Ctr2 regulates biogenesis of a cleaved form of mammalian Ctr1 metal transporter lacking the copper- and cisplatin-binding ecto-domain (Q28589065)

Solute carrier family 31, member 2

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

copper

0 references

author name string

Helena Öhrvik

1

1 reference

31 January 2017

Yasuhiro Nose

2

1 reference

31 January 2017

L. Kent Wood

3

1 reference

31 January 2017

Byung-Eun Kim

4

1 reference

31 January 2017

Sophie-Charlotte Gleber

5

1 reference

31 January 2017

Martina Ralle

6

1 reference

31 January 2017

Dennis J. Thiele

Proceedings of the National Academy of Sciences of the United States of America

7

1 reference

31 January 2017

language of work or name

English

0 references

publication date

12 November 2013

1 reference

31 January 2017

1 reference

31 January 2017

110

1 reference

31 January 2017

E4279–4288

1 reference

31 January 2017

46

1 reference

31 January 2017

1 reference

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Human copper transporter 2 is localized in late endosomes and lysosomes and facilitates cellular copper uptake

17 March 2017

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Cisplatin stabilizes a multimeric complex of the human Ctr1 copper transporter: requirement for the extracellular methionine-rich clusters

17 March 2017

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Copper-stimulated endocytosis and degradation of the human copper transporter, hCtr1

17 March 2017

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Characterization of mouse embryonic cells deficient in the ctr1 high affinity copper transporter. Identification of a Ctr1-independent copper transport system

17 March 2017

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Biochemical characterization and subcellular localization of human copper transporter 1 (hCTR1)

17 March 2017

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Biochemical and genetic analyses of yeast and human high affinity copper transporters suggest a conserved mechanism for copper uptake

17 March 2017

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The copper transporter CTR1 provides an essential function in mammalian embryonic development

17 March 2017

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Characterization of the Saccharomyces cerevisiae high affinity copper transporter Ctr3.

17 March 2017

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The Saccharomyces cerevisiae copper transport protein (Ctr1p). Biochemical characterization, regulation by copper, and physiologic role in copper uptake.

17 March 2017

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17 March 2017

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Opportunities in multidimensional trace metal imaging: taking copper-associated disease research to the next level

17 March 2017

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Iron transport machinery of human cells: players and their interactions

29 September 2017

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Role of the human high-affinity copper transporter in copper homeostasis regulation and cisplatin sensitivity in cancer chemotherapy

29 September 2017

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29 September 2017

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Predictive and prognostic value of human copper transporter 1 (hCtr1) in patients with stage III non-small-cell lung cancer receiving first-line platinum-based doublet chemotherapy

29 September 2017

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Calcium-dependent copper redistributions in neuronal cells revealed by a fluorescent copper sensor and X-ray fluorescence microscopy.

29 September 2017

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Model peptides provide new insights into the role of histidine residues as potential ligands in human cellular copper acquisition via Ctr1.

29 September 2017

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Copper transporter 2 regulates endocytosis and controls tumor growth and sensitivity to cisplatin in vivo

29 September 2017

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Ctr1 is an apical copper transporter in mammalian intestinal epithelial cells in vivo that is controlled at the level of protein stability

29 September 2017

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The role of the methionines and histidines in the transmembrane domain of mammalian copper transporter 1 in the cellular accumulation of cisplatin

29 September 2017

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The role of the N-terminus of mammalian copper transporter 1 in the cellular accumulation of cisplatin

29 September 2017

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Cardiac copper deficiency activates a systemic signaling mechanism that communicates with the copper acquisition and storage organs

29 September 2017

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Metabolic crossroads of iron and copper

29 September 2017

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Copper transporters and the cellular pharmacology of the platinum-containing cancer drugs

29 September 2017

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Copper-dependent recycling of hCTR1, the human high affinity copper transporter.

29 September 2017

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Human copper transporter 1 lacking O-linked glycosylation is proteolytically cleaved in a Rab9-positive endosomal compartment.

29 September 2017

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Copper transporter 2 regulates the cellular accumulation and cytotoxicity of Cisplatin and Carboplatin

29 September 2017

1 reference

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Three-dimensional structure of the human copper transporter hCTR1.

29 September 2017

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Quantitative imaging of metals in tissues

29 September 2017

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Deletion of hepatic Ctr1 reveals its function in copper acquisition and compensatory mechanisms for copper homeostasis

29 September 2017

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Variable response of selected cuproproteins in rat choroid plexus and cerebellum following perinatal copper deficiency

29 September 2017

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Metals in Alzheimer's and Parkinson's diseases

29 September 2017

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Mechanisms for copper acquisition, distribution and regulation

29 September 2017

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Function and regulation of human copper-transporting ATPases

29 September 2017

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29 September 2017

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29 September 2017

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The internalization and degradation of human copper transporter 1 following cisplatin exposure

29 September 2017

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Mechanisms of the copper-dependent turnover of the copper chaperone for superoxide dismutase

29 September 2017

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A selective turn-on fluorescent sensor for imaging copper in living cells.

29 September 2017

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Copper transport protein (Ctr1) levels in mice are tissue specific and dependent on copper status

29 September 2017

1 reference

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Uptake of the anticancer drug cisplatin mediated by the copper transporter Ctr1 in yeast and mammals

29 September 2017

1 reference

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High affinity copper transport protein in the lizard Podarcis sicula: molecular cloning, functional characterization and expression in somatic tissues, follicular oocytes and eggs.

29 September 2017

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Essential role for mammalian copper transporter Ctr1 in copper homeostasis and embryonic development

29 September 2017

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A unified perspective on copper deficiency and cardiomyopathy

29 September 2017

1 reference

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Effects of copper deficiency on the immune system.

29 September 2017

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Kinetics and thermodynamics of metal binding to the N-terminus of a human copper transporter, hCTR1.

29 September 2017

1 reference

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Coordination of platinum therapeutic agents to met-rich motifs of human copper transport protein1.

27 November 2018

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Ctr2 is partially localized to the plasma membrane and stimulates copper uptake in COS-7 cells.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3831961

Distinct mechanisms for Ctr1-mediated copper and cisplatin transport.

27 November 2018

1 reference

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Drosophila Ctr1A functions as a copper transporter essential for development.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3831961

O-linked glycosylation at threonine 27 protects the copper transporter hCTR1 from proteolytic cleavage in mammalian cells.

27 November 2018

1 reference

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A Mets motif peptide found in copper transport proteins selectively binds Cu(I) with methionine-only coordination.

27 November 2018

1 reference

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Identification of a copper transporter family in Arabidopsis thaliana.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3831961

Isolation of a murine copper transporter gene, tissue specific expression and functional complementation of a yeast copper transport mutant.

27 November 2018

1 reference

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Structure and function of copper uptake transporters

27 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24167251

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Ctr1 drives intestinal copper absorption and is essential for growth, iron metabolism, and neonatal cardiac function

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24167251

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.1311749110

1 reference

31 January 2017

0 references

release_lytnuv3r5vbm5bbnlnajymg2v4

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/lytnuv3r5vbm5bbnlnajymg2v4