Editing-defective tRNA synthetase causes protein misfolding and neurodegeneration (Q28590188)

31 January 2017

title

Editing-defective tRNA synthetase causes protein misfolding and neurodegeneration (English)

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31 January 2017

main subject

Alanyl-tRNA synthetase

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Heat shock protein 1A

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Heat shock protein 8

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Heat shock protein 5

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7

Muriel T. Davisson

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31 January 2017

9

Paul Schimmel

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31 January 2017

Jeong Woong Lee

1

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31 January 2017

Kirk Beebe

2

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31 January 2017

Leslie A. Nangle

3

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31 January 2017

Jaeseon Jang

4

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31 January 2017

Chantal M. Longo-Guess

5

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31 January 2017

Susan A. Cook

6

1 reference

31 January 2017

John P. Sundberg

8

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31 January 2017

Susan L. Ackerman

10

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31 January 2017

language of work or name

English

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publication date

7 September 2006

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31 January 2017

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31 January 2017

volume

443

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31 January 2017

issue

7107

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31 January 2017

page(s)

50–55

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Folding proteins in fatal ways

31 January 2017

cites work

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Protein folding and misfolding

21 April 2017

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Protein aggregation and neurodegenerative disease

21 April 2017

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Wide cross-species aminoacyl-tRNA synthetase replacement in vivo: yeast cytoplasmic alanine enzyme replaced by human polymyositis serum antigen

21 April 2017

1 reference

Endoplasmic reticulum stress: cell life and death decisions.

21 April 2017

1 reference

Trans-editing of mischarged tRNAs

21 April 2017

1 reference

The gene disrupted in Marinesco-Sjögren syndrome encodes SIL1, an HSPA5 cochaperone

21 April 2017

1 reference

Protein accumulation and neurodegeneration in the woozy mutant mouse is caused by disruption of SIL1, a cochaperone of BiP

21 April 2017

1 reference

The mouse rostral cerebellar malformation gene encodes an UNC-5-like protein

21 April 2017

1 reference

The frequency of errors in protein biosynthesis

21 April 2017

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05096

7 January 2021

Inhibited cell growth and protein functional changes from an editing-defective tRNA synthetase

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05096

7 January 2021

Enlarging the amino acid set of Escherichia coli by infiltration of the valine coding pathway

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05096

7 January 2021

Genetic code ambiguity. Cell viability related to the severity of editing defects in mutant tRNA synthetases

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05096

7 January 2021

Artificially ambiguous genetic code confers growth yield advantage

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05096

7 January 2021

Transfer RNA-mediated editing in threonyl-tRNA synthetase. The class II solution to the double discrimination problem

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05096

7 January 2021

Elucidation of tRNA-dependent editing by a class II tRNA synthetase and significance for cell viability

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05096

7 January 2021

Evidence that a major determinant for the identity of a transfer RNA is conserved in evolution

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05096

7 January 2021

A simple structural feature is a major determinant of the identity of a transfer RNA

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05096

7 January 2021

The ubiquitin-proteasome pathway in Parkinson's disease and other neurodegenerative diseases

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05096

7 January 2021

Role of quality control pathways in human diseases involving protein misfolding

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05096

7 January 2021

Principles of protein folding, misfolding and aggregation

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05096

7 January 2021

Roles of molecular chaperones in protein misfolding diseases

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05096

7 January 2021

Modulation of neurodegeneration by molecular chaperones

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05096

7 January 2021

CHOP is implicated in programmed cell death in response to impaired function of the endoplasmic reticulum

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05096

7 January 2021

Peptide aggregation in neurodegenerative disease

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05096

7 January 2021

Molecular basis of alanine discrimination in editing site

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05096

7 January 2021

Diseases of unstable repeat expansion: mechanisms and common principles

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05096

7 January 2021

Mutations in SIL1 cause Marinesco-Sjögren syndrome, a cerebellar ataxia with cataract and myopathy

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05096

7 January 2021

Purification of hyperexpressed Bacillus subtilis tRNATrp cloned in Escherichia coli

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05096

7 January 2021

A domain for editing by an archaebacterial tRNA synthetase

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05096

7 January 2021

Identification of thermodynamically relevant interactions between EF-Tu and backbone elements of tRNA.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05096

7 January 2021

Alanyl-tRNA synthetase crystal structure and design for acceptor-stem recognition

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05096

7 January 2021

Global effects of mistranslation from an editing defect in mammalian cells

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05096

7 January 2021