Non-redundant role of Shc in Erk activation by cytoskeletal reorganization (Q28590354)

31 January 2017

title

Non-redundant role of Shc in Erk activation by cytoskeletal reorganization (English)

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STT3, subunit of the oligosaccharyltransferase complex, homolog A (S. cerevisiae)

31 January 2017

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1 reference

GOA release 2020-03-11

author name string

Amir Faisal

series ordinal

1

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31 January 2017

Sandra Kleiner

series ordinal

2

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31 January 2017

Yoshikuni Nagamine

series ordinal

3

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31 January 2017

language of work or name

English

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publication date

30 January 2004

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Journal of Biological Chemistry

31 January 2017

published in

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31 January 2017

volume

279

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31 January 2017

issue

5

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31 January 2017

page(s)

3202–3211

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Not all Shc's roads lead to Ras

31 January 2017

cites work

1 reference

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Signaling via Shc family adapter proteins

21 January 2018

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Association of the Shc and Grb2/Sem5 SH2-containing proteins is implicated in activation of the Ras pathway by tyrosine kinases

21 January 2018

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21 January 2018

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21 January 2018

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The Shc adaptor protein is highly phosphorylated at conserved, twin tyrosine residues (Y239/240) that mediate protein-protein interactions

21 January 2018

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Serine/threonine phosphorylation of ShcA. Regulation of protein-tyrosine phosphatase-pest binding and involvement in insulin signaling.

21 January 2018

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Opposite effects of the p52shc/p46shc and p66shc splicing isoforms on the EGF receptor-MAP kinase-fos signalling pathway.

21 January 2018

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The p66shc adaptor protein controls oxidative stress response and life span in mammals

21 January 2018

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Hierarchy of binding sites for Grb2 and Shc on the epidermal growth factor receptor

21 January 2018

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Tyr-716 in the platelet-derived growth factor beta-receptor kinase insert is involved in GRB2 binding and Ras activation

21 January 2018

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Multiple Grb2-mediated integrin-stimulated signaling pathways to ERK2/mitogen-activated protein kinase: summation of both c-Src- and focal adhesion kinase-initiated tyrosine phosphorylation events

21 January 2018

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Multiple ErbB-2/Neu Phosphorylation Sites Mediate Transformation through Distinct Effector Proteins.

21 January 2018

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Use of signal specific receptor tyrosine kinase oncoproteins reveals that pathways downstream from Grb2 or Shc are sufficient for cell transformation and metastasis

21 January 2018

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Bridging cytoskeletal intersections.

21 January 2018

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Changes in cell shape correlate with collagenase gene expression in rabbit synovial fibroblasts

21 January 2018

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Disruption of the cytoskeleton with cytochalasin D induces c-fos gene expression.

21 January 2018

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Cytoskeleton reorganization induces the urokinase-type plasminogen activator gene via the Ras/extracellular signal-regulated kinase (ERK) signaling pathway

21 January 2018

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Cytoskeleton regulates expression of genes for transforming growth factor-beta 1 and extracellular matrix proteins in dermal fibroblasts.

21 January 2018

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Microtubule-interfering Agents Activate c-Jun N-terminal Kinase/Stress-activated Protein Kinase through Both Ras and Apoptosis Signal-regulating Kinase Pathways

21 January 2018

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Cytoskeletal reorganization leads to induction of the urokinase-type plasminogen activator gene by activating FAK and Src and subsequently the Ras/Erk signaling pathway

21 January 2018

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MEK kinase 1 (MEKK1) transduces c-Jun NH2-terminal kinase activation in response to changes in the microtubule cytoskeleton.

21 January 2018

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Microtubule integrity regulates src-like and extracellular signal-regulated kinase activities in human pro-monocytic cells. Importance for interleukin-1 production

21 January 2018

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Microtubule-interfering agents stimulate the transcription of cyclooxygenase-2. Evidence for involvement of ERK1/2 AND p38 mitogen-activated protein kinase pathways

21 January 2018

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21 January 2018

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Integrin-mediated signal transduction linked to Ras pathway by GRB2 binding to focal adhesion kinase

21 January 2018

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Isoform-specific knockdown and expression of adaptor protein ShcA using small interfering RNA.

21 January 2018

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A new genetic approach for studying hormonal regulation of urokinase-type plasminogen activator gene expression in LLC-PK1 cells

21 January 2018

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Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells

21 January 2018

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Single-chain antibody-mediated intracellular retention of ErbB-2 impairs Neu differentiation factor and epidermal growth factor signaling

21 January 2018

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Relative involvement of Shc tyrosine 239/240 and tyrosine 317 on insulin induced mitogenic signaling in rat1 fibroblasts expressing insulin receptors.

21 January 2018

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N-Shc and Sck, two neuronally expressed Shc adapter homologs. Their differential regional expression in the brain and roles in neurotrophin and Src signaling

21 January 2018

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Discrimination between phosphotyrosine-mediated signaling properties of conventional and neuronal Shc adapter molecules.

21 January 2018

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Genomic organization of the Shc-related phosphotyrosine adapters and characterization of the full-length Sck/ShcB: specific association of p68-Sck/ShcB with pp135

21 January 2018

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The 66-kDa Shc isoform is a negative regulator of the epidermal growth factor-stimulated mitogen-activated protein kinase pathway

21 January 2018

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pp60c‐src mediates ERK activation/nuclear localization and PAI‐1 gene expression in response to cellular deformation

21 January 2018

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EGF receptor-mediated, c-Src-dependent, activation of Stat5b is downregulated in mitogenically responsive hepatocytes

21 January 2018

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Specificity and mechanism of action of some commonly used protein kinase inhibitors

21 January 2018

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Regulation of the small GTP-binding protein Rho by cell adhesion and the cytoskeleton

21 January 2018

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A new method for isolating tyrosine kinase substrates used to identify fish, an SH3 and PX domain-containing protein, and Src substrate

21 January 2018

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Distinct pathways in the over-expression of matrix metalloproteinases in human fibroblasts by relaxation of mechanical tension

21 January 2018

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Roles of Lck, Syk and ZAP-70 tyrosine kinases in TCR-mediated phosphorylation of the adapter protein Shc

21 January 2018

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SU6656, a selective src family kinase inhibitor, used to probe growth factor signaling

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M310010200

1 reference

31 January 2017

1 reference