Targeted deletion of titin N2B region leads to diastolic dysfunction and cardiac atrophy (Q28587704)

31 January 2017

title

Targeted deletion of titin N2B region leads to diastolic dysfunction and cardiac atrophy (English)

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31 January 2017

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GOA release 2020-03-11

Actinin alpha 2

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GOA release 2020-03-11

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Michael Gotthardt

7

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author name string

Michael H. Radke

1

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31 January 2017

Jun Peng

2

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31 January 2017

Yiming Wu

3

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31 January 2017

Mark McNabb

4

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31 January 2017

O. Lynne Nelson

5

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31 January 2017

Henk Granzier

6

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31 January 2017

language of work or name

English

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publication date

27 February 2007

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Proceedings of the National Academy of Sciences of the United States of America

31 January 2017

published in

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31 January 2017

volume

104

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31 January 2017

issue

9

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31 January 2017

page(s)

3444–3449

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M line-deficient titin causes cardiac lethality through impaired maturation of the sarcomere

31 January 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1805563

Subcellular targeting of metabolic enzymes to titin in heart muscle may be mediated by DRAL/FHL-2

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1805563

Titins: giant proteins in charge of muscle ultrastructure and elasticity

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1805563

High-efficiency deleter mice show that FLPe is an alternative to Cre-loxP

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1805563

The giant protein titin: a major player in myocardial mechanics, signaling, and disease

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1805563

Cardiac titin: an adjustable multi-functional spring

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1805563

Extensibility of isoforms of cardiac titin: variation in contour length of molecular subsegments provides a basis for cellular passive stiffness diversity

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1805563

Molecular dissection of N2B cardiac titin's extensibility

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1805563

I-band titin in cardiac muscle is a three-element molecular spring and is critical for maintaining thin filament structure

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1805563

The giant protein titin. Emerging roles in physiology and pathophysiology

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1805563

Passive tension in cardiac muscle: contribution of collagen, titin, microtubules, and intermediate filaments

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1805563

Cardiac-specific LIM protein FHL2 modifies the hypertrophic response to beta-adrenergic stimulation

29 September 2017

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0608543104

Mechanism of altered patterns of left ventricular filling during the development of congestive heart failure.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0608543104

Conditional expression of mutant M-line titins results in cardiomyopathy with altered sarcomere structure

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0608543104

Association of the chaperone alphaB-crystallin with titin in heart muscle.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0608543104

Vertical agarose gel electrophoresis and electroblotting of high-molecular-weight proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0608543104

Cardiomyopathy in zebrafish due to mutation in an alternatively spliced exon of titin

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1805563

Estimation of left ventricular operating stiffness from Doppler early filling deceleration time in humans.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1805563

Changes in titin and collagen underlie diastolic stiffness diversity of cardiac muscle

27 November 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/17360664

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Mechanically driven contour-length adjustment in rat cardiac titin's unique N2B sequence: titin is an adjustable spring.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17360664

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Functional analysis of titin/connectin N2-B mutations found in cardiomyopathy

1 reference

https://pubmed.ncbi.nlm.nih.gov/17360664

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.0608543104

1 reference

ADS bibcode

2007PNAS..104.3444R

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