Exchange protein activated by cAMP (Epac) mediates cAMP-dependent but protein kinase A-insensitive modulation of vascular ATP-sensitive potassium channels (Q28581691)

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English	Exchange protein activated by cAMP (Epac) mediates cAMP-dependent but protein kinase A-insensitive modulation of vascular ATP-sensitive potassium channels	scientific journal article

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31 January 2017

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19491242%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

Exchange protein activated by cAMP (Epac) mediates cAMP-dependent but protein kinase A-insensitive modulation of vascular ATP-sensitive potassium channels (English)

2 references

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31 January 2017

Europe PubMed Central

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29 January 2020

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29 January 2020

author name string

Tomoko Kamishima

2

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31 January 2017

Europe PubMed Central

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29 January 2020

Gregor I Purves

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29 January 2020

Lowri M Davies

3

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29 January 2020

John M Quayle

4

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29 January 2020

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1 July 2009

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29 January 2020

Journal of Physiology

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31 January 2017

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19491242%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

587

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PubMed publication ID

31 January 2017

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19491242%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

Pt 14

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31 January 2017

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19491242%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

3639-3650

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PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19491242%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

Role of the cAMP sensor Epac as a determinant of KATP channel ATP sensitivity in human pancreatic beta-cells and rat INS-1 cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2742287

17 March 2017

Exchange protein activated by cAMP (Epac) mediates cAMP activation of p38 MAPK and modulation of Ca2+-dependent K+ channels in cerebellar neurons

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2742287

17 March 2017

Cell physiology of cAMP sensor Epac

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2742287

17 March 2017

cAMP sensor Epac as a determinant of ATP-sensitive potassium channel activity in human pancreatic beta cells and rat INS-1 cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2742287

17 March 2017

KATP channels as molecular sensors of cellular metabolism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2742287

17 March 2017

The protein kinase A anchoring protein mAKAP coordinates two integrated cAMP effector pathways.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2742287

17 March 2017

Caveolae localize protein kinase A signaling to arterial ATP-sensitive potassium channels

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2742287

17 March 2017

Direct interaction between the actin-binding protein filamin-A and the inwardly rectifying potassium channel, Kir2.1

1 reference

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17 March 2017

Epac-selective cAMP analog 8-pCPT-2'-O-Me-cAMP as a stimulus for Ca2+-induced Ca2+ release and exocytosis in pancreatic beta-cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2742287

17 March 2017

Structure and regulation of the cAMP-binding domains of Epac2

1 reference

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17 March 2017

Glucagon-like peptide-1 mobilizes intracellular Ca2+ and stimulates mitochondrial ATP synthesis in pancreatic MIN6 beta-cells

1 reference

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17 March 2017

Episodic coronary artery vasospasm and hypertension develop in the absence of Sur2 K(ATP) channels

1 reference

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17 March 2017

Mouse model of Prinzmetal angina by disruption of the inward rectifier Kir6.1

1 reference

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A new phospholipase-C-calcium signalling pathway mediated by cyclic AMP and a Rap GTPase

1 reference

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17 March 2017

Evidence for involvement of A-kinase anchoring protein in activation of rat arterial K(ATP) channels by protein kinase A

1 reference

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17 March 2017

cAMP-regulated guanine nucleotide exchange factor II (Epac2) mediates Ca2+-induced Ca2+ release in INS-1 pancreatic beta-cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2742287

17 March 2017

Angiotensin II inhibits rat arterial KATP channels by inhibiting steady-state protein kinase A activity and activating protein kinase Ce

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2742287

17 March 2017

cAMP-GEFII is a direct target of cAMP in regulated exocytosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2742287

17 March 2017

Mechanism of regulation of the Epac family of cAMP-dependent RapGEFs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2742287

17 March 2017

A family of cAMP-binding proteins that directly activate Rap1

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2742287

17 March 2017

Epac is a Rap1 guanine-nucleotide-exchange factor directly activated by cyclic AMP

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2742287

17 March 2017

Essential role of Epac2/Rap1 signaling in regulation of insulin granule dynamics by cAMP.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2742287

29 September 2017

PKA phosphorylation of SUR2B subunit underscores vascular KATP channel activation by beta-adrenergic receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2742287

29 September 2017

Hydrolysis products of cAMP analogs cause transformation of Trypanosoma brucei from slender to stumpy-like forms.

