Novel liver-specific TORC2 siRNA corrects hyperglycemia in rodent models of type 2 diabetes (Q28583617)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19706791%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

title

Novel liver-specific TORC2 siRNA corrects hyperglycemia in rodent models of type 2 diabetes (English)

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19706791%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

0 references

1 reference

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19706791%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

Pingping Li

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19706791%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

author name string

Maziyar Saberi

1

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19706791%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

David Bjelica

2

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19706791%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

Takeshi Imamura

4

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19706791%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

Gautam Bandyopadhyay

5

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19706791%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

Vasant Jadhar

7

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19706791%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

Chandra Vargeese

8

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19706791%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

Weimin Wang

9

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19706791%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

Keith Bowman

10

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19706791%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

Ye Zhang

11

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19706791%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

Barry Polisky

12

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19706791%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

Jerrold M Olefsky

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19706791%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

publication date

25 August 2009

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19706791%20AND%20SRC:MED&resulttype=core&format=json

American Journal of Physiology - Endocrinology and Metabolism

6 February 2020

published in

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19706791%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

volume

297

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19706791%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

issue

5

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19706791%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

page(s)

E1137-46

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19706791%20AND%20SRC:MED&resulttype=core&format=json

Small molecule activators of SIRT1 as therapeutics for the treatment of type 2 diabetes

6 February 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2781351

The CREB coactivator TORC2 is a key regulator of fasting glucose metabolism

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2781351

Prevention of hepatic steatosis and hepatic insulin resistance in mitochondrial acyl-CoA:glycerol-sn-3-phosphate acyltransferase 1 knockout mice

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2781351

Muscle-specific Pparg deletion causes insulin resistance

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2781351

Insulin-induced GLUT4 translocation involves protein kinase C-lambda-mediated functional coupling between Rab4 and the motor protein kinesin

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2781351

CREB regulates hepatic gluconeogenesis through the coactivator PGC-1

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2781351

Nonviral delivery of synthetic siRNAs in vivo

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2781351

Glucolipotoxicity: fuel excess and beta-cell dysfunction.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2781351

Insulin modulates gluconeogenesis by inhibition of the coactivator TORC2.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2781351

Hepatic overexpression of glycerol-sn-3-phosphate acyltransferase 1 in rats causes insulin resistance

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2781351

Therapeutic potential of RNAi in metabolic diseases.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2781351

Adipocyte-derived hormones, cytokines, and mediators

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2781351

Dual role of the coactivator TORC2 in modulating hepatic glucose output and insulin signaling.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2781351

Potent and persistent in vivo anti-HBV activity of chemically modified siRNAs

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2781351

Nutrient-induced insulin resistance in human skeletal muscle

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2781351

Hepatic steatosis: a mediator of the metabolic syndrome. Lessons from animal models

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2781351

Synthesis, deprotection, analysis and purification of RNA and ribozymes

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2781351

Receptor and postreceptor defects contribute to the insulin resistance in noninsulin-dependent diabetes mellitus

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2781351

Hepatic glucose production in insulin-resistant states.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2781351

Quantitation of hepatic glycogenolysis and gluconeogenesis in fasting humans with 13C NMR.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2781351

Increased rate of gluconeogenesis in type II diabetes mellitus. A 13C nuclear magnetic resonance study

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2781351

Increased malonyl-CoA levels in muscle from obese and type 2 diabetic subjects lead to decreased fatty acid oxidation and increased lipogenesis; thiazolidinedione treatment reverses these defects

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2781351

Glucose production, recycling, and gluconeogenesis in normals and diabetics: a mass isotopomer [U-13C]glucose study

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2781351

The Diabetic Zucker Fatty Rat

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2781351

Predominant role of gluconeogenesis in increased hepatic glucose production in NIDDM.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2781351

Contribution of abnormal muscle and liver glucose metabolism to postprandial hyperglycemia in NIDDM.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2781351

Hepatic glucose sensing via the CREB coactivator CRTC2.

3 June 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00158.2009

Significant correlations between severe fatty liver and risk factors for metabolic syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00158.2009

PGC-1 promotes insulin resistance in liver through PPAR-alpha-dependent induction of TRB-3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00158.2009

Intramyocellular lipid concentrations are correlated with insulin sensitivity in humans: a 1H NMR spectroscopy study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00158.2009

Insulin action in non-insulin-dependent diabetes mellitus: the relationship between hepatic and extrahepatic insulin resistance and obesity

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19706791

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

The estimation of glycogen with the anthrone reagent

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19706791

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Influences of glucose loading and of injected insulin on hepatic glucose output

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19706791

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1152/AJPENDO.00158.2009

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19706791%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19706791%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

2 references