Activation of p21CIP1/WAF1 gene expression and inhibition of cell proliferation by overexpression of hepatocyte nuclear factor-4alpha (Q28583194)

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31 January 2017

Seiro Satohisa

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31 January 2017

Naoyuki Sakai

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31 January 2017

Hiroko Noguchi

5

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31 January 2017

Makoto Osanai

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31 January 2017

Norimasa Sawada

Experimental Cell Research

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31 January 2017

language of work or name

English

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publication date

1 January 2005

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31 January 2017

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31 January 2017

302

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31 January 2017

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31 January 2017

11–21

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31 January 2017

Liver-enriched transcription factor HNF-4 is a novel member of the steroid hormone receptor superfamily

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The maturity-onset diabetes of the young (MODY1) transcription factor HNF4alpha regulates expression of genes required for glucose transport and metabolism

7 January 2021

1 reference

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Hepatocyte nuclear factor 4alpha (nuclear receptor 2A1) is essential for maintenance of hepatic gene expression and lipid homeostasis

7 January 2021

1 reference

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A developmental transition in definitive erythropoiesis: erythropoietin expression is sequentially regulated by retinoic acid receptors and HNF4

7 January 2021

1 reference

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Defective ureagenesis in mice carrying a liver-specific disruption of hepatocyte nuclear factor 4alpha (HNF4alpha ). HNF4alpha regulates ornithine transcarbamylase in vivo

7 January 2021

1 reference

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The orphan nuclear receptor HNF4alpha determines PXR- and CAR-mediated xenobiotic induction of CYP3A4

7 January 2021

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HNF4: A central regulator of hepatocyte differentiation and function

7 January 2021

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Fatty acyl-CoA thioesters are ligands of hepatic nuclear factor-4α

7 January 2021

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Ligand specificity and conformational dependence of the hepatic nuclear factor-4alpha (HNF-4alpha ).

7 January 2021

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Crystal structure of the HNF4 alpha ligand binding domain in complex with endogenous fatty acid ligand

7 January 2021

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Competitive cofactor recruitment by orphan receptor hepatocyte nuclear factor 4alpha1: modulation by the F domain

7 January 2021

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Hepatocyte nuclear factor 4 is a transcription factor that constitutively binds fatty acids

7 January 2021

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Desperately seeking...something

7 January 2021

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Expression of transcription factor HNF-4 in the extraembryonic endoderm, gut, and nephrogenic tissue of the developing mouse embryo: HNF-4 is a marker for primary endoderm in the implanting blastocyst

7 January 2021

1 reference

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Disruption of the HNF-4 gene, expressed in visceral endoderm, leads to cell death in embryonic ectoderm and impaired gastrulation of mouse embryos

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YEXCR.2004.08.014

Liver-enriched transcription factors and hepatocyte differentiation.

7 January 2021

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Hepatocyte nuclear factor 4 expression overcomes repression of the hepatic phenotype in dedifferentiated hepatoma cells

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YEXCR.2004.08.014

Hepatocyte nuclear factor 4 provokes expression of epithelial marker genes, acting as a morphogen in dedifferentiated hepatoma cells

7 January 2021

1 reference

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Hepatocyte nuclear factor 4alpha controls the development of a hepatic epithelium and liver morphogenesis

7 January 2021

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Four-dimensional control of the cell cycle

7 January 2021

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Evolving ideas about cyclins

7 January 2021

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CDK inhibitors: positive and negative regulators of G1-phase progression

7 January 2021

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Regulation of G(1) cyclin-dependent kinases in the mammalian cell cycle

7 January 2021

1 reference

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Mouse teratocarcinoma cells: prospects for the study of embryogenesis and neoplasia

7 January 2021

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Differentiation and proliferation in mouse embryonal carcinoma cells

7 January 2021

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Specific and redundant functions of retinoid X Receptor/Retinoic acid receptor heterodimers in differentiation, proliferation, and apoptosis of F9 embryonal carcinoma cells

7 January 2021

1 reference

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Distinct roles of the co-activators p300 and CBP in retinoic-acid-induced F9-cell differentiation

7 January 2021

1 reference

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The targeted disruption of both alleles of RARbeta(2) in F9 cells results in the loss of retinoic acid-associated growth arrest.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2004.08.014