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29 September 2017

Epac proteins: multi-purpose cAMP targets

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2742287

29 September 2017

K(ATP) channels and insulin secretion: a key role in health and disease

1 reference

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Dopamine regulation of amiloride-sensitive sodium channels in lung cells.

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29 September 2017

PKA-dependent and PKA-independent pathways for cAMP-regulated exocytosis

1 reference

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29 September 2017

Roles of KATP channels as metabolic sensors in acute metabolic changes

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29 September 2017

Detecting cAMP-induced Epac activation by fluorescence resonance energy transfer: Epac as a novel cAMP indicator

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29 September 2017

Multisite phosphorylation mechanism for protein kinase A activation of the smooth muscle ATP-sensitive K+ channel

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29 September 2017

cAMP analog mapping of Epac1 and cAMP kinase. Discriminating analogs demonstrate that Epac and cAMP kinase act synergistically to promote PC-12 cell neurite extension

1 reference

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29 September 2017

Cyclic AMP induces integrin-mediated cell adhesion through Epac and Rap1 upon stimulation of the beta 2-adrenergic receptor

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29 September 2017

A novel Epac-specific cAMP analogue demonstrates independent regulation of Rap1 and ERK.

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29 September 2017

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29 September 2017

Adenosine activates ATP-sensitive potassium channels in arterial myocytes via A2 receptors and cAMP-dependent protein kinase

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29 September 2017

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3 June 2018

ATP-sensitive K+ channels in pancreatic, cardiac, and vascular smooth muscle cells.

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3 June 2018

Potassium channels in the vasculature

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3 June 2018

ATP-sensitive and inwardly rectifying potassium channels in smooth muscle

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3 June 2018

ATP-sensitive potassium channel is essential to maintain basal coronary vascular tone in vivo

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Cyclic nucleotide research -- still expanding after half a century

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cAMP-binding protein Epac induces cardiomyocyte hypertrophy.

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Exposure to cAMP and beta-adrenergic stimulation recruits Ca(V)3 T-type channels in rat chromaffin cells through Epac cAMP-receptor proteins

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21 January 2018

cAMP-dependent protein kinase phosphorylation produces interdomain movement in SUR2B leading to activation of the vascular KATP channel

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https://api.crossref.org/works/10.1113%2FJPHYSIOL.2009.173534

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Calcium modulation of vascular smooth muscle ATP-sensitive K(+) channels: role of protein phosphatase-2B

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12 December 2020

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Mapping adenosine cyclic 3',5'-phosphate binding sites on type I and type II adenosine cyclic 3',5'-phosphate dependent protein kinases using ribose ring and cyclic phosphate ring analogs of adenosine cyclic 3',5'-phosphate

1 reference

https://pubmed.ncbi.nlm.nih.gov/19491242

12 December 2020

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ATP-sensitive K+ channel activation by calcitonin gene-related peptide and protein kinase A in pig coronary arterial smooth muscle

1 reference

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Glucagon activates Ca2+ and Cl- channels in rat hepatocytes

1 reference

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12 December 2020

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Epac1 and cAMP-dependent Protein Kinase Holoenzyme Have Similar cAMP Affinity, but Their cAMP Domains Have Distinct Structural Features and Cyclic Nucleotide Recognition

1 reference

https://pubmed.ncbi.nlm.nih.gov/19491242

12 December 2020

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Epac-mediated Ca(2+) mobilization and exocytosis in inner medullary collecting duct

1 reference

https://pubmed.ncbi.nlm.nih.gov/19491242

12 December 2020

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inferred from PubMed ID database lookup

Calcitonin gene-related peptide activated ATP-sensitive K+ currents in rabbit arterial smooth muscle via protein kinase A

1 reference

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Activation of ATP-sensitive K+ channels by cyclic AMP-dependent protein kinase in cultured smooth muscle cells of porcine coronary artery

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1113/JPHYSIOL.2009.173534

2 references

PubMed publication ID

31 January 2017

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19491242%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

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0 references

PubMed publication ID

2 references

PubMed publication ID

31 January 2017

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19491242%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

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