Aire controls the differentiation program of thymic epithelial cells in the medulla for the establishment of self-tolerance (Q28585306)

GOA release 2020-03-11

author name string

Masashi Yano

1

1 reference

31 January 2017

Noriyuki Kuroda

2

1 reference

31 January 2017

Hongwei Han

3

1 reference

31 January 2017

Makiko Meguro-Horike

4

1 reference

31 January 2017

Yumiko Nishikawa

5

1 reference

31 January 2017

Hiroshi Kiyonari

6

1 reference

31 January 2017

Kentaro Maemura

7

1 reference

31 January 2017

Yuchio Yanagawa

8

1 reference

31 January 2017

Kunihiko Obata

9

1 reference

31 January 2017

Satoru Takahashi

10

1 reference

31 January 2017

Tomokatsu Ikawa

11

1 reference

31 January 2017

Rumi Satoh

12

1 reference

31 January 2017

Hiroshi Kawamoto

13

1 reference

31 January 2017

Yasuhiro Mouri

14

1 reference

31 January 2017

Mitsuru Matsumoto

Journal of Experimental Medicine

15

1 reference

31 January 2017

language of work or name

English

0 references

publication date

24 November 2008

1 reference

31 January 2017

1 reference

31 January 2017

205

1 reference

31 January 2017

12

1 reference

31 January 2017

2827–2838

1 reference

31 January 2017

p63 Is essential for the proliferative potential of stem cells in stratified epithelia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2585853

Central tolerance: learning self-control in the thymus

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2585853

Projection of an immunological self shadow within the thymus by the aire protein

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2585853

Localization of the APECED protein in distinct nuclear structures

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2585853

Gene defect behind APECED: a new clue to autoimmunity

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2585853

Proliferative arrest and rapid turnover of thymic epithelial cells expressing Aire

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2585853

Transcriptional regulation in thymic epithelial cells for the establishment of self tolerance

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2585853

Spontaneous autoimmunity prevented by thymic expression of a single self-antigen

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2585853

MafB is essential for renal development and F4/80 expression in macrophages

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2585853

Alteration of intra-pancreatic target-organ specificity by abrogation of Aire in NOD mice

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2585853

A central role for central tolerance

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2585853

Contrasting models of promiscuous gene expression by thymic epithelium

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2585853

Promiscuous gene expression in thymic epithelial cells is regulated at multiple levels

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2585853

ang is a novel gene expressed in early neuroectoderm, but its null mutant exhibits no obvious phenotype

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2585853

Gene dosage--limiting role of Aire in thymic expression, clonal deletion, and organ-specific autoimmunity.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2585853

Autoimmune regulator: from loss of function to autoimmunity.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2585853

Tolerance and autoimmunity

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2585853

Epidermal differentiation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2585853

RANK signals from CD4(+)3(-) inducer cells regulate development of Aire-expressing epithelial cells in the thymic medulla

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2585853

Subcellular expression of autoimmune regulator is organized in a spatiotemporal manner

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2585853

An efficient gene-trap method using poly A trap vectors and characterization of gene-trap events

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2585853

A novel ES cell line, TT2, with high germline-differentiating potency

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2585853

Autoimmune regulator is expressed in the cells regulating immune tolerance in thymus medulla.

3 June 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20080046

Promiscuous gene expression in medullary thymic epithelial cells mirrors the peripheral self.

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20080046

The cellular mechanism of Aire control of T cell tolerance.

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20080046

Features of medullary thymic epithelium implicate postnatal development in maintaining epithelial heterogeneity and tissue-restricted antigen expression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20080046

Aire-dependent alterations in medullary thymic epithelium indicate a role for Aire in thymic epithelial differentiation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20080046

Corticosteroids regulate epithelial cell differentiation and Hassall body formation in the human thymus

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20080046

Antigen-presenting cells expressing glutamate decarboxylase 67 were identified as epithelial cells in glutamate decarboxylase 67-GFP knock-in mouse thymus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20080046

Medullary thymic epithelial cells expressing Aire represent a unique lineage derived from cells expressing claudin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20080046

Green fluorescent protein expression and colocalization with calretinin, parvalbumin, and somatostatin in the GAD67-GFP knock-in mouse.

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20080046

Simultaneous detection of EGFP and cell surface markers by fluorescence microscopy in lymphoid tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20080046

NF-kappa B-inducing kinase establishes self-tolerance in a thymic stroma-dependent manner.

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20080046

Defective TCR expression in transgenic mice constructed using cDNA-based α- and β-chain genes under the control of heterologous regulatory elements

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20080046

Characterization of human thymic epithelial cell surface antigens: phenotypic similarity of thymic epithelial cells to epidermal keratinocytes

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19015306

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Development of autoimmunity against transcriptionally unrepressed target antigen in the thymus of Aire-deficient mice

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19015306

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

A unified theory of central tolerance in the thymus

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19015306

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1084/JEM.20080046

1 reference

1957953

1957953

1 reference

1 reference

1 reference