ABIN-2 is required for optimal activation of Erk MAP kinase in innate immune responses (Q28585458)

GOA release 2020-03-11

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Anne O'Garra

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Victor Tybulewicz

object named as

Victor Tybulewicz

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author name string

Stamatia Papoutsopoulou

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31 January 2017

Antony Symons

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31 January 2017

Tharsana Tharmalingham

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31 January 2017

Monica P. Belich

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31 January 2017

Frank Kaiser

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31 January 2017

Dimitris Kioussis

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31 January 2017

Steven C. Ley

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31 January 2017

language of work or name

English

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publication date

1 June 2006

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31 January 2017

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31 January 2017

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31 January 2017

606–615

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31 January 2017

6

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31 January 2017

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Tumor necrosis factor signaling.

21 January 2018

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Phosphorylation meets ubiquitination: the control of NF-[kappa]B activity

21 January 2018

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Functions of NF-kappaB1 and NF-kappaB2 in immune cell biology

21 January 2018

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A20 and A20-binding proteins as cellular inhibitors of nuclear factor-kappa B-dependent gene expression and apoptosis

21 January 2018

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The ubiquitin-modifying enzyme A20 is required for termination of Toll-like receptor responses

21 January 2018

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Failure to regulate TNF-induced NF-kappaB and cell death responses in A20-deficient mice

21 January 2018

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Identification of a novel A20-binding inhibitor of nuclear factor-kappa B activation termed ABIN-2

21 January 2018

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The antiinflammatory endothelial tyrosine kinase Tie2 interacts with a novel nuclear factor-kappaB inhibitor ABIN-2.

21 January 2018

1 reference

The novel functions of ubiquitination in signaling

21 January 2018

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De-ubiquitination and ubiquitin ligase domains of A20 downregulate NF-kappaB signalling

21 January 2018

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ABIN-2 forms a ternary complex with TPL-2 and NF-kappa B1 p105 and is essential for TPL-2 protein stability

21 January 2018

1 reference

Tumor progression locus 2 (Tpl-2) encodes a protein kinase involved in the progression of rodent T-cell lymphomas and in T-cell activation

21 January 2018

1 reference

Structure and transforming potential of the human cot oncogene encoding a putative protein kinase

21 January 2018

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TNF-alpha induction by LPS is regulated posttranscriptionally via a Tpl2/ERK-dependent pathway

21 January 2018

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Tpl2 transduces CD40 and TNF signals that activate ERK and regulates IgE induction by CD40.

21 January 2018

1 reference

Protamine-Cre recombinase transgenes efficiently recombine target sequences in the male germ line of mice, but not in embryonic stem cells

21 January 2018

1 reference

Shaping the nuclear action of NF-kappaB

21 January 2018

1 reference

NF-kappa B controls expression of inhibitor I kappa B alpha: evidence for an inducible autoregulatory pathway

21 January 2018

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Function and activation of NF-kappa B in the immune system

21 January 2018

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The IkappaB kinase complex and NF-kappaB act as master regulators of lipopolysaccharide-induced gene expression and control subordinate activation of AP-1.

21 January 2018

1 reference

NF-kappaB regulation in the immune system

21 January 2018

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A serine/threonine kinase, Cot/Tpl2, modulates bacterial DNA-induced IL-12 production and Th cell differentiation.

21 January 2018

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TPL-2 kinase regulates the proteolysis of the NF-kappaB-inhibitory protein NF-kappaB1 p105

21 January 2018

1 reference

Lipopolysaccharide-mediated reactive oxygen species and signal transduction in the regulation of interleukin-1 gene expression

21 January 2018

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Induction of COX-2 by LPS in macrophages is regulated by Tpl2-dependent CREB activation signals.

21 January 2018

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NF-kappaB1/p105 regulates lipopolysaccharide-stimulated MAP kinase signaling by governing the stability and function of the Tpl2 kinase

21 January 2018

1 reference

Lipopolysaccharide activation of the MEK-ERK1/2 pathway in human monocytic cells mediates tissue factor and tumor necrosis factor alpha expression by inducing Elk-1 phosphorylation and Egr-1 expression

21 January 2018

1 reference

Structure-function analysis of the A20-binding inhibitor of NF-kappa B activation, ABIN-1

21 January 2018

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Recruitment of the IKK signalosome to the p55 TNF receptor: RIP and A20 bind to NEMO (IKKgamma) upon receptor stimulation

21 January 2018

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The zinc finger protein A20 inhibits TNF-induced NF-kappaB-dependent gene expression by interfering with an RIP- or TRAF2-mediated transactivation signal and directly binds to a novel NF-kappaB-inhibiting protein ABIN

21 January 2018

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NF-kappaB1 p105 negatively regulates TPL-2 MEK kinase activity

21 January 2018

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A physical and functional map of the human TNF-alpha/NF-kappa B signal transduction pathway

21 January 2018

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Lipopolysaccharide activation of the TPL-2/MEK/extracellular signal-regulated kinase mitogen-activated protein kinase cascade is regulated by IkappaB kinase-induced proteolysis of NF-kappaB1 p105.

21 January 2018

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Toll-like receptor signalling

21 January 2018

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Inducible gene deletion reveals different roles for B-Raf and Raf-1 in B-cell antigen receptor signalling

21 January 2018

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Essential function for the kinase TAK1 in innate and adaptive immune responses.

21 January 2018

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Raf-induced proliferation or cell cycle arrest is determined by the level of Raf activity with arrest mediated by p21Cip1.

21 January 2018

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Role of TCR-induced extracellular signal-regulated kinase activation in the regulation of early IL-4 expression in naive CD4+ T cells

21 January 2018

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Direct phosphorylation of NF-kappaB1 p105 by the IkappaB kinase complex on serine 927 is essential for signal-induced p105 proteolysis

21 January 2018

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Plat-E: an efficient and stable system for transient packaging of retroviruses

21 January 2018

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Generation of large numbers of dendritic cells from mouse bone marrow cultures supplemented with granulocyte/macrophage colony-stimulating factor

21 January 2018

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betaTrCP-mediated proteolysis of NF-kappaB1 p105 requires phosphorylation of p105 serines 927 and 932.

21 January 2018

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The death domain of NF-kappa B1 p105 is essential for signal-induced p105 proteolysis

21 January 2018

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In vivo stimulation of I kappa B phosphorylation is not sufficient to activate NF-kappa B

21 January 2018

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Combined deficiency of p50 and cRel in CD4+ T cells reveals an essential requirement for nuclear factor kappaB in regulating mature T cell survival and in vivo function

21 January 2018

1 reference