Metabolic basis of visual cycle inhibition by retinoid and nonretinoid compounds in the vertebrate retina (Q28587431)

31 January 2017

title

Metabolic basis of visual cycle inhibition by retinoid and nonretinoid compounds in the vertebrate retina (English)

1 reference

Retinal pigment epithelium 65

31 January 2017

main subject

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GOA release 2020-03-11

9

Krzysztof Palczewski

1 reference

31 January 2017

7

Johannes von Lintig

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31 January 2017

1

Marcin Golczak

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31 January 2017

3

Grzegorz Bereta

1 reference

31 January 2017

2

Akiko Maeda

1 reference

31 January 2017

4

Tadao Maeda

1 reference

31 January 2017

5

Philip D. Kiser

1 reference

31 January 2017

8

William S. Blaner

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31 January 2017

6

Silke Hunzelmann

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31 January 2017

language of work or name

English

0 references

publication date

11 April 2008

1 reference

Journal of Biological Chemistry

31 January 2017

published in

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31 January 2017

volume

283

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31 January 2017

issue

15

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31 January 2017

page(s)

9543–9554

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Structural insights into the mechanism of amine oxidation by monoamine oxidases A and B

31 January 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2441898

A membrane receptor for retinol binding protein mediates cellular uptake of vitamin A

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2441898

RPE65 is the isomerohydrolase in the retinoid visual cycle

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2441898

Rpe65 is the retinoid isomerase in bovine retinal pigment epithelium

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2441898

Pathways of vitamin A delivery to the embryo: insights from a new tunable model of embryonic vitamin A deficiency

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2441898

Role of photoreceptor-specific retinol dehydrogenase in the retinoid cycle in vivo.

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2441898

Retinosomes: new insights into intracellular managing of hydrophobic substances in lipid bodies

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2441898

Noninvasive two-photon imaging reveals retinyl ester storage structures in the eye

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2441898

Retinol-binding protein-deficient mice: biochemical basis for impaired vision

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2441898

Recovery of visual functions in a mouse model of Leber congenital amaurosis

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2441898

Tobacco etch virus protease: mechanism of autolysis and rational design of stable mutants with wild-type catalytic proficiency

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2441898

Isomerization of 11-cis-retinoids to all-trans-retinoids in vitro and in vivo

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2441898

Mechanistic studies of rat protein farnesyltransferase indicate an associative transition state

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2441898

Impaired retinal function and vitamin A availability in mice lacking retinol-binding protein

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2441898

Metabolic inactivation of retinoic acid by a novel P450 differentially expressed in developing mouse embryos

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2441898

Reductions in Serum Vitamin A Arrest Accumulation of Toxic Retinal Fluorophores: A Potential Therapy for Treatment of Lipofuscin-Based Retinal Diseases

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2441898

Human cone photoreceptor dependence on RPE65 isomerase

23 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2441898

Sequestration of retinyl esters is essential for retinoid signaling in the zebrafish embryo

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2441898

Retinol dehydrogenase (RDH12) protects photoreceptors from light-induced degeneration in mice

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2441898

Diseases caused by defects in the visual cycle: retinoids as potential therapeutic agents

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2441898

Effects of potent inhibitors of the retinoid cycle on visual function and photoreceptor protection from light damage in mice

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2441898

G protein-coupled receptor rhodopsin

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2441898

Long-term restoration of rod and cone vision by single dose rAAV-mediated gene transfer to the retina in a canine model of childhood blindness

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2441898

Lecithin:retinol acyltransferase is responsible for amidation of retinylamine, a potent inhibitor of the retinoid cycle

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2441898

Mutation of key residues of RPE65 abolishes its enzymatic role as isomerohydrolase in the visual cycle.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2441898

Positively charged retinoids are potent and selective inhibitors of the trans-cis isomerization in the retinoid (visual) cycle

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2441898

The specific binding of retinoic acid to RPE65 and approaches to the treatment of macular degeneration

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2441898

Dark adaptation and the retinoid cycle of vision

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2441898

Light exposure stimulates formation of A2E oxiranes in a mouse model of Stargardt's macular degeneration

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2441898

Impairment of the transient pupillary light reflex in Rpe65(-/-) mice and humans with leber congenital amaurosis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2441898

Lecithin-retinol acyltransferase is essential for accumulation of all-trans-retinyl esters in the eye and in the liver.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2441898

Retinoid cycle in the vertebrate retina: experimental approaches and mechanisms of isomerization.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2441898

Retrovirus-mediated gene transfer and expression cloning: powerful tools in functional genomics

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2441898

Treatment with isotretinoin inhibits lipofuscin accumulation in a mouse model of recessive Stargardt's macular degeneration

