin is dependent on spinal p38 mitogen activated protein kinase

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12 December 2020

Psychotomimesis mediated by kappa opiate receptors

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12 December 2020

Peripheral kappa-opioid modulation of the formalin response: an electrophysiological study in the rat.

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12 December 2020

Neuropathic pain activates the endogenous kappa opioid system in mouse spinal cord and induces opioid receptor tolerance

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12 December 2020

Elevated spinal cyclooxygenase and prostaglandin release during hyperalgesia in diabetic rats

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12 December 2020

Is the reduced efficacy of morphine in diabetic rats caused by alterations of opiate receptors or of morphine pharmacokinetics?

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12 December 2020

Arylacetamide kappa-opioid receptor agonists produce a tonic- and use-dependent block of tetrodotoxin-sensitive and -resistant sodium currents in colon sensory neurons

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12 December 2020

Dynorphin, a preferential ligand for kappa-opioid receptors, is present in nerve fibers and immune cells within inflamed tissue of the rat.

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12 December 2020

Dynorphin Is a Specific Endogenous Ligand of the κ Opioid Receptor

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12 December 2020

Mouse strains that lack spinal dynorphin upregulation after peripheral nerve injury do not develop neuropathic pain

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12 December 2020

Involvement of substance P in the anti-inflammatory effects of the peripherally selective kappa-opioid asimadoline and the NK1 antagonist GR205171.

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12 December 2020

Spinal pharmacology of tactile allodynia in diabetic rats

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12 December 2020

Peripheral and central antinociceptive actions of ethylketocyclazocine in the formalin test

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12 December 2020

Gabapentin and pregabalin, but not morphine and amitriptyline, block both static and dynamic components of mechanical allodynia induced by streptozocin in the rat

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12 December 2020

Spinal systems and pain processing: development of novel analgesic drugs with mechanistically defined models

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12 December 2020

A pharmacologic analysis of mechanical hyperalgesia in streptozotocin/diabetic rats

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12 December 2020

Tactile allodynia and formalin hyperalgesia in streptozotocin-diabetic rats: effects of insulin, aldose reductase inhibition and lidocaine

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12 December 2020

Effect of the peripherally selective kappa-opioid agonist, asimadoline, on adjuvant arthritis

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12 December 2020

Opioid agonists and antagonists: an evaluation of their peripheral actions in inflammation

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12 December 2020

Neuropathic pain: the paradox of dynorphin

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12 December 2020

Pronociceptive actions of dynorphin maintain chronic neuropathic pain

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12 December 2020