F9 embryonal carcinoma cells engineered for tamoxifen-dependent Cre-mediated site-directed mutagenesis and doxycycline-inducible gene expression

7 January 2021

1 reference

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Retinoid X receptor alpha and retinoic acid receptor gamma mediate expression of genes encoding tight-junction proteins and barrier function in F9 cells during visceral endodermal differentiation

7 January 2021

1 reference

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Hepatocyte nuclear factor (HNF)-4α triggers formation of functional tight junctions and establishment of polarized epithelial morphology in F9 embryonal carcinoma cells

7 January 2021

1 reference

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Nonsteroid nuclear receptors: what are genetic studies telling us about their role in real life?

7 January 2021

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Retinoids in embryonal development

7 January 2021

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Physiological and retinoid-induced proliferations of epidermis basal keratinocytes are differently controlled

7 January 2021

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Hepatocyte nuclear factor (HNF)-4alpha induces expression of endothelial Fas ligand (FasL) to prevent cancer cell transmigration: a novel defense mechanism of endothelium against cancer metastasis

7 January 2021

1 reference

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Tight control of gene expression in mammalian cells by tetracycline-responsive promoters

7 January 2021

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Site- and time-specific gene targeting in the mouse

7 January 2021

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Distinct retinoid X receptor-retinoic acid receptor heterodimers are differentially involved in the control of expression of retinoid target genes in F9 embryonal carcinoma cells

7 January 2021

1 reference

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Thr203 of claudin-1, a putative phosphorylation site for MAP kinase, is required to promote the barrier function of tight junctions

7 January 2021

1 reference

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Cyclic AMP induces phosphorylation of claudin-5 immunoprecipitates and expression of claudin-5 gene in blood-brain-barrier endothelial cells via protein kinase A-dependent and -independent pathways.

7 January 2021

1 reference

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Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

7 January 2021

1 reference

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Transcriptional activation of the human p21(WAF1/CIP1) gene by retinoic acid receptor. Correlation with retinoid induction of U937 cell differentiation

7 January 2021

1 reference

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Progression of HCC in mice is associated with a downregulation in the expression of hepatocyte nuclear factors

7 January 2021

1 reference

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The p21(Cip1) and p27(Kip1) CDK 'inhibitors' are essential activators of cyclin D-dependent kinases in murine fibroblasts

7 January 2021

1 reference

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The origin of CDK regulation

7 January 2021

1 reference

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Analysis of gene expression profile induced by hepatocyte nuclear factor 4alpha in hepatoma cells using an oligonucleotide microarray

7 January 2021

1 reference

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Transcriptional activation of the Cdk inhibitor p21 by vitamin D3 leads to the induced differentiation of the myelomonocytic cell line U937.

7 January 2021

1 reference

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Androgen regulation of the cyclin-dependent kinase inhibitor p21 gene through an androgen response element in the proximal promoter

7 January 2021

1 reference

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Expanding the TRANSFAC database towards an expert system of regulatory molecular mechanisms

7 January 2021

1 reference

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Progesterone regulates transcription of the p21(WAF1) cyclin- dependent kinase inhibitor gene through Sp1 and CBP/p300.

7 January 2021

1 reference

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Androgen induction of cyclin-dependent kinase inhibitor p21 gene: role of androgen receptor and transcription factor Sp1 complex

7 January 2021

1 reference

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Correlation of terminal cell cycle arrest of skeletal muscle with induction of p21 by MyoD.

7 January 2021

1 reference

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Involvement of the cell-cycle inhibitor Cip1/WAF1 and the E1A-associated p300 protein in terminal differentiation.

7 January 2021

1 reference

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p53-independent expression of p21Cip1 in muscle and other terminally differentiating cells

7 January 2021

1 reference

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Transcriptional Regulation of the p21(WAF1/CIP1)Gene

7 January 2021

1 reference

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The ZO-1-associated Y-box factor ZONAB regulates epithelial cell proliferation and cell density

7 January 2021

1 reference

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The tight junction protein ZO-2 associates with Jun, Fos and C/EBP transcription factors in epithelial cells.

7 January 2021

1 reference

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AP-1 as a regulator of cell life and death

7 January 2021

1 reference

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