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2441898

The lipofuscin component A2E selectively inhibits phagolysosomal degradation of photoreceptor phospholipid by the retinal pigment epithelium

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2441898

Identification of a novel phosphonocarboxylate inhibitor of Rab geranylgeranyl transferase that specifically prevents Rab prenylation in osteoclasts and macrophages.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2441898

Confronting complexity: the interlink of phototransduction and retinoid metabolism in the vertebrate retina

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2441898

Rapid restoration of visual pigment and function with oral retinoid in a mouse model of childhood blindness

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2441898

Biosynthesis of a major lipofuscin fluorophore in mice and humans with ABCR-mediated retinal and macular degeneration

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2441898

A mechanism for posttranslational modifications of proteins by yeast protein farnesyltransferase

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2441898

Interactions between the retinal pigment epithelium and the neural retina

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2441898

Small molecule RPE65 antagonists limit the visual cycle and prevent lipofuscin formation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2441898

Interaction of A2E with model membranes. Implications to the pathogenesis of age-related macular degeneration.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2441898

Multienzyme analysis of visual cycle

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2441898

Selective cytotoxicity of farnesylamine to pancreatic carcinoma cells and Ki-ras-transformed fibroblasts

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2441898

Farnesylamine: an inhibitor of farnesylation and growth of ras-transformed cells

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2441898

Retinoids, retinoid-binding proteins, and retinyl palmitate hydrolase distributions in different types of rat liver cells.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2441898

The molecular basis of retinoic acid induced night blindness

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2441898

Studies on geranylgeranyl diphosphate synthase from rat liver: specific inhibition by 3-azageranylgeranyl diphosphate

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2441898

Binding affinities of retinol and related compounds to retinol binding proteins

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2441898

Gene therapy restores vision in a canine model of childhood blindness

3 June 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708982200

Safety of recombinant adeno-associated virus type 2-RPE65 vector delivered by ocular subretinal injection

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708982200

Correlation of regenerable opsin with rod ERG signal in Rpe65-/- mice during development and aging

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708982200

Inhibition of the ATP-driven proton pump in RPE lysosomes by the major lipofuscin fluorophore A2-E may contribute to the pathogenesis of age-related macular degeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708982200

Farnesylamine from the ant Monomorium fieldi Forel

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708982200

Recombinant human retinol-binding protein refolding, native disulfide formation, and characterization

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708982200

Isolation and characterization of a monoamine oxidase inhibitor from tobacco leaves

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708982200

Fundus autofluorescence in children and teenagers with hereditary retinal diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708982200

Specificity of binding of all-trans-retinyl ester to RPE65.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708982200

Role of prenylation in the interaction of Rho-family small GTPases with GTPase activating proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708982200

Isotretinoin treatment inhibits lipofuscin accumulation in a mouse model of recessive Stargardt's macular degeneration

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2441898

The lipofuscin fluorophore A2E mediates blue light-induced damage to retinal pigmented epithelial cells.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2441898

Hyperlipofuscinosis and subretinal fibrosis in Stargardt's disease.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2441898

Thermodynamic parameters of the binding of retinol to binding proteins and to membranes

27 November 2018

1 reference

12 December 2020

Substrate specificities and mechanism in the enzymatic processing of vitamin A into 11-cis-retinol

1 reference

12 December 2020

Acyl-CoA:retinol acyltransferase and lecithin:retinol acyltransferase activities of bovine retinal pigment epithelial microsomes

1 reference

12 December 2020

In vitro interaction of fenretinide with plasma retinol-binding protein and its functional consequences

1 reference

12 December 2020

Ocular side effects of isotretinoin therapy

1 reference

12 December 2020

Age pigment structure

1 reference

12 December 2020

Rod outer segment retinol dehydrogenase: substrate specificity and role in phototransduction

1 reference

12 December 2020

Clinical pharmacology of all-trans retinoic acid

1 reference

12 December 2020

Effects of fenretinide (4-HPR) on dark adaptation

1 reference

12 December 2020

Preferential release of 11-cis-retinol from retinal pigment epithelial cells in the presence of cellular retinaldehyde-binding protein

1 reference

12 December 2020

Substrate specificities and 13-cis-retinoic acid inhibition of human, mouse and bovine cis-retinol dehydrogenases

1 reference

12 December 2020

Pilot trial of the safety, tolerability, and retinoid levels of N-(4-hydroxyphenyl) retinamide in combination with tamoxifen in patients at high risk for developing invasive breast cancer

1 reference

12 December 2020

Photodamage to human RPE cells by A2-E, a retinoid component of lipofuscin

1 reference

12 December 2020

Age-related Macular Degeneration

1 reference

12 December 2020

Identifiers

DOI

10.1074/JBC.M708982200

1 reference

31 January 2017

0 references

1 reference