Genetic rescue of Cdk4 null mice restores pancreatic beta-cell proliferation but not homeostatic cell number (Q28584893)

GOA release 2020-03-11

Rocío Sotillo

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Mark Magnuson

object named as

Mark A. Magnuson

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Marcos Malumbres

object named as

Marcos Malumbres

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author name string

Javier Martín

1

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31 January 2017

Sarah L. Hunt

2

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31 January 2017

Pierre Dubus

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31 January 2017

Fanny Néhmé-Pélluard

5

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31 January 2017

Albert F. Parlow

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31 January 2017

Sagrario Ortega

9

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31 January 2017

Mariano Barbacid

Islet growth and development in the adult

10

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31 January 2017

language of work or name

English

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publication date

14 August 2003

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31 January 2017

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31 January 2017

22

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31 January 2017

34

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31 January 2017

5261–5269

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31 January 2017

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206506

Life and death of the pancreatic beta cells

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The regulation of E2F by pRB-family proteins

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Mice lacking cyclin D1 are small and show defects in eye and mammary gland development.

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Dynamics of beta-cell mass in the growing rat pancreas. Estimation with a simple mathematical model.

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Functional collaboration between different cyclin-dependent kinase inhibitors suppresses tumor growth with distinct tissue specificity

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Analysis of the Cre-mediated recombination driven by rat insulin promoter in embryonic and adult mouse pancreas

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Intercellular signals regulating pancreas development and function

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Tissue-specific knockout of the insulin receptor in pancreatic beta cells creates an insulin secretory defect similar to that in type 2 diabetes.

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1 reference

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Limited overlapping roles of P15(INK4b) and P18(INK4c) cell cycle inhibitors in proliferation and tumorigenesis

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1 reference

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Functional inactivation of the retinoblastoma protein requires sequential modification by at least two distinct cyclin-cdk complexes

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To cycle or not to cycle: a critical decision in cancer.

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Drosophila Cdk4 is required for normal growth and is dispensable for cell cycle progression

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Linear correlation between beta-cell mass and body weight throughout the lifespan in Lewis rats: role of beta-cell hyperplasia and hypertrophy

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Intact follicular maturation and defective luteal function in mice deficient for cyclin- dependent kinase-4.

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1 reference

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Principles of CDK regulation

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1 reference

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G1 events and regulation of cell proliferation

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1 reference

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Mechanisms of cyclin-dependent kinase regulation: structures of Cdks, their cyclin activators, and Cip and INK4 inhibitors

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Dual roles for glucokinase in glucose homeostasis as determined by liver and pancreatic beta cell-specific gene knock-outs using Cre recombinase

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Loss of Cdk4 expression causes insulin-deficient diabetes and Cdk4 activation results in beta-islet cell hyperplasia

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CDK inhibitors: positive and negative regulators of G1-phase progression

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Cyclin D1 provides a link between development and oncogenesis in the retina and breast.

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Wide spectrum of tumors in knock-in mice carrying a Cdk4 protein insensitive to INK4 inhibitors.

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Invasive melanoma in Cdk4-targeted mice

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Targeted disruption of CDK4 delays cell cycle entry with enhanced p27(Kip1) activity

21 January 2018

1 reference

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The retinoblastoma protein and cell cycle control

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A p16INK4a-insensitive CDK4 mutant targeted by cytolytic T lymphocytes in a human melanoma

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1 reference

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Germline mutations in the p16INK4a binding domain of CDK4 in familial melanoma

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Pituitary Hypoplasia and Lactotroph Dysfunction in Mice Deficient for Cyclin-Dependent Kinase-4

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1 reference

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inferred from DOI database lookup

7 January 2021

based on heuristic

Treatment of periorbital wrinkles. A comparison of the SilkTouch carbon dioxide laser with a medium-depth chemical peel

1 reference

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inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/SJ.ONC.1206506

1 reference

Consolidated OpenCitations Corpus – April 2017

Dimensions Publication ID

2448257

1014548918

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2448257

1 reference

Consolidated OpenCitations Corpus – April 2017

Consolidated OpenCitations Corpus – April 2017

1 reference