The RNAseIII enzyme Drosha is critical in T cells for preventing lethal inflammatory disease (Q28591855)

GOA release 2020-03-11

Endoribonuclease Dicer

1 reference

Journal of Experimental Medicine

GOA release 2020-03-11

5

Dan R. Littman

1 reference

31 January 2017

Mark M. W. Chong

1

1 reference

31 January 2017

Jeffrey P. Rasmussen

series ordinal

2

1 reference

31 January 2017

Alexander Y. Rudensky

series ordinal

3

1 reference

31 January 2017

Alexander Y. Rundensky

series ordinal

4

1 reference

31 January 2017

language of work or name

English

0 references

publication date

1 September 2008

1 reference

31 January 2017

1 reference

31 January 2017

205

1 reference

31 January 2017

2005–2017

1 reference

31 January 2017

9

1 reference

31 January 2017

Pseudogene-derived small interfering RNAs regulate gene expression in mouse oocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2526196

Endogenous siRNAs from naturally formed dsRNAs regulate transcripts in mouse oocytes

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2526196

The biological functions of T helper 17 cell effector cytokines in inflammation

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2526196

Lymphoproliferative disease and autoimmunity in mice with increased miR-17-92 expression in lymphocytes

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2526196

MicroRNA expression is required for pancreatic islet cell genesis in the mouse

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2526196

Cerebellar neurodegeneration in the absence of microRNAs

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2526196

miR-181a is an intrinsic modulator of T cell sensitivity and selection

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2526196

RNASEN regulates cell proliferation and affects survival in esophageal cancer patients

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2526196

The orphan nuclear receptor RORgammat directs the differentiation program of proinflammatory IL-17+ T helper cells

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2526196

Molecular basis for the recognition of primary microRNAs by the Drosha-DGCR8 complex

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2526196

Oncomirs - microRNAs with a role in cancer

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2526196

The RNaseIII enzyme Dicer is required for morphogenesis but not patterning of the vertebrate limb

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2526196

TRBP recruits the Dicer complex to Ago2 for microRNA processing and gene silencing

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2526196

Regulatory T cell lineage specification by the forkhead transcription factor foxp3

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2526196

Conversion of peripheral CD4+CD25- naive T cells to CD4+CD25+ regulatory T cells by TGF-beta induction of transcription factor Foxp3

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2526196

Dicer is essential for mouse development

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2526196

The nuclear RNase III Drosha initiates microRNA processing

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2526196

Control of regulatory T cell development by the transcription factor Foxp3

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2526196

An abundant class of tiny RNAs with probable regulatory roles in Caenorhabditis elegans

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2526196

Disruption of a new forkhead/winged-helix protein, scurfin, results in the fatal lymphoproliferative disorder of the scurfy mouse

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2526196

Human RNase III is a 160-kDa protein involved in preribosomal RNA processing

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2526196

Reciprocal TH17 and regulatory T cell differentiation mediated by retinoic acid

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2526196

A role for the RNase III enzyme DCR-1 in RNA interference and germ line development in Caenorhabditis elegans

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2526196

X-linked neonatal diabetes mellitus, enteropathy and endocrinopathy syndrome is the human equivalent of mouse scurfy

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2526196

Illuminating the silence: understanding the structure and function of small RNAs

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2526196

Regulatory T cells prevent catastrophic autoimmunity throughout the lifespan of mice

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2526196

Regulatory T cell-derived interleukin-10 limits inflammation at environmental interfaces

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2526196

Dicer loss in striatal neurons produces behavioral and neuroanatomical phenotypes in the absence of neurodegeneration

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2526196

Apoptosis regulators Fas and Bim cooperate in shutdown of chronic immune responses and prevention of autoimmunity

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2526196

Essential role for Dicer during skeletal muscle development.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2526196

All-trans retinoic acid mediates enhanced T reg cell growth, differentiation, and gut homing in the face of high levels of co-stimulation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2526196

Oncogenic All1 fusion proteins target Drosha-mediated microRNA processing

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2526196

Natural regulatory T cells: mechanisms of suppression

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2526196

A role for Dicer in immune regulation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2526196

Signals transducers and activators of transcription (STAT)-induced STAT inhibitor-1 (SSI-1)/suppressor of cytokine signaling-1 (SOCS-1) suppresses tumor necrosis factor alpha-induced cell death in fibroblasts

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2526196

Dicer ablation affects antibody diversity and cell survival in the B lymphocyte lineage

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2526196

Nonself-antigens are the cognate specificities of Foxp3+ regulatory T cells

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2526196

Apoptosis regulators Bim and Fas function concurrently to control autoimmunity and CD8+ T cell contraction

3 June 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20081219

SOCS1 is a critical inhibitor of interferon gamma signaling and prevents the potentially fatal neonatal actions of this cytokine.

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20081219

Suppressor of Cytokine Signaling-1 Has IFN- -Independent Actions in T Cell Homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20081219

Inactivation of Notch 1 in immature thymocytes does not perturb CD4 or CD8T cell development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20081219

Global microRNA profiles in cervical squamous cell carcinoma depend on Drosha expression levels.

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20081219

A rare polyadenylation signal mutation of the FOXP3 gene (AAUAAA-->AAUGAA) leads to the IPEX syndrome

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18725527

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Recognition of the peripheral self by naturally arising CD25+ CD4+ T cell receptors

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18725527

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Combined deficiency of proapoptotic regulators Bim and Fas results in the early onset of systemic autoimmunity

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18725527

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1084/JEM.20081219

1 reference

1233543

1233543

1 reference

1 reference

1 reference