Essential role of Epac2/Rap1 signaling in regulation of insulin granule dynamics by cAMP. (Q34718424)

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28 December 2019

title

Essential role of Epac2/Rap1 signaling in regulation of insulin granule dynamics by cAMP (English)

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28 December 2019

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10

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28 December 2019

author name string

Tadao Shibasaki

1

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28 December 2019

Harumi Takahashi

2

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28 December 2019

Takashi Miki

3

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28 December 2019

Yasuhiro Sunaga

4

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28 December 2019

Kimio Matsumura

5

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28 December 2019

Mami Yamanaka

6

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28 December 2019

Changliang Zhang

7

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28 December 2019

Atsuko Tamamoto

8

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28 December 2019

Takaya Satoh

9

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28 December 2019

Susumu Seino

11

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28 December 2019

language of work or name

English

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publication date

26 November 2007

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Proceedings of the National Academy of Sciences of the United States of America

28 December 2019

published in

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28 December 2019

volume

104

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28 December 2019

issue

49

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28 December 2019

page(s)

19333-19338

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Rap1: a key regulator in cell-cell junction formation

28 December 2019

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1 reference

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7 July 2018

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7 July 2018

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PKA-dependent and PKA-independent pathways for cAMP-regulated exocytosis

7 July 2018

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Rap1 promotes cell spreading by localizing Rac guanine nucleotide exchange factors

7 July 2018

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Evidence for the involvement of cAMP-GEF (Epac) pathway in amylase release from the rat parotid gland

7 July 2018

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Role of incretin hormones in the regulation of insulin secretion in diabetic and nondiabetic humans

7 July 2018

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The synaptic vesicle cycle

7 July 2018

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Insulin granule dynamics in pancreatic beta cells

7 July 2018

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Secretory granule exocytosis

7 July 2018

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SUR1 regulates PKA-independent cAMP-induced granule priming in mouse pancreatic B-cells

7 July 2018

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Gastric inhibitory polypeptide: the neglected incretin revisited

7 July 2018

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Nutrient-secretion coupling in the pancreatic islet beta-cell: recent advances

7 July 2018

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A variant of yellow fluorescent protein with fast and efficient maturation for cell-biological applications

7 July 2018

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Imaging exocytosis of single insulin secretory granules with evanescent wave microscopy: distinct behavior of granule motion in biphasic insulin release

7 July 2018

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cAMP-regulated guanine nucleotide exchange factor II (Epac2) mediates Ca2+-induced Ca2+ release in INS-1 pancreatic beta-cells

7 July 2018

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Critical role of cAMP-GEFII--Rim2 complex in incretin-potentiated insulin secretion

7 July 2018

1 reference

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Mitochondrial signals in glucose-stimulated insulin secretion in the beta cell

7 July 2018

1 reference

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cAMP-GEFII is a direct target of cAMP in regulated exocytosis

7 July 2018

1 reference

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Synergism of protein kinase A, protein kinase C, and myosin light-chain kinase in the secretory cascade of the pancreatic beta-cell

7 July 2018

1 reference

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Mechanism of regulation of the Epac family of cAMP-dependent RapGEFs

7 July 2018

1 reference

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RA-GEF, a novel Rap1A guanine nucleotide exchange factor containing a Ras/Rap1A-associating domain, is conserved between nematode and humans

7 July 2018

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Glucagon-like peptide 1 elevates cytosolic calcium in pancreatic beta-cells independently of protein kinase A.

7 July 2018

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A family of cAMP-binding proteins that directly activate Rap1

7 July 2018

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Establishment of a pancreatic beta cell line that retains glucose-inducible insulin secretion: special reference to expression of glucose transporter isoforms

7 July 2018

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cAMP increases Ca2+-dependent exocytosis through both PKA and Epac2 in mouse melanotrophs from pituitary tissue slices

7 July 2018

1 reference

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A cAMP and Ca2+ coincidence detector in support of Ca2+-induced Ca2+ release in mouse pancreatic beta cells

26 October 2018

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The structural organization of the readily releasable pool of synaptic vesicles

26 October 2018

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Direct modulation of synaptic vesicle priming by GABA(B) receptor activation at a glutamatergic synapse

26 October 2018

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Effect of 6-week course of glucagon-like peptide 1 on glycaemic control, insulin sensitivity, and beta-cell function in type 2 diabetes: a parallel-group study

26 October 2018

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Regulation of exocytosis in neuroendocrine cells: spatial organization of channels and vesicles, stimulus-secretion coupling, calcium buffers and modulation

26 October 2018

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12 December 2020

Compartments of cyclic AMP and protein kinase in mammalian cardiomyocytes

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12 December 2020

Calcium-independent potentiation of insulin release by cyclic AMP in single β-cells

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12 December 2020

Protein kinase A-dependent and -independent stimulation of exocytosis by cAMP in mouse pancreatic B-cells

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12 December 2020

Identifiers

DOI

10.1073/PNAS.0707054104

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18040047%20AND%20SRC:MED&resulttype=core&format=json

28 December 2019

0 references

1 reference

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28 December 2019

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